Hélène Eltchaninoff CHU Rouen, France

Symposium Edwards Valves Aortiques

Hightech 2012 - MARSEILLE

Le futur

•Nouvelle technologie

• Etudes

20mm*

SAPIEN XT, disponible en 4 tailles

SAPIEN XT THV*

Hors USAHors USA

Voies Transapicale et TransaortiqueVoies Transapicale et Transaortique

Voie TransfémoraleVoie Transfémorale

NovaFlex+with eSheath

Ascendra+*

Annulus Size (mm)

23mm26mm

29mm*Tailles

12/9/2011

Japan EU

……Expect CE Mark Trials on Two New Valve Expect CE Mark Trials on Two New Valve Platforms in 2012Platforms in 2012

12/9/2011

Balloon-Expandable

SAPIEN XT THV

O.U.S. Commercial Offering

……Expect CE Mark Trials on Two New Valve Expect CE Mark Trials on Two New Valve Platforms in 2012Platforms in 2012

12/9/2011

Balloon Expandable Self-ExpandingBalloon-Expandable

SAPIEN XT THV

O.U.S. Commercial Offering

Edwards SAPIEN 3 ValveEdwards SAPIEN 3 ValveUltra Low-Profile Balloon Expandable Platform

SAPIEN 3 Valve

•Designed to further reduce PV leaks

•Lower profile valve : 14 Fr eSheath

•Discrete valve that anchors in the annulus

•Treated bovine pericardial tissue leaflets

•Dramatically reduced profile for the transapical approach

12/9/2011

Edwards CENTERA ValveEdwards CENTERA Valve

CENTERA is Edwards’ First Self- Expanding Transcatheter Valve

•Motorized delivery system for stable deployment and single operator use

•Repositionable

•Delivered through a 14 Fr eSheath

•Discrete valve that anchors in the annulus

•Treated bovine pericardial tissue leaflets

•Transfemoral and subclavian approach

12/9/2011

Ultra Low-Profile Self Expanding Platform

First-in-Man Experience CompletedFirst-in-Man Experience Completed

Les études en cours et à venir

• PARTNER 2: Critère combiné décès + AVC

1) SAPIEN XT vs RVA

STS < 4%

2) SAPIEN vs SAPIEN XT

Pts inopérables

USA

• PROTAVI-C: AVC et IRM (Embrella)