exon 4 exon 5
1
exon 4 exon 5 Frt LoxP LoxP Mouse with Floxed Mouse with Floxed BMPRII BMPRII SM 22 TRE-P TRE-P min min CMV CMV CRE tTA Doxycyclin Doxycyclin e e CRE TRE-P TRE-P min min CMV CMV Target Target Transactiva Transactiva tor tor tTA SM 22 SM22 SM22 -tTA -tTA + /Cre /Cre + TRE-P TRE-P min min CMV CMV CRE tTA SM 22 X Frt LoxP Mouse with Mouse with conditionally conditionally deleted BMPRII in deleted BMPRII in SMC SMC X
description
Target. Transactivator. X. Mouse with Floxed BMPRII. TRE-P min CMV. CRE. SM 22 a. tTA. SM22 -tTA + /Cre +. CRE. CRE. TRE-P min CMV. TRE-P min CMV. tTA. SM 22 a. exon 4 exon 5. Frt LoxP LoxP. SM 22 a. tTA. Doxycycline. Frt LoxP. - PowerPoint PPT Presentation
Transcript of exon 4 exon 5
exon 4 exon 5
Frt LoxP LoxP
Mouse with Floxed Mouse with Floxed BMPRIIBMPRII
SM 22
TRE-PTRE-PminminCMVCMV CRE
tTA
DoxycyclineDoxycycline
CRETRE-PTRE-PminminCMVCMV
TargetTargetTransactivatorTransactivator
tTASM 22
SM22SM22-tTA-tTA++/Cre/Cre++
TRE-PTRE-PminminCMVCMV CRE
tTASM 22
X
Frt LoxP
Mouse with Mouse with conditionally deleted conditionally deleted
BMPRII in SMCBMPRII in SMC
X