科目名 Course Title 化学研究先端講義 [Topical Lectures in … · 2018-06-12 · This...

科目名 Course Title 化学研究先端講義 [Topical Lectures in Chemical Sciences and Engineering]

講義題目 Subtitle

責任教員 Instructor 村上洋太 [Yota MURAKAMI] (Faculty of Science)

担当教員 Other Instructors

開講年度 Year 2018 時間割番号Course Number 094401

期間 Semester Irregular 単位数 Number of Credits 1

授業形態 Type of Class Lecture 対象年次 Year of Eligible Students ～

ナンバリングコード Numbering Code CHEM_ELCOM 6001

キーワード Key Words

Cutting Edge Researches in Chemistry, Foreign Lecturers, English Lectures

授業の目標 Course Objectives

A series of English lectures on cutting edge researches in chemistry will provide enough knowledge and information on understanding recent

progress in chemistry.

到達目標 Course Goals

Students will learn the background and recent progress in cutting edge researches in chemistry. Communicating with English speaking

lecturers will be expected.

授業計画 Course Schedule

Invited English speaking lecturers will give lectures on their recent researches in various fields of chemistry and discuss their topics with

students.

準備学習（予習・復習）等の内容と分量 Homework

Assignments will be required by lecturers.

成績評価の基準と方法 Grading System

Class participation (more than 7 lectures) and report.

テキスト・教科書 Textbooks

講義指定図書 Reading List

参照ホームページ Websites

研究室のホームページ Website of Laboratory

備考 Additional Information

科目名 Course Title 総合化学研究先端講義 [Internship]


責任教員 Instructor 仙北久典 [Hisanori SENBOKU] (Faculty of Engineering)



期間 Semester Fall 単位数 Number of Credits 1

授業形態 Type of Class Internship 対象年次 Year of Eligible Students ～



Internship（domestic and oversea）


Students improve their skill and knowledge by being engaged in an actual work relating their future career.

For overseas internship, students develop global vision by their experience overseas, gain expertise and experimental techniques which seem

to be hard to obtain in Japan.


Students start to contact with where to do internship, then improve skills of communication, language, research practice, research network and

community formation etc, so that they can raise consciousness as an engineer or a researcher.

For overseas internship, students should try not to keep the experience at only level of basic studies, try to apply the experience to collaborative

researches with a practical level in the future.


The program will be generally conducted following the schedule below.

１．Announcement

２．Application (not equal to Registration)

３．Preparation

４．Internship for about between two weeks and two months

５．Submission of a report for the internship, presentation


Students need to do preliminary search and to prepare ecperiments in advance.


Basically, students must submit a report and do a presentation (in English language for overseas internship).

They will be evaluated by the above elements.


使用しない


使用しない




科目名 Course Title 化学産業実学 [Industrial Practice in Chemical Processes]


責任教員 Instructor 西田まゆみ [Mayumi NISHIDA] (Institute for Catalysis)













教科書はとくに指定せず、Lecture 時はパワーポイントを使用する。





科目名 Course Title 先端計測化学 [Advanced Instrumental Analysis]


責任教員 Instructor 村越敬 [Kei MURAKOSHI] (Faculty of Science)

担当教員 Other Instructors Noboru KITAMURA(Faculty of Science), Manabu TOKESHI(Faculty of Engineering),

Hirofumi TANI(Faculty of Engineering)






Molecular Spectroscopy, Microspectroscopy, Microscopy, Thermal/Mass Analysis


This course investigates basic concepts and characteristics of modern instrumental analysis methods for molecular and materials systems.


The students will be able to learn basic concepts and characteristics of

- modern spectroscopy including microspectroscopy and molecular imaging

- scanning probe microscopy

- single atom/molecule spectroscopy

- thermal and mass spectroscopy


K. Murakoshi lectures)

- Raman Microspectroscopy / Surface Enhanced Raman Spectroscopy / Single Atom/Molecule Spectroscopy

N. Kitamura (3 lectures)

- Molecular excited-state chemistry / Molecular Spectroscopy (Reflection Spectroscopy) / Microspectroscopy / Microscopy

M. Tokoshi (1 lecture)

- Thermal and Mass Analysis

H. Tani (1 lecture)

- Chemiluminescence


Basic analytical and physical chemistry in undergraduate level


Assignment on a specified subject regarding to "Advanced Instrumental Analysis" (60%).

In addition, we also consider it as the important factor for assessment how actively students participate in each class (40%).


なし。必要に応じて資料プリントを配布する。

Handouts will be provided.





科目名 Course Title マイクロ・ナノ化学 [Micro-Nanochemistry]


責任教員 Instructor 渡慶次学 [Manabu TOKESHI] (Faculty of Engineering)

担当教員 Other Instructors Noboru KITAMURA(Faculty of Science), Kei MURAKOSHI(Faculty of Science),

Hirofumi TANI(Faculty of Engineering), Shinichiro FUJITA(Faculty of Engineering)






Microchemistry, Nanochemistry, Microchip, Biochip, Microreactor, Single Atom/Molecule Manipulation


This course investigates modern chemistry in micrometer - nanometer dimensions including microfabrication technologies in chemistry,

microchips/biochips, and microreactors.


The students will be able to learn the basic concents and characteristics of

-Fundamental aspects in microfabrication techniques

-Chemical applications of microchips/biochips and microreactors

-Single molecular and atom manipulation techniques


M. Tokeshi (2 lectures)

- Historical background of micro-nanochemistry /State of the art technologies and recent topics in Microchips/Biochips

N. Kitamura (2 lectures)

- Microfabrication techniaues / Microchips / Miroreactors

K. Murakoshi (2 lectures)

- Single atom/molecule manipulation / Nanochemistry

H. Tani (1 lecture)

- Biochip

S. Fujita (1 lecture)

- Microreactors


Basic analytical and physical chemistry in undergraduate level


Learning attitude and report


なし。適宜，資料を配布する





科目名 Course Title 生命分子化学特論 [Modern Trends in Biomolecular Chemistry]


責任教員 Instructor 髙木睦 [Mutsumi TAKAGI] (Faculty of Engineering)

担当教員 Other Instructors Hideaki OIKAWA(Faculty of Science), Kazuyasu SAKAGUCHI(Faculty of Science), Yota

MURAKAMI(Faculty of Science), Takeshi UCHIDA(Faculty of Science), Toshihiko OI(Faculty of

Engineering), Kenji TAJIMA(Faculty of Engineering), Kenichiro MATSUMOTO(Faculty of Engineering)


期間 Semester Summer 単位数 Number of Credits 1




Genetic information, protein structure, molecular mechanism, biosynthetic mechanism, animal cells, secondary metabolites, biopolymers,

bioremediation


Synthesis, structure, function, and novel engineering subjects on of bio-molecules will be studied focusing on the fields of life science,

information, medicine, and environment.


Students are expected to understand deeply the topics of genetic information, protein structure, animal cell cultivation, secondary metabolites,

biopolymers, and clean environments in the fields of life science, information, medicine, and environment.


１．Advanced concepts and cutting edge techniques to understand molecular functions and structures of biomolecules essential for life will be

introduced based on the basic theories and the applications. Recent progresses and future developments in molecular understanding of life

will also be discussed.

２．This lecture outlines methodologies to analyze structures and functions of protein that is a main molecule in biological activity of life, and

illustrates by examples in biochemical study.

３．Cells produce various proteins based on the genetic information for their maintenance and inheritance. Recent study revealed that small

RNA plays an important role in the cell. The production and the function of the small RNA will be introduced. The application of the small RNA

in medicine, such as cancer treatment, will be also discussed.

４．Cell adhesion process essential for animal cell and related signal transduction will be introduced.

５．Nature creates a number of structurally diverse and biologically active secondary metabolites. Based on knowledge of organic chemistry,

representative biosynthetic strategy will be introduced using uncovered data and be discussed on the view of problems concerning application

of organic synthesis.

６．Cells produce various kinds of polysaccharides, that play a critical role. Many proteins are associated with polysaccharide synthesis, and

biosynthetic mechanism including protein structures will be introduced.

７．All processes of synthesis, regulation and degradation of biopolymers are discussed in terms that how biotechnology contributes to the

global environments issues of 21th century.

８．The treatment of environmental problems through biological process means is known as bioremediation. The perspective of the application

based on the biological reactions will be overviewed.


Students are asked to submit a report on the subject which instructor give every time.


Attendance ( > 70%) and reports.


適宜資料を配布する。





科目名 Course Title 総合化学特論Ⅰ(Modern Trends in Physical and Material Chemistry) [Modern Trends in Physical and

Material Chemistry]





期間 Semester Spring 単位数 Number of Credits 1




Advanced Physical Chemistry, Catalytic Transformation, Photochemistry, Theoretical Chemistry, Chemical Energy Conversion, Separation

Process Engineering, Process Engineering, Catalyst Design, Analysis of Physical Properties of Materials, Nano-Photonics Materials, Inorganic

Solid State Chemistry, Mesoscopic Material Chemistry, Interfacial Electrochemistry, Physical Chemistry of Electronic Materials, Solid State

Chemistry of Functional Materials, Applied Inorganic Materials Chemistry


Lectures on scientific research in physical chemistry and materials chemistry will be given in English. In this course, the basic concepts and an

overview necessary for understanding the advanced research are introduced, followed by explanations of cutting-edge researches in various

fields of chemistry.


Through a series of lectures in various fields of chemistry in English, students will learn a broad perspective and an international sense in

chemical researches.


Lectures will be provided by young assistant and associate professors in the Graduate School of Chemical Sciences and Engineering. A

schedule of lecturers and titles will be informed in the first lecture of the course.


Assignment is required for every lecture.


It is required to attend at least 70% of the lectures. Evaluation as pass/fail will be based on the level of attendance (20%) and submitted reports

(each time, 80% in total).


なし。適宜資料を配布する。





科目名 Course Title 総合化学特論Ⅱ(Modern Trends in Organic Chemistry and Biological Chemistry) [Modern Trends in

Organic Chemistry and Biological Chemistry]









Structural and Physical Organic Chemistry, Macromolecular Science, Organometallic Chemistry, Physical Chemistry of Organic Materials,

Genetic Regulation, Disease Regulation, Synthetic Organic Chemistry, Biophisycal Chemistry, Biosynthetic and Metabolic Engineering,

Biosystem Engineering, Analytical Biochemistry, Functional Polymer, Cell Processing Engineering


Lectures on scientific research in Organic Chemistry and Biological Chemistry will be given in English. In this course, the basic concepts and

an overview necessary for understanding the advanced research are introduced, followed by explanations of cutting-edge researches in various

fields of chemistry.


Through a series of lectures in various fields of chemistry in English, students will learn a broad perspective and an international sense in

chemical researches.


Lectures will be provided by young assistant and associate professors in the Graduate School of Chemical Sciences and Engineering. A schedule

of lecturers and titles will be informed in the first lecture of the course.


Assignment is required for every lecture.



(each time, 80% in total).






科目名 Course Title 基礎物理化学特論 [Introductory of Physical Chemistry]



担当教員 Other Instructors Koichiro ISHIMORI(Faculty of Science), Tetsuya TAKETSUGU(Faculty of Science),

Satoshi MAEDA(Faculty of Science), Hiroshi TAKEUCHI(Faculty of Science)






Molecular orbital theory, Symmetry, Spectroscopy, Surface, Equilibrium and Kinetics


The purpose of this course is to understand the fundamental concepts of molecular orbital theory, symmetry, spectroscopy, surface, equilibrium

as well as kinetics in physical chemistry.


Goals are to develop skills to solve problems in physical chemistry and acquire the capacity how the knowledge is applied for chemical

application.


1. Molecular orbital theory （Atkins’ Physical Chemistry 8th edition, Chapter 11）

Molecular orbital theory, homonuclear diatomic molecules, chemical bonding

2. Molecular symmetry （Atkins’ Physical Chemistry 8th edition, Chapter 12）

The symmetry elements of objects, applications to molecular orbital theory and spectroscopy

3. Spectroscopy I: rotational and vibrational spectroscopy （Atkins’ Physical Chemistry 8th edition, Chapter 13）

General features of spectroscopy

4. Spectroscopy II: electronic transitions and Spectroscopy III：magnetic resonance （Atkins’ Physical Chemistry 8th edition, Chapter 14, 15）

The characteristics of electronic transitions, the fates of electronically excited states, the effect of magnetic fields on electrons and nuclei,

nuclear magnetic resonance

5. Processes at solid surfaces （Atkins’ Physical Chemistry 8th edition, Chapter 25）

Structure of solid surfaces, the extent of adsorption, heterogeneous catalysis, processes at electrode


To be announced.


The attitude at the lecture (30%) and report scores (70%) are evaluated.



Physical Chemistry 8th edition／Atkins：Oxford Press，2006




科目名 Course Title 無機化学特論 [Frontiers of Inorganic Chemistry]


責任教員 Instructor 小林厚志 [Atsushi KOBAYASHI] (Faculty of Science)







coordination chemistry, solid state chemistry, material chemistry, nano materials, nano science, photocatalysts, bioinorganic chemistry


The objectives of this course are: To understand the properties, structures, and functionalities of the coordination compounds which play

important roles in the various fields such as materials, bioinorganic chemistry, and nano science, To get the latest information of cutting-edge

research concerning inorganic and coordination chemistry.


The goal of this course is total understanding of the importance of coordination compounds from the viewpoints of coordination structures and

electronic states, and to develop the ability to predict structures, properties and (photo)reactivity of coordination compounds. At the same

time, students learn the sense of study in the fields of inorganic and coordination chemistry (typical concepts are listed below).

1) Ligand-field theory

2) Marcus Theory

3) Nano-science of coordination compounds

4) Importance of metal complexes in applied chemistry and biochemistry


(1) Basics and application of ligand-field theory

(2) Ligand exchange and electron transfer of metal complexes

(3) Photo-induced electron transfer and artificial photosynthesis

(4) Important effect of impurities ?in the cases of solar and fuel cells-

(5) Interesting properties of nano materials and porous materials


Exercise in Shriver & Atkins' Inorganic Chemistry (Oxford University Press)


Attendance (mini-exam, 30%), mid-term report (30%), and final exam (40%). More than 70% attendance is required to earn this credit.


シュライバー「無機化学」（下）第４版／田中、平尾、北川訳：東京化学同人，2008

Shriver & Atkins' Inorganic Chemistry／Peter Atkins：Oxford University Press，2010





科目名 Course Title 有機化学特論 [Special Lecture on Organic Chemistry]


責任教員 Instructor 谷野圭持 [Keiji TANINO] (Faculty of Science)

担当教員 Other Instructors Hajime ITOH(Faculty of Engineering)






basic organic chemistry, physical organic chemistry, organometallic chemistry, synthetic organic chemistry, polymer chemistry


This course aims to introduce participants to the latest trends and progresses in organic chemistry and related sciences. The class is opened

to the students who have not studied the specialized course of organic chemistry.


On completion of this course, students should be able to understand the recent trends and future problems in physical organic chemistry,

organometallic chemistry, synthetic organic chemistry, and polymer chemistry.


Lecture 1. Electroorganic synthesis

Lecture 2. Introduction to asymmetric reduction reactions

Lecture 3. New methods for functionalization of organic compounds: the boration approach

Lecture 4. How to understand the schemes of natural product synthesis

Lecture 5. The C-H--O hydrogen bond: the role and future in controlling the alignment of molecules

Lecture 6. Lessons from enzymes for designing chiral catalysts

Lecture 7. Nature's way to synthesize natural products: Comparison between chemical synthesis and enzymatic synthesis


While preparation is not required, students are expected to comprehend the lecture for preparing reports.



(twice, 40% each).


Textbooks are not assigned.





科目名 Course Title 基礎生物化学特論 [Introductory of Biological Chemistry]



担当教員 Other Instructors Akinori TAKAOKA(Institute for Genetic Medicine), Yasuyuki FUJITA(Institute for Genetic Medicine)






cell growth and differentiation, gene expression, epigenetics, signal transduction, oncogene, immunity, infectious disease


The class focuses on fundamental aspects of molecular mechanisms that underlie basic biological phenomena such as cell growth, cell

differentiation and immunity. In addition, how disorder of the regulatory mechanism causes diseases including cancer and infectious disease will

be discussed.


Students to be able to understand the basic regulatory mechanisms of gene expression, cell growth and immune system and developing

mechanisms for the related-diseases.


（１）Regulatory mechanisms for gene expression during cell differentiation： Transcription factor, Transcription factor network, Chromatin

structure

（２）Regulator mechanism of cell growth and senesence: cell growth signal, apoptosis and immortalization of the cell, oncogenes and tumor

suppressor genes in tumorigenesis

（３）Signal transductions in the host defense system: Signaling pathways to activate immune responses and molecular pathogenesis underlying

infectious diseases and immunodeficiency, cross-interaction between host and microbes


Students are expected to review the material provided by the instructors.


20%: class participation, 80%: examination



細胞の分子生物学第５版／B. Alberts 他：ニュートンプレス，2010

Molecular Biology of the Cell, the 5th edition／B. Alberts, et al.：Garland Science，2008




科目名 Course Title 分子物理化学特論 [Molecular Physical Chemistry]


責任教員 Instructor 佐藤信一郎 [Shinichiro SATOH] (Faculty of Engineering)







Quantum Mechanics, Perturbation Theory, Stark Effect, Zeeman Effect, Photoabsorption and Emission


Quantum theory is essential to understand molecular physical chemistry. The lecture is intended for graduate students who have a general

background in elementary quantum dynamics, and concentrates on the perturbation theory to give students a deep and essential understand

on the interactions between molecular system and external fields such as electric, magnetic, and photon fields.


By the end of the semester you should be able to:

-Apply the mathematical formalism of quantum mechanics to solve simple model problems.

-Analyze experiments that probe the quantum mechanical nature of matter to gain insight into the

structure and dynamics of atoms, molecules, and nanomaterials.


I. Steady-state perturbation theory: first-order perturbation theory including degenerate system and second-order perturbation theory

II. Stark effects of hydrogen atom: the first-order interactions for 2s, 2px, 2py, 2pz degenerate states and the second-order interaction for

1s state. The polarizability of hydrogen atoms will be discussed on the basis of the second-order perturbation theory.

III . Time-dependent perturbation theory

IV . Photoabsorption and emission processes will be discussed on the basis of time-dependent perturbation theory.


Students are requested to read relevant contents in the textbook beforehand: page ranges will be announced at

least in a week ahead.


Quiz and reports


現代量子化学の基礎／中島威藤村勇一：共立出版，1999




http://cma.eng.hokudai.ac.jp/index_english.html


科目名 Course Title 物質構造解析学特論 [Structural Analysis of Inorganic Materials]


責任教員 Instructor 忠永清治 [Kiyoharu TADANAGA] (Faculty of Engineering)

担当教員 Other Instructors Toshihiro SHIMADA(Faculty of Engineering), Yuji MASUBUCHI(Faculty of Engineering),

Akira MIURA(Faculty of Engineering)






x-ray structure analysis, electron microscope, neutron diffraction, X-ray absorption spectroscopy, solid-state NMR


Crystal structure analysis is required to understand the property of materials. X-ray, electron and neutron diffractions will be introduced for

the structural analysis especially in inorganic solids. Structural analysis of inorganic solids by X-ray absorption spectroscopy and solid-state

NMR will also be introduced.


X-ray diffraction theory will be introduced to understand the relation between crystal structure and electron density distribution. Electron

microscopy will also be applied for the analysis of inorganic materials. Neutron diffraction is useful to analyze the magnetic structure and the

position of light elements. The principle of X - ray absorption spectroscopy and the difference from the diffraction method will be discussed.

Structural analysis of inorganic materials using solid state NMR will be introduced.


1. What is x-ray? : Its generation, diffraction, scattering, absorption of x-ray etc.

2. X-ray diffraction for inorganic solids: powder diffractometor, qualitative and quantitative analyses, lattice parameter determination, crystallite

size and distortion, crystal orientation etc.

3. Neutron diffraction: Difference from x-ray diffraction.

4. X-ray absorption spectroscopy

5. Electron microscopy: Transmission, analytical and scanning electron microscopies for microstructure and electronic structure analysis.

6. Solid State NMR


Report submissions are required to apply structural analysis methods for the materials under investigation by each student.


Attendance of more than 70% of the lectures will be required for the evaluation. (1) report(20%) and (2) End of term examination (80%).



これならわかる X 線結晶解析これならわかる X 線結晶解析／安岡則武：化学同人，2000

セラミックスのキャラクタリゼーション技術：日本セラミックス協会



http://www.eng.hokudai.ac.jp/labo/strchem/

http://www.eng.hokudai.ac.jp/labo/kotai/

http://www.eng.hokudai.ac.jp/labo/inorgsyn/


Physical chemistry, Inorganic chemistry, Solid state chemistry and Inorganic materials chemistry are required.

科目名 Course Title 材料環境化学特論 [Corrosion Engineering]


責任教員 Instructor 安住和久 [Kazuhisa AZUMI] (Faculty of Engineering)







Metallic Materials; Complex Materials; Functional Materials; Corrosion Protection.


Degradation of materials used in many structures and functional devices is very important issue to sustain and develop our modern society.

Understanding the degradation mechanism, predicting the lifetime of materials, and suppressing the corrosion are therefore one of the major

subjects of engineering. In the lecture, theory of corrosion phenomena, examples of typical corrosion and degradation, strategies of corrosion

protection, development of degradation resistive materials, and evaluation methods of corrosion rate and lifetime will be introduced.


・Understanding the practical corrosion phenomena based on the physical chemistry

・Learning how to treat the corrosion-related phenomena quantitatively.

・Understanding the various engineering techniques applicable to various practical problems.


1. Introduction : Importance of corrosion phenomena and corrosion protection.

2. Theories in corrosion science : Local cell model of corrosion reaction, kinetics of electrode reaction, thermodynamics of the corrosion

phenomena and Paurbaix diagrams, concept of passivity, determination methods of corrosion rate including Tafel’s law, DC polarization method

and AC impedance method.

3. Classification of practical corrosion : Characteristics of uniform corrosion, galvanic corrosion, crevice corrosion, pitting corrosion, grain

boundary corrosion, selective corrosion, erosion corrosion, stress corrosion cracking, hydrogen embrittlement and high temperature corrosion.

4. Corrosive environments : Characteristics of various corrosion environment as moisture (water system), air, soil, concrete, (micro)bio-

system, dew point corrosion, corrosion in oil and natural gas, corrosion inside the electronic devices, and so on.

5. Corrosion protection : Corrosion resistive materials (characteristics of carbon steel, low-alloy steels, stainless steels, titanium, aluminum,

copper, and amorphous alloys), methodological approaches (coating, lining and inhibitors).


Students are expected to read text booklet before and after the lecture. Students are also required to put in a report for every lecture.


Reports (homework is given at each lecture) (60%), contribution to the discussion at the class (40%).


テキストは指定 Web サイトよりダウンロードする。


材料環境学入門／腐食防食協会編：丸善

腐食・防食ハンドブック／腐食防食協会編：丸善




Basic knowledge of thermodynamics and electrochemistry are required.

科目名 Course Title 生物資源化学特論 [Bioresources Chemistry]


責任教員 Instructor 惠良田知樹 [Tomoki ERATA] (Faculty of Engineering)







Biomacromolecules, Biodegradable polymer, Bio-related waste, Recycle technology


Biomacromolecules has been well known as the materials which compose the cells and tissues, and can be categorized as protein, nucleic acids

and polysaccharides. In this lecture offers the physical and chemical structure and properties of those macromolecules and how to utilize in

industry.


The general knowledge of the natural macromolecules such as protein, polypeptides, nucleic acids and polysaccharides from the structural and

functional points of view, not only the idea about those macromolecules but also the advanced analytical methods on the relatively complex

materials.


1. Basic idea of the bioresources and its categoraization.

2. Bioresource as the functional material.

3. Polysaccharides I: The structure and utilization of the Cellulose, starch

4. Polysaccharides II: The structure, function and utilization of the Chitin, Chitosan, Glycoaminoglycan and et al.

5. Structural protein: Collagen, Silk fibroin, Keratin.

6. Recycle technology of the biowaste (Food industry)

7. Recycle technology of the biowaste (Woods and pulp industry)

8. Nucleic acids and biotechnology.


The report and presentation about the journal article related on the lecture topic will be required from time to time.


Report and class participation.


適宜資料を配布する。参考書を適宜示すが，教科書は用いない。





科目名 Course Title 石油エネルギーの現状と未来 [Petroleum Energy: Present and Future]


責任教員 Instructor 清水研一 [Kenichi SHIMIZU] (Institute for Catalysis)








Oil supplies 54% of Japan's energy and most of the organic chemicals in industry. In this lecture, we understand the whole picture of the oil

industry that is the backbone of the energy industry and the chemical industry. We will learn development of fossil resources, petroleum refining,

production of fuels and lubricant, global warming, new energy and energy-saving technology.


Students will understand the whole picture of the oil industry. Towards the construction of a sustainable society, students will improve their

ability to discuss how the fossil resources should be used in Japan and in the world.


1. Introduction to industrial organic chemistry

2. Petroleum refining and fuel

3. Development of oil and natural gas

4. Global Warming

5. New Energy

6. Presentation by students

7. Presentation by students

8. Exam


It takes the time to prepare presentation files including answers to questions.


Number of the answers to the questions by the lecturer: 30%

Quality of presentation including answers to questions: 30%

Exam: 40%






科目名 Course Title 化学特別講義 [Advanced Chemistry]

講義題目 Subtitle 物理化学特別講義 2018 [Physical Chemistry 2018]

責任教員 Instructor 佐田和己 [Kazuki SADA] (Faculty of Science)

担当教員 Other Instructors 関修平（京都大学）

















講義題目 Subtitle 無機分析化学特別講義 2018 [Inorganic and Analytical Chemistry 2018]

責任教員 Instructor 日夏幸雄 [Yukio HINATSU] (Faculty of Science)

担当教員 Other Instructors 手塚慶太郎（宇都宮大学）

















講義題目 Subtitle 有機化学特別講義 2018 [Organic Chemistry 2018]

責任教員 Instructor 及川英秋 [Hideaki OIKAWA] (Faculty of Science)

担当教員 Other Instructors 内山真伸（東京大学）

















講義題目 Subtitle 生物化学特別講義 2018 [Biochemistry 2018]

責任教員 Instructor 坂口和靖 [Kazuyasu SAKAGUCHI] (Faculty of Science)

担当教員 Other Instructors 畠山昌則（東京大学）












特に指定しない


特に指定しない




科目名 Course Title 応用化学特別講義 [Advanced-Applied Chemistry]

講義題目 Subtitle 有機プロセス工学特別講義 2018 [Chemical Process Engineering 2018]

責任教員 Instructor 伊藤肇 [Hajime ITOH] (Faculty of Engineering)

担当教員 Other Instructors 矢貝史樹（千葉大学）

















講義題目 Subtitle 物質化学特別講義 2018 [Materials Chemistry 2018]

責任教員 Instructor 島田敏宏 [Toshihiro SHIMADA] (Faculty of Engineering)

担当教員 Other Instructors 中村雅一（奈良先端科学技術大学院大学）






organic semiconductor, charge transport, thermoelectric, energy harvesting, transistor, mobility,organic solar cells


Understand the charge transport in organic semiconductors and its application, focusing on the unified understandings from solid state physics

and molecular chemistry.


1. Quantum mechanics as a basic tool in semiconductors.

2. Physical properties of semiconductors and device applications. Principle of operation of transistors and carrier mobility.

3. Organic semiconductors.

4. Thin film devices and energy harvesting devices such as thermoelectrics.


1. Basics of semiconductors: from inorganic to organic

2. Organic semiconductors and their thin films

3. Energy harvesting devices based on thermoelectics

4. Organic semiconductors and thermoelectrics


No need for studying in advance. Homework will be instructed in the handout.


Evaluation is based on the participation attitude and final report.







講義題目 Subtitle 生物機能高分子特別講義 2018 [Advanced Applied Biochemistry 2018]


担当教員 Other Instructors 加地範匡（九州大学）












Lecture 時にプリントを配布します。






講義題目 Subtitle Leading and Advanced Molecular Chemistry and Engineering III - 2018

責任教員 Instructor 谷野圭持 [Keiji TANINO] (Faculty of Science)

担当教員 Other Instructors Akinori TAKAOKA(Institute for Genetic Medicine), Akira NAKAYAMA(Institute for Catalysis),

Takahiro SUZUKI(Faculty of Science), Atsushi MINAMI(Faculty of Science), Shinya TAKAHATA(Faculty

of Science), Tomohide SAIO(Faculty of Science), Hirokazu KOBAYASHI(Institute for Catalysis)






Biochemistry, Organic chemistry, Biosynthesis, Computational chemistry.


1) know mechanisms for the activation of cellular responses against microbial infection.

2) know computational chemistry with special emphasis on the first principles simulation.

3) know usefulness of heterogeneous catalyst for conversion of biomass.

4) know function of enzymes in biosynthesis of secondary metabolites.

5) know molecular mechanism of chromatin regulation in cell cycle.

6) know methodologies in synthetic organic chemistry for natural product synthesis.

7) know how proteins get their role through folding into native 3D structure.


By the end of this course you will be able to

1. understand importance of chemistry for searching principle of life in nature.

2. understand molecular mechanisms of various reactions in living cells.

3. understand progress of computional chemistry for predicting chemical reactions.

4. understand how to use chemical transformations for obtaining useful compounds.


June 11 a) Molecular mechanisms underlying host defense reponses

b) Recent advances in computational chemistry: first-principles simulation

June 12 a) Conversion of biomass by heterogeneous catalysts

b) Structural diversification of biologically active secondary metabolites

June 14 a) Promoter chromatin activation mechanism and gene expression

b) Natural product synthesis based on Diels-Alder reaction

June 15 a) Exploring the Chaperone Network in the Cell

b) discussion


None


You will be asked to write a page (A4) of essay on several lectures of your choice (60%).



No textbook required.






講義題目 Subtitle Leading and Advanced Materials Chemistry and Engineering I - 2018

責任教員 Instructor 佐田和己 [Kazuki SADA] (Faculty of Science)

担当教員 Other Instructors Akira KAKUGO(Faculty of Science), Mir Wais HOSSEINI（Universite de Strasbourg）






Molecular Machine, Molecular Assembly, Biomolecular Motors, Self-organization, Molecular Networks, Supramolecular Chemistry, Molecular

Tectonics, Gel, Nanoporous Materials, Crystals, Kinesin, Myosin, Dynein


Self-organization and complex system are key concepts for designing molecules and molecular assemblies toward emerged functions. This

course will provide fundamentals of chemistry of self-organization with respect to two different viewpoints; molecular machines and

supramolecular materials with molecular networks.

(I) Molecular Machines

The Nobel prize in chemistry 2016 was awarded to three chemists, Jean-Pierre Sauvage, Sir J. Fraser Stoddart and Bernard L. Feringa, for the

design and synthesis of molecular machines". The half of this course covers the fundamentals of molecular machines and bio-molecular motors.

The students will get a chance to come to know about: (1) basic information, (2) their working principle including mechanism of molecular

motions in highly integrated supramolecular structures, and biomolecualr motors, and (3) correlation between the molecular structure and

dynamic property. Furthermore, this course will focus on further applications of these molecular machines in relation to nanotechnology.

(II) Supramolecular Materials with Molecular Networks

The latter half part will focus on construction and properties of molecular-level network structures as supramolecular materials; lattice inclusion

compounds, porous coordination polymers, polymer gels, organo- or hydrogels from low-molecular-weight gelators. It will include (1) basic

information, (2) their designing principle, and (3) further integration for emerged functional materials. Some applications of all these materials

such as separation, catalysis, storage will be given.


This course reviews fundamentals of molecular machines including biomolecular motors and supramolecular materials with molecular network

structures. Students will be able to acquire basic knowledge both on preparation and molecular design and finally understand their construction

and working principle, and learn advanced their applications as material science.


(Topic I) Molecular machines

1. Introduction to molecular machines & macrocyclic compounds as hosts

2. Working principle and applications of molecular machines

3. Self-organization of bio-molecular motors

4. Working principle and applications of bio-molecular motors

(Topic II) Supramolecular materials with molecular networks

1. Introductory for molecules, information, and self-organization

2. Organic Self-assembled Systems with Pores; Molecular Tectonics

3. Chemically-crosslinked functional gels

4. Physical gels from small molecules


Students will read reviews and the primary literature on each topic, and submit questions for instructor after every classes and some written

reports on the topics.


Attendance more than 70% classes is requisite for evaluation of the credit.

The grade is evaluated in the following two items;(1) reports on each class with learning attitude (40%), (3) term examination or paper (60%).

Understanding for each class is evaluated by report or question and answer during the classes, and the basic knowledge for the subject is by

term examination or paper.


No textbook required. Handouts will be distributed.




http://complex-matter.unistra.fr/

http://wwwchem.sci.hokudai.ac.jp/~matchemS/index.html



講義題目 Subtitle Leading and Advanced Materials Chemistry and Engineering IIA - 2018


担当教員 Other Instructors Shuo HUANG（Nanjing University）






Single Molecule Methods, Bioanalytical Chemistry, Optics, Biosensors, Biophysics, Sequencing, Bio-imaging


The aim of the course will focus on how these technologies facilitates our understanding the mechamisms of biological activities in molecular

level and also how we can detect biological events of bio-analytical value (such as precision diagnoisis and disease curing). Besides that, this

course also helps the students to learn how to design innovative instruments for bio-analytical chemistry research at single molecule level.


By the end of this course you will be able to ;

1. understand the basic principle of biochemistry and genetics for the study of single molecule bio-analytical chemistry.

2. understand basic principle and state-of-art techniques in single molecule biosensing.

3. understand basic principles of optical microscopy, fluorescnece, instrumentation & programming.

4. design a novel single molecule biosensing instruments for specific scientific problems.


Lecture I: Fundamentals of Biochemistry & Genetics

Lecture II: Patch Clamp Technologies & Nanopore Biosensing

Lecture III: Single Molecule Imaging Techniques

Lecture IV: Single Molecule Force Spectroscopy

Seminar: Nanopore biophysics: from $1000 sequencing to single molecule biosensing


to be announced.


Your grade will be determined by how well you demonstrate your achievement of the course goals through

1. Daily course quizzes. 10%

2. Course discussions on specific topics. 40%

3. Short course proposal & presentation. 50%


Handouts will be distributed. (Single-molecule techniques : a laboratory manual, Paul R. Selvin, Taekjip Ha, ISBN: 087969775X)




http://wwwchem.sci.hokudai.ac.jp/pc/index.html

http://hysz.nju.edu.cn/bionano/index.html



講義題目 Subtitle Leading and Advanced Materials Chemistry and Engineering III - 2018

責任教員 Instructor 加藤昌子 [Masako KATO] (Faculty of Science)

担当教員 Other Instructors Hidenori NOGUCHI(NIMS), Akihiro OKAMOTO(NIMS)






Electrochemistry, Elecrtocatalisis, In situ surface probe, microbial extracellular electron transport (EET)


This course is designed to acquire basic knowledge in electrochemistry, such as electron transfer, electrocatalysist, microbial extracellular

electron transport (EET), and in situ surface probe techniques for the research in energy conversion.


Students will gain not only knowledge of electrochemistry, which form the basis of surface electrontrasfer which is important in energy conversion

materials. Also acquire problem-solving ability for exploring functionality of materials.


Course schedule is as follows:

(1) Basics of electrochemistry

(2) Electro transfer reaction, Electrocatalysis

(3) In situ surface characterization methods

(4) Protein electrochemical methods

(5) Microbial electrode catalysis

In FY2018, this course provides overviews of recent research on some topics from (1) to (5).


To read text books for electrochemistry at undergraduate level is highly recommended.


Assignment on a specified subject regarding to "Recent energy conversion systems at solid/liquid interface" (60%).







http://www.nims.go.jp/



講義題目 Subtitle Leading and Advanced Biological and Polymer Chemistry and Engineering I - 2018

責任教員 Instructor 坂口和靖 [Kazuyasu SAKAGUCHI] (Faculty of Science)

担当教員 Other Instructors Rui KAMADA(Faculty of Science), James G. OMICHINSKI（Universite de Montreal）






intrinsically disordered, protein-protein interactions, NMR, X-ray crystallography, post-translational modifications, acidic activation domains,

transcription, SUMO, SUMO-interacting motifs (SIM), PML-nuclear bodies, LC3, LC3-interacting region (LIR), autophagy; cancer, stress,

viral infections.


1) To establish the basics of the importance of intrinsically disordered protein regions in regulating dynamic biological processes.

2) To establish the correlation between an increase probability of post-translational modifications and intrinsically disordered protein regions.

3) To explain the special considerations that must be taken when preparing intrinsically disordered protein regions for structural

characterization.

4) To explain the limits of various structural biology techniques in characterizing intrinsically disordered protein regions.

5) To examine how intrinsically disordered protein regions can regulate the formation of dynamic complexes during transcriptional activation.

6) Highlight the flexibility of acidic activation domains in binding to transcriptional regulatory factors to regulate transcriptional activation and/or

repression.

7) To examine how intrinsically disordered protein regions regulate the transit of proteins in and out of PML-nuclear bodies function through

SUMO-SIM interactions.

8) Highlight how post-translational modifications regulate SUMO-SIM interactions in PML-nuclear bodies.

9) To examine how intrinsically disordered protein regions regulate autophagy through their role in regulate interactions with the LC3 family of

proteins.

10) Highlight how post-translational modifications regulate LC3-LIR interactions during autophagy.


1) To achieve an appreciation of what intrinsically disordered protein regions are and their role importance in regulating a wide range of cellular

processes through

their participation in dynamic protein-protein interactions.

2) To appreciate the tools and methods for structurally characterizing protein-protein complexes containing intrinsically disordered protein

regions.

3) To learn in detail about important processes where intrinsically disordered protein regions play key roles and why viral proteins often target

cellular functions regulated by intrinsically disordered protein regions.


Day 1: The role of intrinsically disordered protein regions in biological systems.

• Introduction and definition of intrinsically disordered protein regions.

• Relative occurrence in proteins as it relates to cellular functions.

• Functions and advantages for regulating biological systems.

• Relationship between intrinsically disordered regions and posttranslational modifications.

Day 2: Experimental methods for structurally characterizing interactions involving intrinsically disordered protein region.

• Special considerations for purifying intrinsically disordered protein regions.

• Advantages and disadvantage of various structural techniques.

• Characterizing intrinsically disordered protein regions using heteronuclear NMR spectroscopy.

Day 3: The role of intrinsically disorder protein regions in regulating transcription.

• Review the occurrence of intrinsically disordered protein regions in transcriptional regulatory factors.

• Discuss the role of transactivation domains (TADs) in regulating transcription and their connection to intrinsically disordered proteins regions.

• Present overview of how acidic TADs present in key transcriptional regulatory factors (such as p53, NF-kB, VP16) function through their

ability to form promiscuous protein-protein interactions.

• Discuss how many viral proteins that play a role in regulating host cell transcription contain intrinsically disordered protein regions.

Day 4: The key role of intrinsically disordered proteins regions in regulating cellular response to stress, cancer and viral infections.

• Review the factors that regulate the SUMOylation machinery.

• Discuss the role of SUMO-family proteins and SUMO-SIM interactions in regulating protein transit in and out of PML-nuclear body.

• Discuss how acetylation of SUMO proteins and phosphorylation of SIMs regulate SUMO-SIM interactions.

• Discuss the role of the of LC3-family protein and LC3-LIR interactions in regulating autophagy.

• Discuss how acetylation of LC3-family proteins and phosphorylation of LIRs regulate LC3-LIR interactions.


Scan through a few of the articles in the reading list


Assignment on a specified topic regarding "Structure determination of intrinsically disordered protein domains" or “Functional roles of

intrinsically disordered protein domains” (60%).




・Sigler PB. (1988) Nature 333:210-2. ・Wright PE, Dyson HJ. (2015) Nat Rev Mol Cell Biol. 16:18-29. ・Dyson HJ, Wright PE. (2016) J Biol

Chem. 291:6714-22. ・Babu MM. (2016) Biochem Soc Trans. 44:1185-1200. ・Staby L, O'Shea C, Willemoes M, Theisen F, Kragelund BB,

Skriver K. (2017) Biochem J. 474:2509-2532. ・Ahrens JB, Nunez-Castilla J, Siltberg-Liberles (2017) J. Cell Mol Life Sci. 74:3163-3174. ・

Birgisdottir AB, Lamark T, Johansen T. (2013) J Cell Sci. 126:3237-47. ・Lecoq L, Raiola L, Chabot PR, Cyr N, Arseneault G, Legault P,

Omichinski JG. (2017) Nucleic Acids Res. 45:5564-5576. ・Cyr N, de la Fuente C, Lecoq L, Guendel I, Chabot PR, Kehn-Hall K, Omichinski

JG. (2015) Proc Natl Acad Sci U S A. 112:6021-6. ・Cappadocia L, Mascle XH, Bourdeau V, Tremblay-Belzile S, Chaker-Margot M, Lussier-

Price M, Wada J, Sakaguchi K, Aubry M, Ferbeyre G, Omichinski JG. (2015) Structure 23:126-38. ・Krois AS, Ferreon JC, Martinez-Yamout

MA, Dyson HJ, Wright PE. (2016) Proc Natl Acad Sci U S A. 113:E1853-62. ・Iakoucheva LM, Radivojac P, Brown CJ, O'Connor TR, Sikes

JG, Obradovic Z, Dunker AK. (2004) Nucleic Acids Res. 32:1037-49. ・Huang R, Xu Y, Wan W, Shou X, Qian J, You Z, Liu B, Chang C,

Zhou T, Lippincott-Schwartz J, Liu W. (2015) Mol Cell. 57:456-66.



https://biochimie.umontreal.ca/en/department/professors/james-g-omichinski/

http://wwwchem.sci.hokudai.ac.jp/~biochem/index.html



講義題目 Subtitle Leading and Advanced Molecular Chemistry and Engineering I - 2018

責任教員 Instructor 伊藤肇 [Hajime ITOH] (Faculty of Engineering)

担当教員 Other Instructors Yoko YAMAKOSHI（ETH Zurich）






supramolecular chemistry, molecular recognition, non-covalent interaction


The objectives of this course are (i) developing a profound understanding of noncovalent bonding interactions and (ii) becoming prolific in the

most important synthetic methods applied to receptor syntheses.


Able to understand (1) the principle of molecular recognition principles, (2) synthetic strategy of artificial receptors and molecular machines,

and (3) supramolecular nanoscience / technological application.

Able to write synthetic strategy of supramolecular materials.


1. general principle of molecular recognition

2. cation and anion complex

3. complexation of neutral molecule, aromatic interaction

4. H-bonding, halogen-bonding, dipolar interaction

5. self-assembly and nanostructure, molecular machines


None


Students should provide a report.






http://www.yamakoshi.ethz.ch/

http://labs.eng.hokudai.ac.jp/labo/organoelement/



講義題目 Subtitle Leading and Advanced Molecular Chemistry and Engineering II - 2018


担当教員 Other Instructors Shih-Kang FAN（National Taiwan University）






digital microfluidics, microfluidic device, nanofluidic device, immunoassay, cell-based assay, MEMS


The course objective is to learn the basics and applications of DMF. It covers the principles of surface tension driven and electrically driven

microfluidics. The fabrication and design of the device and system will be introduced. Furthermore, the biomedical applications will be described.


The Couse goal is to illustrate the advances of electrically driven digital microfluidics (DMF). Class attendees would learn the principle, design,

and application of DMF.


Course title: Digital and Electric Microfluidics

1st lecture: Surface Tension and Microfluidics

Comparing to inertia and pressure, surface tension provides a more dominant force for liquid manipulations on a micro scale. The lecture focuses

on the basics of the surface tension and the means to alter surface tension including electrowetting. The lecture will cover the discovery of

electrocapillary, electrowetting, continuous electrowetting, and electrowetting-on-dielectric.

2nd lecture: Droplet-based Microfluidics and Digital Microfluidics (DMF)

Digital microfluidics (DMF) handles liquids in droplet forms. Different from emulsion-based droplet microfluidics, the droplets in DMF are

individually addressable. The lecture will introduce the droplet-based microfluidics including emulsion, DMF, and other mechanisms. The divide

fabrication, principle and design will also be described.

3rd lecture: Electrically-driven Microfluidics

The electrical forces are widely applied to alter surface tension and to realize DMF. Various electrically driven microfluidics will be addressed,

including electrophoresis, electro-osmosis, and dielectrophoresis. By combining electrowetting and dielectrophoresis, the lecture describes a

general electromicrofluidic platform manipulating (1) liquids with distinct electric conductivities, e.g., oil and water, (2) objects on variable scales

and phases, including solid particles, crosslinked microgels, liquid droplets, gas bubbles, and gaseous plasma, and (3) liquids in adjustable

geometries and formats, such as discrete droplets and continuous liquid columns.

4th lecture: Applications

In this lecture, several applications and varied configurations of DMF and electromicrofluidics will be covered. The commercial products of

DMF and electrowetting will also be introduced.

Seminar: 3D Heterogeneous Hydrogels Formation and Assembly on an Electromicrofluidic Platform

In this seminar, I will address the manipulations of prepolymer hydrogel droplets and cells on an electromicrofluidic platform to construct a

complex and heterogeneous microenvironment for cell culture. 3D hydrogel building blocks with reorganized cells or particles are formed and

assembled on the electromicrofluidic platform adopting electrowetting and dielectrophoresis.


None


Assignment on a specified subject regarding to "Digital Microfluidics and Microfluidic Devises" (60%).



Lecture notes will be provided.



http://fan-tasy.org/nanotascategory/news/

http://labs.eng.hokudai.ac.jp/labo/tokeshi_lab/



講義題目 Subtitle Leading and Advanced Materials Chemistry and Engineering IIB - 2018


担当教員 Other Instructors Taro NAGAHAMA(Faculty of Engineering), Rong TU（Wuhan University of Technology）






thin films, gradient materials, electronics, spintronics, ceramic, semiconductors, thermoelectricity, laser, vacuum


The modern life is impossible without using materials and chemical technology. In this course, we will shed light on the thin film and composite

materials, by inviting a leading researcher Prof. Rong TU from China. Now the thin film technology has reached to the level of controlling the

thickness of atomic layers. The emergence of nanomaterials which are synthesized by chemistry and various processing is now changing the

concept of composite materials. Your cellular phone is full of these technologies. We will explain the basic ideas behind the modern processes

and the fundamentals of the functions, including transparent conductors, solid state lasers, thermal insulation, ultrahard materials, various

sensing devices such as magnetic head of hard disk.

Prof. Rong TU had studied in Japan and has become a famous professor in China. He will explain how he studied and worked in the younger

days.



1. explain the basic concepts in electronics, spintronics, mechanical and thermal applications of thin films and composite materials.

2. explain the basic chemistry and physics behind the modern thin film technology and materials processing.

3. know how to study and work in overseas.


This course is focused on two subjects: materials processing and functions. In the materials processing part, we will provide three lectures and

one lab tour including

short demonstration experiments. The materials function part, we will provide four lectures. The course is organized as follows:

1. Introduction: How thin films and composite materials are used in the modern life.

2. Basic concepts behind the fabrication technology in atomic scales - interplay between the thermodynamics and kinetics, with the aid from

chemistry.

3. High energy processes:

4. Electronics and optical properties focusing on semiconductor circuits

5. Mechanical and thermal properties

6. Spintronics

7. Lab tour, showing plasma CVD, high pressure synthesis and various characterization techniques

8. Seminar by Prof. Rong TU.


It will be provided after each classes, if any.


Grading will be based on the final reports submitted some period after the lectures





http://sklwut.whut.edu.cn/english/




講義題目 Subtitle Leading and Advanced Materials Chemistry and Engineering IIC - 2018


担当教員 Other Instructors Yu-Lun CHUEH（National Tsing Hua University）






low dimensional materials, solar energy conversion, memory devices, sensors, semiconductors, nanotubes


Study on low dimensional nanomaterials is an emerging interdisciplinary field between chemistry and materials physics. The synthesis,

characterization, functionalization and device fabrication have become possible by recent development of nanotechnology. In this lecture, we

invite Prof. Yu-lun Chueh from National Tsinghua University, Taiwan, who is a leading young figure of atomic layer materials such as graphene,

MoS2, and applications on solar energy harvesting and memory devices. Nanomaterials have very unique electronic structures and full of

surfaces which can be chemically modified and functionalized. Various new concepts have been proposed and confirmed, and some have come

into practical applications. We provide basic view of this exciting research field.



1. explain the basic concepts in nanomaterials synthesis and functionalization, and device fabrication.

2. explain the basic chemistry and physics behind the application of nanomaterials.

3. know how to make international collaboration.


This course is focused on two subjects: synthesis of low dimensional nanomaterials and their functions. In the synthesis part, we will provide

three lectures and one lab tour including short demonstration experiments. The materials function part, we will provide four lectures. The

course is organized as follows:

1. Introduction: What are low dimensional nanomaterials?

2. Basic concepts of solid state chemistry and physics of low dimensional nanomaterials.

3. Synthesis techniques

4. Sensor and memory applications

5. Energy harvesting - basic concepts

6. Energy harvesting - application of low dimensional nanomaterials

7. Lab tour, showing equipment for nanomaterials synthesis and various characterization techniques

8. Seminar by Prof. Yu-lun Chueh


It will be provided after each classes, if any.


Grading will be based on the final reports requested to submit some period after the lecture.






http://nanoscienceandnanodevicelab.weebly.com/




講義題目 Subtitle Leading and Advanced Biological and Polymer Chemistry and Engineering II - 2018

責任教員 Instructor 佐藤敏文 [Toshifumi SATOH] (Faculty of Engineering)

担当教員 Other Instructors Takuya YAMAMOTO(Faculty of Engineering),

Moonhor REE（Pohang University of Science and Technology）






polymer chemical structure; polymer chain structure; polymer morphology; chain structure/morphology characterization methods; scatterings;

microscopies


This course provides the understanding on (i) polymer chain structure and its relations to chemical structure and synthesis history, (ii) polymer

morphology and its relations to chain structure and process history, and characterization skills of polymer chain and morphological structures.


Get knowledge on

(1) Polymer chain structure and its correlation to chemical structure and polymerization condition and pathway;

(2) A variety of polymer morphologies and their formation forces and their correlations to chain and chemical structures and process pathway;

(3) Characterization skills on polymer chain and morphological structures;

(4) The relationships of chain and morphology to polymer properties and applications.

Overall, build up background stronger in polymer physical chemistry (i.e., polymer physics).


1st lecture: Introduction to the correlations between chemical structure, chain structure, morphology, and properties of polymer

- Chemical composition; monomeric sequence; molecular weight; polydispersity index

- Chain structure characteristics

- Morphological structures

- Properties

2nd lecture: Polymer chain structure

- Monomeric unit sequence

- Stereoregularity; regioregularity

- Conformation

- Rigidity/flexibility

- Three-dimensional structure

- Characterization methods

3rd lecture: Polymer morphology in solid and in solution (I)

- Hierarchical structure in morphology

- Morphology representatives

- Driving forces of morphological structure formation

- Characterization methods

4th lecture: Polymer morphology in solid and in solution (II)

Seminar: Morphological Structures and Their Impacts on Properties of Functional Polymers in Various Topologies


None


Assignment on a specified subject regarding to "Structures and Their Correlations to Properties in Polymer Science".

We consider it as the important factor for assessment of three short tests (90%) and final report (10%).


Lecture notes in PDF files will be provided.


M. Ree, “Probing the Self-Assembled Nanostructures of Functional Polymers with Synchrotron Grazing Incidence X-Ray Scattering”,

Macromol. Rapid Commun. 2014, 35, 930-959



http://mree.postech.ac.kr/

http://poly-bm.eng.hokudai.ac.jp/mol/index.html


References suitable for this course:

(1) P.J. Flory, "Statistical Mechanics of Chain Molecules"

(2) R. J. Young,"Introduction to Polymers"

(3) G. Strobl, "The Physics of Polymers"

(4) H.-G. Elias, "An Introduction to Polymer Science"

(5) A. Tager, "Physical Chemistry of Polymers"

(6) L. F. Alexander, "X-Ray Diffraction Methods in Polymer Science"

(7) R.-J. Roe, "Methods of X-ray and Neutron Scattering in Polymer Science"

(8) G.H. Michler, "Electron Microscopy of Polymers"

(9) D.B. Williams and C.B. Carter, "Transmission Electron Microscopy"


講義題目 Subtitle Leading and Advanced Biological and Polymer Chemistry and Engineering III - 2018

責任教員 Instructor 大利徹 [Toru DAIRI] (Faculty of Engineering)

担当教員 Other Instructors Tomoki ERATA(Faculty of Engineering), Shinichiro SATOH(Faculty of Engineering),

Kenji TAJIMA(Faculty of Engineering), Hirofumi TANI(Faculty of Engineering),

Kenichiro MATSUMOTO(Faculty of Engineering)






Biochemistry, Bioluminescence, Chemiluminescence, Computational chemistry, Polymer chemistry, Biopolymer, Bacteria, NMR, Metabolic

pathway, Biopolymer.


1) understand biosynthesis of natural products.

2) understand how to use the spectroscopy on biological system.

3) understand bio- and chemiluminescence in analytical applications.

4) introduction of computational chemistry and its application to biochemistry and polymer chemistry.

5) understand biosynthesis and application of bacterial cellulose.

6) know basic of pathway and protein engineering and analytical methods.



1. simulate the biological engineering for production of useful compounds.

2. analyze the biopolymer such as bacterial cellulose with NMR spectroscopy.

3. design bio- and chemiluminescence reaction for chemical and biochemical analysis.

4. understand how to use computational chemistry in designing useful compounds.

5. design biopolymer-based materials.

6. understand the strategy to produce unnatural products.


June 25 a) natural product biosynthesis.

b) NMR spectroscopy for analysis on the structure and the metabolic pathway of bacterial cellulose.

June 26 a) production of nano-fibrillated cellulose using a cellulose-producing bacterium.

b) introduction of computational chemistry.

June 27 a) bio- and chemiluminescence in analytical chemistry.

b) basic of pathway and protein engineering and analytical methods.

June 28 discussion


None


Assignment on a specified subject regarding to "Biological Engineering Directed Production of Useful Chemicals" (60%).



No textbook required.






講義題目 Subtitle Polymers for Field-Effect Transistor Application

責任教員 Instructor 佐藤敏文 [Toshifumi SATOH] (Faculty of Engineering)

担当教員 Other Instructors Yu-Cheng CHIU（National Taiwan University of Science and Technology）
















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