Sensitif Skin

8/18/2019 Sensitif Skin

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Type I has been defined as the low-barrier function group

Type II has been defined as the inflammation group with normal barrierfunction and inflammatory changes.

Type III has been specified as the pseudo-healthy group in terms ofnormal barrier function and no inflammatory changes

a high content of nerve growth factor has been observed in the stratumcorneum, relative to that of non-sensitive skin. Both in Types II and III,the sensitivity to electrical stimuli was high. As these data suggest, the

hypersensitive reaction of sensitive skin is closely related to nerve fibersinnervating the epidermis.


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can be defined in both subjective and objectiveterms. ubjective perceptions of sensitive skinare derived from patient observations regardingstinging, burning, pruritus, and tightness,following various environmental stimuli. Becauseof the lack of clinical signs, the phenomenon ofsensitive skin is difficult to document. Attemptsto identify clinical parameters in subjects withsubjective irritation indicate that theseindividuals tend to have a less hydrated, less

supple, more erythematous, and moreteleangiectatic skin, compared with the normalpopulation. In particular, significant differenceswere found for erythema and hydration!dryness


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Appro"imately #$% of the population

consider themselves to possess the

characteristics of sensitive skin, and &$% of

these patients with sensitive skindemonstrate these uncomfortable symptoms

without accompanying visible signs of

inflammation '(&)

*asil test sering tidak konsisten

http://informahealthcare.com/action/showPopup?citid=citart1&id=ch1-B35&doi=10.3109/9781420004601.001http://informahealthcare.com/action/showPopup?citid=citart1&id=ch1-B35&doi=10.3109/9781420004601.001


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+cema

Atopic dermatitis

osacea

( componen

'/)kin barrier disruption

'0)Immune hiper reactivity

'()*eightened neurosensory response


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1haracteried by itching, stinging, burning,possibly pain

An intact stratum corneum cannot preventthe development of alergic contac dermatitisin sensitied individuals


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Type / pimples and comedo-acne

0 flushing-rosasea

( burning and stinging!itching

# impaired barier, contact and iritant dermatitis


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reactive to wide variety of both endogenand e"ogen factor 22very sensitif skin

1lear,dry, thin, with tendencyto blush!flush

reaction to environmental factor 22environmentaly sensitif

Transiently reactive to spesific and definablecosmetic product 222cosmetically sensitif

skin


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'/) +asily disrupted barrier function notaccompanied by a rapid!intense inflamatoryrespon 222 delicate skin

'0) strong inflamatory response without asighnificant increase in T+34 222reactiveskin

'() height-end neurosensory perception tominor cutaneous stimulation22 stingers


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condition of subjective cutaneous

hyperreactivity to environmental factors

many ingredients of cosmetics such as

dimethyl sulfo"ide, benoyl pero"ide

preparations, salicylic acid, propylene glycol,

amyldimethylamino-benoic acid, and 0-

etho"yethyl metho"ycinnamate


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*yperreactors may have a thinner stratum corneumwith a reduced corneocyte area, causing highertranscutaneous penetration of water-solublechemicals which makes these subjects moresusceptible to chemical irritation.

imbalance of intercellular lipid of stratum corneum

changes in the nerve system and!or the structure ofthe epidermis


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5ain tructural and 6unctional7roperties 8sed to tudy Barrier6unctiona

Sensitif Skin

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