Résonance Magnétique Nucléaire

Benjamin MARTY (b.marty@institut-myologie.org) Pierre CARLIER (p.carlier@institut-myologie.org)

Applications en imagerie médicale

Laboratoire de RMN AFM/CEA Institut de Myologie Bâtiment Babinski

Groupe Hospitalier Pitié-Salpêtrière Paris

RMN

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IRM

MR

MRI "spectro"

NMR

RMN

Spectro RMN

Spectro IRM

fMRI

MRS

NMRS

IRMf

H2O, CH2, CH3

1H NMR

NMR Imaging

NMR Spectroscopy

1H : myoglobin, creatine, lactate,

carnosine, acyl-carnitine

31P : ATP, Pcreatine, Pi, pH

23Na : viability

13C : glycogen, Krebs cycle

Anatomy

Morphometry

Lesion Detection

Staging r, T1, T2

v, f, D, T, h, k, c, d

Flow, Kinematics, Contractility

Perfusion

Diffusion, Temperature, viscosity

Chemical or Site exchange

Magnetic Environment, Chemical Moiety

Functional NMR Imaging

H2O, CH2, CH3

1H NMR

NMR Imaging

NMR Spectroscopy

1H : myoglobin, creatine, lactate,

carnosine, acyl-carnitine

31P : ATP, Pcreatine, Pi, pH

23Na : viability

13C : glycogen, Krebs cycle

Anatomy

Morphometry

Lesion Detection

Staging r, T1, T2

v, f, D, T, h, k, c, d

Flow, Kinematics, Contractility

Perfusion

Diffusion, Temperature, viscosity

Chemical or Site exchange

Magnetic Environment, Chemical Moiety

Functional NMR Imaging

Crosse de l’aorte

Tronc artériel brachio-

céphalique

Artère sous-clavière droite

Carotide primitive droite

Artère sous-clavière gauche

Carotide primitive gauche

Artère vertébrale gauche

Artère vertébrale droite

Carotide interne gauche

Carotide externe gauche

Carotide externe gauche et

ses branches

H2O, CH2, CH3

1H NMR

NMR Imaging

NMR Spectroscopy

1H : myoglobin, creatine, lactate,

carnosine, acyl-carnitine

31P : ATP, Pcreatine, Pi, pH

23Na : viability

13C : glycogen, Krebs cycle

Anatomy

Morphometry

Lesion Detection

Staging r, T1, T2

v, f, D, T, h, k, c, d

Flow, Kinematics, Contractility

Perfusion

Diffusion, Temperature, viscosity

Chemical or Site exchange

Magnetic Environment, Chemical Moiety

Functional NMR Imaging

Anatomy

Biochemistry

Physiology

# IMAGING

# FUNCTIONAL

IMAGING

# SPECTROSCOPY or

METABOLIC IMAGING

NMR