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7 PREFACE (( ..., cela ptut 2tre l'e'lectricite', le magnttisme ... Et, comme, il faut toujours proce'der du simple au compost, j'essaie en ce moment de faire cristalliser le race'mate dou- ble de soude et tl'ammoniaque sous I'inpuence d'une spirale sole'no'ide en activite'. ]'ai diverses autres formes d'exptrien- ces h tenter. Si l'une d'elles re'ussit, nous aurons du travail pour le reste de notre vie et dans Gn des plus grands sujets que l'homme puisse aborder, car je ne de'sespkre pas d'ar- river par-lh h unl= modification trks profonde, trks imprivue, extraordinaire des esp2ces animales et ve'ge'tales >>. PASTEUR (1871). Bioelectric interactions are p,itent in many biological processes but are difficult to understand. Complex experimental procedures are required ; however electric cellular activity underlying bone behavior is among the less understood tissue function. The guarantee of a rigorous approach is interdisciplinary cooperation because of the borderline situation of research involving the physical and life sciences. We began our application of electric stimulation to fracture healing in 1974. To obtain reliable results and to compare the effects of direct current or electromagnetic stimdation, a standard form with an accurate definition of the experimental procedure is a prime necessity. This form was proposed after the First European Symposium on Electric Stimulation of Bone Growth and Repair (. 976). Such a form should be adopted at the internatlional level. From the tremendous development in this new field of investigation during the last 20 years, it was possible to define a specific orientation of research : - Electric characteristics of living tissues. Acta Orthop Downloaded from informahealthcare.com by Lunds Universitet on 10/29/14 For personal use only.

Transcript of Preface

Page 1: Preface

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P R E F A C E

(( ..., cela p tu t 2tre l'e'lectricite', le magnttisme ... Et, comme, il faut toujours proce'der du simple au compost, j'essaie en ce moment de faire cristalliser le race'mate dou- ble de soude et tl'ammoniaque sous I'inpuence d'une spirale sole'no'ide en activite'. ]'ai diverses autres formes d'exptrien- ces h tenter. Si l'une d'elles re'ussit, nous aurons du travail pour le reste de notre vie et dans Gn des plus grands sujets que l'homme puisse aborder, car je ne de'sespkre pas d'ar- river par-lh h unl= modification trks profonde, trks imprivue, extraordinaire des esp2ces animales et ve'ge'tales >>.

PASTEUR (1871).

Bioelectric interactions are p,itent in many biological processes but are difficult to understand. Complex experimental procedures are required ; however electric cellular activity underlying bone behavior is among the less understood tissue function. The guarantee of a rigorous approach is interdisciplinary cooperation because of the borderline situation of research involving the physical and life sciences.

We began our application of electric stimulation to fracture healing in 1974.

To obtain reliable results and to compare the effects of direct current or electromagnetic stimdation, a standard form with an accurate definition of the experimental procedure is a prime necessity. This form was proposed after the First European Symposium on Electric Stimulation of Bone Growth and Repair ( . 976) . Such a form should be adopted at the internatlional level.

From the tremendous development in this new field of investigation during the last 20 years, it was possible to define a specific orientation of research :

- Electric characteristics of living tissues.

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- Spatial configuration of electric parameters induced by stimulating devices in living tissues.

- Celles sensors receiving electrical signals and their functional re- sponse.

- Bone response to Electric Stimulation.

W e are grateful to the members of the following departments for their help in our interdisciplinary research :

- Chaire de Construction, Ecole Royale Militaire (Prof. R. Bourgois).

- Dipartement de Chirurgie Osseuse, Hapita1 Brugman, Brussels Uni- versity (Prof. R. de Marneffe).

- Electro-Biology Inc. (Mr J. Ryaby).

- Institut de Recherche Interdisciplinaire en Biologie Humaine et Nucliaire, Brfussels University (Prof. J. Dumont) .

- Laboratoire d’Anatoniie et d’Embryologie Humaines, Brussels Uni- versity (Prof. J. Mulnard ) .

- Service << Analyse des contraintes D, Brussels University (Prof. J. Ebbeni).

- Service de Diagnostic par Isotope, Hapita1 Erasme, Brussels Uni- versity (D‘ A. Schoutens).

- Service de Radiologie, H8pital Erasme, Brussels University (D” J. Struyven).

L. Rybowski). - Service << Electricit4 Ginirale B, Brussels University (Prof.

- Service de Chirurgie Orthopidique et Traumatalogique, Hapita1 Saint-Louis (Prof. L. Sedel).

Maurice G. Hinsenkamp, M.D.

Franz Burny, M.D.,Ph.D.

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