Post on 03-Jul-2020
Journée annuelle de la recherche en ophtalmologie
2011
ProgrammeVendredi 3 juin 2011 7 h 45Salle Hydro-QuébecPavillon Desjardins, Université LavalQuébec (Québec)
27e
Nouveautés en glaucome à Québec.Où sommes-nous? Trabectome, SLT, suture transconjonctivale.Où pourrions-nous aller?
Dre Béatrice Des MarchaisCentre universitaire d’ophtalmologie, Hôpital du St-Sacrement, Centre hospitalier affilié universitaire de Québec (CHA); Département d’ophtalmologie, Faculté de médecine, Université Laval.
2011Vingt septième
2Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
3Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
Au terme de cette journée de la recherche, les participants :
!""#$%&'("")$')*+*,*)-)".",/"%$01$%01$"$'")/'(-2"%$01$%01$"+*&3-4*0/,$2"0,*'*56$2" " -7*4-3*&,&8*56$"$("3/*'(*$'4%&'("6'"*'(-%9("7&6%",/"%$01$%01$:!""#$%&'(";/3*,*/%*)-)"/<$0",/"3-(1&4&,&8*$"4$",/"%$01$%01$:!" =&6%%&'("4-<$,&77$%"4$)"1/+*,$(-)"4$"0&336'*0/(*&'")0*$'(*;*56$2"$'" " 7/%(*0*7/'("/6>"-01/'8$)")0*$'(*;*56$):!""#$%&'("$'"3$)6%$"4$";/<&%*)$%",/"0&336'*0/(*&'"$'(%$",/"%$01$%01$"0,*'*56$" " $(";&'4/3$'(/,$:!""=&6%%&'(";/*%$"6'$"/'/,?)$"0%*(*56$"4@6'$"76+,*0/(*&'")0*$'(*;*56$"$'"%$,/(*&'" " /<$0",/"<*)*&':!"A&''/B(%&'(",$)"4&''-$)"%-0$'($)"4$",/"%$01$%01$";&'4/3$'(/,$"$("0,*'*56$" " 7%&46*($"4/')",$6%"$'<*%&''$3$'(")6%",/";&'0(*&'"%-(*'*$''$2",/"CDEF2",$" " 8,/60&3$"$(",/"8-'-(*56$:!""=&6%%&'("*4$'(*;*$%",$)"($01'&,&8*$)"'&6<$,,$)"$(",$)"%-0$'()"4-<$,&77$3$'()" " 4/')",$)"3-(1&4$)"4*/8'&)(*56$)"$("01*%6%8*0/,$)2"$("$'"*'($%7%-($%",$)" " %-)6,(/()2",$)"/</'(/8$)2",$)"*'0&'<-'*$'():!" A&''/B(%&'(",$)"%-)6,(/()"4$)"%-0$'()"(%/</6>"4$"%$01$%01$"0,*'*56$"$(" " ;&'4/3$'(/,$")6%",$)"3/,/4*$)"4$",/"0&%'-$2",$"8,/60&3$2",/"'$6%&7/(1*$" " 0&37%$))*<$2",$"(%/*($3$'("4$",/"CEDF2",$"3-,/'&3$"&06,/*%$"G")&'" " (%/*($3$'("$(")&'"*'<$)(*8/(*&'2",$)"%-0$'()"4-<$,&77$3$'()"4$",/"01*%6%8*$" " 4$",/"0/(/%/0($2",@$;;$("4$)"HIJI")6%",$)"0$,,6,$)"&06,/*%$)2"$(",$)"6<-*($):!""F6%&'(",@&00/)*&'"4$"4*)06($%"$("4$"3$)6%$%",@*37/0("56$"7&6%%&'("/<&*%" " )6%",$6%"7%/(*56$"0$)"%-0$'()"4-<$,&77$3$'()"4/')",$"4&3/*'$"4$)" " 0&''/*))/'0$)I
A$(($"/0(*<*(-"$)("7/%%/*'-$"7/%",@F))&0*/(*&'"4$)"3-4$0*')"&71(/,3&,&8*)($)"46"K6-+$0I"
Objectifs de la journée de la recherche
4Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
7 h 45 Inscription, Café, Jus, Viennoiseries
8 h 10 Mot de bienvenue des Drs Béatrice Des Marchais, Nathalie Labrecque et Christian Salesse ainsi que du Dr Michel J. Tremblay, vice-doyen à la recherche et aux études supérieures, Faculté de médecine, Université Laval. " F371*(1-L(%$"M?4%&NK6-+$0
!"##$%&'#($"&)$*+,"
Modératrice " =/(%*0*/NF''"E/681%$/2"DC
8 h 20 Implication des médecins ophtalmologistes dans la recherche : le modèle français est-il intéressant? " O%-4$%*0"D&6%*/6>
8 h 45 -%./010$#%&'2"'34"5*(0($)6'2,'70&$8$9,.08'")'2,' ' :";0($9,.08'20&#'3"')10$)"."&)'2"'30'<=>?'"@#,20)$;"' selon une conduite thérapeutique individualisée. " A,/64*'$"P$,,$%*<$2"P$'&B("A*'5ND/%)2"Q*,,$)"E/,&'4$2"D/%*&" " D/,$';/'(2"R%*0"S&6%<*,,$2"T<&'"S/%4*;2"D/%0$,,$"Q*/))&'"$(" " D/%0"M-+$%(I"
9 h 00 Décompression latérale et médiane pour la neuropathie optique compressive dans l’orbitopathie dysthyroïdienne. " A/(1$%*'$"P/%*,2"T<&''$"D&,8/("$("C$'*)"=&6,*&(I
9 h 15 La suppression de l’expression du gène de la sous-unité !5 est intimement reliée aux propriétés tumorigènes de lignées cellulaires du mélanome uvéal. " D/%U&%*$"P$%8$%&'2"#&,/'8$"E/'4%$<*,,$2"O%/'V&*)"J*8'$/6,(2"" "" #($$<$"E$0,$%02"D/'&'"Q/64%$/6,(2"D&1*+"D&%0&)2"O%-4-%*0 " D&6%*/6>2"A1%*)(*/'"#/,$))$"$("#?,</*'""Q6-%*'I
9 h 30 Trabéculectomie et fermeture conjonctivale au limbe : résultats à long terme de la technique de Peng Khaw. Étude descriptive rétrospective. " =*$%%$"E$7/8$NE-(&6%'$/6"$("P-/(%*0$"C$)"D/%01/*)I
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5Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
9 h 45 Fréquence d’apparition de la délétion commune de l’ADN mitochondrial dans les yeux humains. " #-+/)(*$'"Q$'4%&'"$("=/(%*0W"XI"Y&01$(($I
10 h 00 Mosaïcisme pigmentaire cutané et d’autres tissus : présentation oculaire atypique avec pressions intra-oculaires élevées. " Z/%&,*'/"A13*$,$[)W/2"=/(%*0W"M/3$,"$("C/'*$,,$"D/%0&6>I"
10 h 15 A0,#"B(056'")'#60&("'2405*(C"#
" \I""]>7%$))*&'2"76%*;*0/(*&'"$(",*/*)&'"3$3+%/'/*%$"4$)"%-(*'&,)" " " 4-1?4%&8-'/)$)"^"$("\\I""" " R,&4*$"P&*))$,*$%2"D/%*$NE&6"F64$(2"D/%*&"D-(1&(2"E*'$"A/'(*'"""" " $("A1%*)(*/'"#/,$))$I"
" _I""Y-86,/(*&'"4$",@/0(*<*(-"46"7%&3&($6%"46"8`'$"a!b"4$",@*'(-8%*'$" " a" !5 "\"7/%",$"0&,,/8`'$"4/')",$)"0$,,6,$)"-7*(1-,*/,$)"4$",/"0&%'-$I""" " X$''*;$%"E/W$2"#($$<$"E$0,$%02"=/(%*0W"A/%%*$%2"E60*$"Q$%3/*'2" " " A1%*)(*/'"#/,$))$"$("#?,</*'"Q6-%*'I"
" cI"d'($%/0(*&'"3$3+%/'/*%$"4@6'$"'$6%&7%&(-*'$")$')*+,$"/6"0/,N " " 0*63"efA#g2",/"%$0&<$%*'$"G"R(64$"7/%")7$0(%&)0&7*$"4$"%-)&N " " '/'0$"3/8'-(*56$"'60,-/*%$"eYDfg"$("*';%/%&68$"eOSNdYgI" " Q$'$<*`<$"J/,&*)N=/*,,/%42"=1*,*77$"A/,<$h2"A1%*)(*/'"#/,$))$2" " " D*01`,$"F68$%I
10 h 35 Intérêt de la thermothérapie transpupillaire (TTT) isolée dans le traitement des naevi choroïdiens suspects." #-+/)(*$'"S6%0&(($2"C/'"P$%8$%&'2"F,/*'"Y&6))$/6"$(" " O%-4-%*0"D&6%*/6>I
10 h 50 Analyse des dommages induits par les rayons UVB à l’ADN des cellules du segment antérieur de l’œil. " X6)(*'"D/,,$("$("=/(%*0W"XI"Y&01$(($I
11 h 05 >"'D"%.$&EF'"#)B$3'0,)0&)'"5*(0("'+,"'3"':%)%@E'/%,1' le traitement du blépharospasme essentiel bénin? " X6,*$'"#//4"$("F,/*'"Q&6%4$/6I
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6Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
11 h 20 Conférence de la Fondation des maladies de l’oeil : Nouveautés en glaucome à Québec. Où sommes-nous? Trabectome, SLT, suture transconjonctivale. Où pourrions- nous aller? " P-/(%*0$"C$)"D/%01/*)2"DC" A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2" " A$'(%$"1&)7*(/,*$%"/;;*,*-"6'*<$%)*(/*%$"4$"K6-+$0"eAMFg:"C-7/%($N " 3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
12 h 20 Dîner " #/,,$"j"E$"A$%0,$"k2"le"-(/8$2"=/<*,,&'"C$)U/%4*')" #-/'0$"4@/;;*01$)
!"##$%&'#($"&)$*+,"
13 h 35 Cornée, version Toronto Western Hospital " D/%*$"]<$"E-8/%-
13 h 50 -01)%G10/C$"'2"#'GH&"#'.%2$*(0)",1#'2"'30'#6;61$)6'2,' glaucome à angle ouvert. " =/)0/,"P$,,$/62"#(-71/'$"C6+&*)2"Z/%*'$"E$+$,2"Y&)$"F%)$'$/6,(2"" " X$/'NE&6*)"F'0(*,2"R%*0"#1*'W2"Q*,,$)"Ai($2"D/%0$,"F3?&(2"Y-)$/6" " Q,/60&3$"K6-+$0"$("J*'0$'("Y/?3&'4I"
14 h 05 762,()$%&'2"'30'+,0&)$)6'2"'(%1)$(%#)61%I2"')%/$+,"'&6("#B saire dans le traitement de l’uvéite antérieure aiguë par ' 3402J%&()$%&'24,&'0&)$B$&K0..0)%$1"'&%&'#)61%I2$"&')%/$+,"L''" J/,-%*$"Q%&'4*'"$("=*$%%$"C686/?I"
14 h 20 Faut-il continuer à demander un bilan hépatique pour détecter les métastases hépatiques dans le mélanome de la choroïde ? " O%-4-%*0"D&6%*/6>2"A/%&,*'$"C&%*&2"C/'""P$%8$%&'2"D/%(1$" " D$%0*$%"$("F,/*'"Y&6))$/6I"
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7Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
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14 h 35 M./0()'2"'2$5561"&)#')N/"#'2"')10$)"."&)'0&)$B$&K0..0)%$1" post-trabéculoplastie au laser sélectif sur la tension ' $&)10%(,30$1"'(C"9'3"#'/0)$"&)#'0))"$&)#'2"'G30,(%."' primaire à angle ouvert. " d)/+$,,$"F60&*'2"#&71*$"A1/37/8'$2"m,*<*$%"E/)'*$%2"X$/'NE&6*)" " F'0(*,2"F''*$"Q&?$(($2"A/%&,*'$"E/U&*$2"D/%*$NX&)-$"O%$4$(($"$(" " P-/(%*0$"C$)"D/%01/*)I"
14 h 50 O@$#)"B)B$3',&"'P'-03($,.'.N1$#)%N3'#Q$)(C'R'(C"9'30'S-?ABTU''" =1*,*77$"A/,<$h"$("A1%*)(*/'"#/,$))$I"
15 h 05 M&5%1.0)$%&#'7O-7VWO=OXW'Y'A1%J")#'2"'1"(C"1(C"'"&'(%,1#L'
15 h 10 A0,#"B(056'")'#60&("'2405*(C"#
15 h 30 Un Fellowship en pathologie oculaire : Son rôle dans l’activité de routine et dans la recherche. " D&1*+"D&%0&)"
15 h 45 Les facteurs de risque d’une fuite de bleb après une trabéculectomie : une étude descriptive rétrospective de type cas-témoins. " Z/%&,*'/"A13*$,$[)W/"$("P-/(%*0$"C$)"D/%01/*)I"
16 h 00 L’utilisation de lentilles intraoculaires (LIO) pliables suturées à la sclère en cas d’absence de support capsulaire et ' 9%&,30$1"'026+,0)Z'/C0#"'[L''" D/>*3$"E/%&01$2"D/%*$"]<$"E-8/%-"$("Y$'-"C*'1I"
16 h 15 Fin des présentations et délibération du jury
19 h 00 -%(\)0$3'")'!%,/"1']'7"#)0,10&)'?A!?7?'" n\2"Y6$"4@F6($6*,2"K6-+$0"eK6-+$0g"Q\Y"lAc" Y$3*)$"4$)"7%*>"4@$>0$,,$'0$"4$)"7%-)$'(/(*&')"$("/6(%$)"7%*>" " 4$";*'"4@/''-$"7$'4/'(",/")&*%-$I
8Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
Christian Salesse, PhD" " C*%$0($6%"4$",/"%$01$%01$" " " " =%-)*4$'("4$",/"U&6%'-$"/''6$,,$"4$" " " " " ,/"%$01$%01$"$'"&71(/,3&,&8*$ AC$3$//"'-03;"9F'=!(" " R(64*/'("/6"4&0(&%/( ^..0&,"33"'-C03$5%,@F'7_" Y-)*4$'($"$'"&71(/,3&,&8*$" Béatrice Des Marchais, MD" C*%$0(%*0$"/4U&*'($".",/"%$01$%01$"0,*'*56$" " " " A1$%01$6%$"0,*'*0*$''$"/))&0*-$ =01("33"'S$0##%&F':!(" " A&&%4&''/(%*0$"4$",/"%$01$%01$"0,*'*56$ Patricia-Ann Laughrea, MD" =%&;$))$6%$"/8%-8-$"" " " " C*%$0(%*0$"4$",/"+/'56$"4@?$6> ?30$&'7%,##"0,F'=<" " =%&;$))$6%"-3-%*($" " " " A1$%01$6%"0,*'*0*$'"/))&0*-
Comité organisateur
9Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
1986 Dr'7%8"1)'AL'=,1/CN"" " P/,(*3&%$
1987 Professeur Henry Hamard"" =/%*)2"O%/'0$
1988 Dre':1"&20'>L'S033$""" " H'*<$%)*(-"4$"S&%&'(&
1989 Dr John Marshall " " H'*<$%)*(-"4$"E&'4%$)
1990 Dr Alan Cruess"" " " H'*<$%)*(-"4$"Z*'8)(&'
1991 Dr'?30$&'7%,##"0,"" " H'*<$%)*(-"E/</,
1992 Dr'S10C0.'W1%/"" " H'*<$%)*(-"4$"S&%&'(&
1993 Dre Hélène Boisjoly"" " H'*<$%)*(-"E/</,
1994 Dr'`302$.$1'a%,9%,#"\"" " H'*<$%)*(-"C/,1&6)*$
1995 Dr Christian Salesse"" " H'*<$%)*(-"E/</,
1996 Dr Jean Deschênes"" " H'*<$%)*(-"D0Q*,,
1997 Dr'!N3;0$&'S,61$&""" " H'*<$%)*(-"E/</,
1998 Dr Ian McDonald " " H'*<$%)*(-"4@F,+$%(/
1999 Dr Pierre Turcotte"" " H'*<$%)*(-"E/</,
2000 Dr Christian Hamel"" " df#]YD2"O%/'0$
2001 Dr'`$&("&)'70N.%&2"" " H'*<$%)*(-"E/</,
2002 Dre'>,($"'S"1.0$&"" " H'*<$%)*(-"E/</,
2003 Dr Yves Pouliquen"" " =/%*)2"O%/'0$
2004 Dr Marc Hébert"" " " H'*<$%)*(-"E/</,
2005 Dre'b%C0&&"'7%8$)0$33""" " H'*<$%)*(-"C/,1&6)*$
2006 Dr'7$(C012':09$&"" " H'*<$%)*(-"E/</,
2007 Dr William Harbour"" " H'*<$%)*(-"4$"o/)1*'8(&'"""" " " " " " D*))&6%*
2008 Dre Marie-Josée Fredette"" H'*<$%)*(-"E/</,
2009 Dr Yves Fradet"" " " H'*<$%)*(-"E/</, Dr Yvon Cormier"" " H'*<$%)*(-"E/</,
2010 Dre Yvonne Buys " " H'*<$%)*(-"4$"S&%&'(&
2011 Dre Béatrice Des Marchais " H'*<$%)*(-"E/</,
Conférenciers invités de la journée de la recherche
10Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
?&&6"'' ' ' 76#$2"&)#c"#d
\p^b" " " N\p^q" " " =*$%%$"S6%0&(($\p^n" " " A,/64$"D-'/%4\p^^" " " f/(1/,*$"E/+%$056$\p^p" " " E60"J/*,,/'0&6%(\ppr" " " C/'"P$%8$%&'\pp\" " " Y&8$%"D&%*))$(($\pp_" " " X&1/''$"Y&+*(/*,,$\ppc" " " P-/(%*0$"C$)"D/%01/*)\ppl" " " C/'*$,"P,/0W\ppb" " " Y$'-"C*'1\ppq" " " ]68`'$"M,/4W?\ppn" " " A1/'(/,"C$,&%3$\pp^" " " E60*$"Z1&6%*\ppp" " " E60*$"Z1&6%*2"F,/*'"Q%-8&*%$2"F''*$"Q&?$(($_rrr" " " D/%*$NX&)-$"O%$4$(($_rr\" " " S1/&"f86?$'_rr_" " " D/%*$NX&)-$"O%$4$(($_rrc" " " R%*0"S&6%<*,,$_rrl" " " T/''*W"P&6(*'_rrb" " " D-,*))/"E&6*)_rrq" " " F,/*'"E/7,/'($12"C/<*4"A1$<%$(($2
Problématique Étude de cas Projet terminé
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11Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
Année Étudiants(es) aux cycles supérieurs
\p^b" " " N\p^q" " " N\p^n" " " N\p^^" " " #(-71/'*$"P$%'/(01$h\p^p" " " #(-71/'*$"P$%'/(01$h\ppr" " " C$'*)"#&6,*`%$)\pp\" " " R%*0"o/8'$%\pp_" " " D/'&'"S/%4*;\ppc" " " D*01`,$"X/0&+\ppl" " " A1/'(/,"C$,&%3$" " " D*01`,$"X/0&+\ppb" " " Z/(1?"E/%&601$\ppq" " " f*0&,/)"E/%&601$\ppn" " " F,/*'"P-,*<$/6\pp^" " " #(-71/'*$"=%&6,>\ppp" " " Z/(1?"E/%&601$_rrr" " " =/(%*0W"A/%%*$%_rr\" " " F,$>/'4%$"C$)01/3+$/6,(_rr_" " " #(-71/'*$"=%&6,>_rrc" " " D-,/'*$"P-%6+-_rrl" " " #(-71/'*$"Q&+$*,_rrb" " " F''$"Y6;*/'8$_rrq" " " D/%*$Ns<$"Q*'8%/)1
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1er cycle 2e cycle 3e cycle
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12Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
A1%*)(*/'"#/,$))$2"=1C" " =%-)*4$'(" " " " Em]t"u"AHm"v"%$01$%01$" " " " A$'(%$"4$"%$01$%01$"46"AMF" " " " " Mi7*(/,"46"#(N#/0%$3$'("eAMFg" " " " O/06,(-"4$"3-4$0*'$" " " " H'*<$%)*(-"E/</,
P-/(%*0$"C$)"D/%01/*)2"DC" A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$" " " " Mi7*(/,"46"#(N#/0%$3$'("eAMFg" " " " C-7/%($3$'("4@&71(/,3&,&8*$"" " " " O/06,(-"4$"3-4$0*'$" " " " H'*<$%)*(-"E/</,
T<&''$"D&,8/(2"DC" " A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$" " " " Mi7*(/,"46"#(N#/0%$3$'("eAMFg"" " " " C-7/%($3$'("4@&71(/,3&,&8*$"" " " " O/06,(-"4$"3-4$0*'$" " " " H'*<$%)*(-"E/</,
O%-4-%*0"D&6%*/6>2"DC2"=1C" Em]t"u"%$01$%01$"" " " " A$'(%$"4$"%$01$%01$"46"AMF" " " " Mi7*(/,"46"#(N#/0%$3$'("eAMFg" " " " C-7/%($3$'("4@&71(/,3&,&8*$"" " " " O/06,(-"4$"3-4$0*'$" " " " H'*<$%)*(-"E/</,"$( " " " " C-7/%($3$'("4@&71(/,3&,&8*$" " " " A$'(%$"1&)7*(/,*$%"6'*<$%)*(/*%$"4$"A/$' France
Membres du jury
13Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
J*'0$'("Y/?3&'42"DC2"=1C" E/+&%/(&*%$"4$"8-'-(*56$"3&,-06,/*%$" " " " " 4$)")?)(`3$)")$')&%*$,)" " " " A$'(%$"4$"%$01$%01$"46"AMHK" " " " A$'(%$"1&)7*(/,*$%"4$",@H'*<$%)*(-"E/</,"""""""" "" " " " eAMHEg"$("AY]DmQM""" " " " C-7/%($3$'("4@&71(/,3&,&8*$" " " " O/06,(-"4$"3-4$0*'$" " " " H'*<$%)*(-"E/</,
R%*0"S&6%<*,,$2"DC"" " A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$" " " " " Mi7*(/,"46"#(N#/0%$3$'("eAMFg" " " " C-7/%($3$'("4@&71(/,3&,&8*$"" " " " O/06,(-"4$"3-4$0*'$" " " " H'*<$%)*(-"E/</,
Modératrice :
=/(%*0*/NF''"E/681%$/2"DC" A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$" " " " " Mi7*(/,"46"#(N#/0%$3$'("eAMFg"" " " " C-7/%($3$'("4@&71(/,3&,&8*$"" " " " O/06,(-"4$"3-4$0*'$" " " " H'*<$%)*(-"E/</,
Membres du jury
14Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
15Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
76#,.6#des 0&
336'*0/(*&')
16Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
8 h 20
Implication des médecins ophtalmologistes dans la recherche : le modèle français est-il intéressant?
Frédéric Mouriaux
Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
C-7/%($3$'("4@&71(/,3&,&8*$2"A$'(%$"1&)7*(/,*$%"6'*<$%)*(/*%$"4$"A/$'2"O%/'0$I
]'"(/'("56$"01$%01$6%"0,*'*0*$'"$'"/''-$")/++/(*56$"/6"AMF"/6"K6-+$0"4-(/01-"4$"3&'"7&)($"/6"AMH"4$"A/$'"$'"O%/'0$2"U@/*"<&6,6"."(%/<$%)"0$("$>7&)-"7%-N)$'($%",/"4?'/3*56$"46")?)(`3$"4$"8$)(*&'"4$",/"%$01$%01$"$;;$0(6-$"$'"O%/'0$"7/%" ,$)"3-4$0*')")-'*&%)"ej7/(%&')kg"/*')*"56$"7/%" ,$)"3-4$0*')"$'";&%3/(*&'"ej%-)*4$'()kgI"X@$>7&)$%/*"4&'0"G
" !" E$"06%)6)"'-0$))/*%$"7&6%"9(%$"3-4$0*'"1&)7*(/,*$%"6'*<$%)*(/*%$"$("'&'" " " 6'*<$%)*(/*%$"$'"O%/'0$"$(",@-</,6/(*&'"4$",/"7%&460(*&'")0*$'(*;*56$"4$)" " " 6'*<$%)*(/*%$):
" !" E$)"3&?$')";*'/'0*$%)"4-<&,6)"/6>"3-4$0*')")-'*&%)"$("/6>"3-4$0*')" " " $'";&%3/(*&'"7&6%";/*%$"4$",/"%$01$%01$:
" !" E@-</,6/(*&'" 4$)" 3-4$0*')" $'" ;&%3/(*&'" 4/')" ,/" </,*4/(*&'" 4$" ,$6%" " " 4*7,i3$"4$")7-0*/,*)($:
" !" E$)"3&4$)"4$";*'/'0$3$'()"</%*/+,$)"4$)"1i7*(/6>"e#dQF=#"$("#dQY]Ag" " " $(",$6%)"*37,*0/(*&')"$'"($%3$"4$"%$01$%01$I
S&6)"0$)"-,-3$'()"0&'0&6%$'("."6'$"4?'/3*56$"7&)*(*<$"4$"%$01$%01$I"d,"7&6%%/*("9(%$"*'(-%$))/'("4@-</,6$%")*"0$"3&4`,$"7&6%%/*("9(%$"/77,*0/+,$"/6"K6-+$0"4/')",@&+U$0(*;"4$")(*36,$%",/"%$01$%01$"0,*'*56$"01$h",$)"3-4$0*')I
17Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
e'C'_f
-%./010$#%&'2"' 34"5*(0($)6'2,'70&$8$9,.08'")'2,':";0($9,.08'20&#' 3"'traitement de la DMLA exsudative selon une conduite thérapeutique indi-vidualisée
Claudine Bellerive12"P$'&B("A*'5ND/%)\2_2c2"Q*,,$)"E/,&'4$\2_2c2"D/%*&"D/,$';/'(32"R%*0"S&6%<*,,$\2_2c2"T<&'"S/%4*;\2_2c2"D/%0$,,$"Q*/))&'\2_"$("D/%0"M-+$%(\2_2l 1 A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI2 C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I3 A$'(%$"&06,/*%$"4$"K6-+$02"K6-+$0I"4 A$'(%$"4$"%$01$%01$"H'*<$%)*(-"E/</,"Y&+$%(NQ*;;/%42"d')(*(6("6'*<$%)*(/*%$"$'")/'(-"3$'(/,$"4$"" """K6-+$02"A$'(%$"1&)7*(/,*$%"/;;*,*-".",@H'*<$%)*(-"E/</,I
Contexte et objectifs :"=,6)*$6%)"-(64$)"0,*'*56$)"36,(*0$'(%*56$)"&'("4-3&'N(%-"56$",@/43*'*)(%/(*&'"3$')6$,,$"4@*'U$0(*&')"*'(%/<*(%-$''$)"4$"Y/'*+*h63/+")6%"6'$"7-%*&4$"4@6'"/'"$)("6'" (%/*($3$'("$;;*0/0$"7&6%" ,/"'-&</)06,/%*)/(*&'"%$(%&6<-$"4/')",/"CDEFI"S&6($;&*)2",/";%-56$'0$"4@*'U$0(*&')"7&6%",@&+($'(*&'"4$"%-)6,(/()"<*)6$,)"&7(*3/6>"'@$)("7/)"/0(6$,,$3$'("-(/+,*$I"H'$"($'4/'0$"&+)$%N<-$"/67%`)"4$)"&71(/,3&,&8*)($)"/;*'"4$"%-46*%$",$"'&3+%$"4@*'U$0(*&')"%$56*)$)"0&')*)($"$'"6'"%-8*3$"4$"(%/*($3$'("*'4*<*46/,*)-I"A1/56$"7/(*$'("%$V&*("*'*(*/N,$3$'("c"*'U$0(*&')"3$')6$,,$)"4$"Y/'*+*h63/+"&6"4$"P$</0*h63/+")6*<*"4@6'$")-56$'0$"</%*/+,$"4@*'U$0(*&')"4-($%3*'-$"7/%",$)"%-)6,(/()"&+($'6)".",@mAS"$(".",@/'8*&8%/71*$"/*')*"56$"7/%",@-<&,6(*&'"0,*'*56$I"E@&+U$0(*;"4$"0$(($"-(64$"$)("4@-</,6$%",@$;;*0/0*(-"46"Y/'*+*h63/+"$("46"P$</0*h63/+")$,&'"6'"7,/'"4$"(%/*N($3$'("/4/7(-"."01/56$"7/(*$'(I"
Matériel et méthodes :"d,")@/8*("4@6'$"-(64$"%-(%&)7$0(*<$:"qbl"4&))*$%)"4$"7/N(*$'()"/?/'("%$V6"4$)"*'U$0(*&')"4$"Y/'*+*h63/+"&6"4$"P$</0*h63/+"$'(%$"U6*'"_rrq"$("4-0$3+%$"_rrp"&'("-(-" %-<*)-)"/6"A$'(%$"m06,/*%$"4$"K6-+$0I"#$6,)",$)"7/(*$'()"/<$0"6'"4*/8'&)(*0"4$"CDEF"$>)64/(*<$"e7%-4&3*'/'0$"0,/))*56$2"3*'*3/,$3$'("0,/))*56$"$("&006,($g"&'("-(-"*'0,6)"4/')",@-(64$I"E$"01/'8$3$'("&6",@/44*(*&'"4@6'"(%/*($3$'("$'"0&6%)"4$")6*<*"/*')*"56$",/"7%-)$'0$"4$"(%/*($N3$'()"7%-0-4/'("0$,6*"-(64*-"0&37($'("7/%3*" ,$)"7%*'0*7/6>"0%*(`%$)"4@$>0,6N)*&'I"E$)"4&''-$)"0,*'*56$)"%-0&,(-$)"0&')*)($'("$'",@FJ"7%-"$("7&)("*'U$0(*&')"/6"0&6%)"4@6'")6*<*"4@6'$"46%-$"4$"\"/'"/*')*"56$",$"'&3+%$"4@*'U$0(*&')"%$V6$)"7/%"7/(*$'(I"E@FJ"/"-(-"3$)6%-$".",@/*4$"4$",/"01/%($"#'$,,$'"$(",$)"4&''-$)"&'("-(-"7/%",/")6*($"0&'<$%(*$)"$'"6'*(-)",&8D/%"."4$)";*')"4@/'/,?)$I"
18Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
e'C'_f
76#,3)0)#'Y']'"($'/'("0&37($"4$)";/0($6%)"4@$>0,6)*&'2"\p_"?$6>"&'("-(-"*'0,6)"4/')",@-(64$:"br"&'("-(-"(%/*(-)"/<$0",$"Y/'*+*h63/+"$("\l_"&'("-(-"(%/*(-)"/<$0",$"P$</0*h63/+I"E/"3&?$''$"4@L8$"-(/*("%$)7$0(*<$3$'("4$"nqIp"w"^"$("nqIl"w"^"/')"4/')",$)"8%&67$)"Y/'*+*h63/+"$("P$</0*h63/+I"E@FJ"$'",&8D/%"3&?$''$")@$)("/3-,*&%-$"4/')",$)"4$6>"8%&67$)"."\_"3&*)2"7/))/'("4$"rIqp"."rIbb"e7"x"rIrrqg"4/')",$"8%&67$"Y/'*+*h63/+"$("4$"rInr"."rIqn",&8D/%"e7"y"rIrbg"4/')",$" 8%&67$"P$</0*h63/+I" z" 6'" /'2" p_{"4$)" ?$6>" (%/*(-)" /<$0" ,$"Y/'*+*h63/+"&'("7$%46"3&*')"4$"rIc",&8D/%"4@FJ2"$'"0&37/%/*)&'"/<$0"^c{"4/')",$"8%&67$"P$</0*h63/+I" A$)" %-)6,(/()" )&'(" )*3*,/*%$)" ." 0$6>" &+)$%<$)" 4/')" ,$)" -(64$)" )6*</'($)G" DFYdfF" eplIq{g2" FfAMmY" epqIl{g" $(" =d]Y" eprI_{gI" E$" 8%&67$" Y/'*+*h63/+"/"%$V6"$'"3&?$''$"lIp_" *'U$0(*&')")6%"6'$"7-%*&4$"4$"\_"3&*)2"0&37/%/(*<$3$'(" ." lInb" *'U$0(*&')" 4/')" ,$" 8%&67$"P$</0*h63/+I"F7%`)" ,$)" c"*'U$0(*&')" 3$')6$,,$)" *'*(*/,$)2" _r{" 4$)" 7/(*$'()" 4/')" ,$" 8%&67$" Y/'*+*h6N3/+" $(" _q{" 4/')" ,$" 8%&67$" P$</0*h63/+" '@&'(" 7/)" $6" +$)&*'" 4@*'U$0(*&'" )677,-3$'(/*%$I"
Conclusion :"]'"0&37/%/*)&'"/<$0",$"(%/*($3$'("4$",/"CDEF"$>)64/(*<$"-(64*-"7/%" ,$)"4*<$%)$)"-(64$)"/3-%*0/*'$)2")&*("4$)" *'U$0(*&')" *'(%/<*(%-$''$)"3$'N)6$,,$)"7$'4/'("\_"&6"_l"3&*)2",/"7%-)$'($"-(64$"/"4-3&'(%-"56$"4$)"%-)6,(/()")*3*,/*%$)"$'"($%3$"4@/06*(-"<*)6$,,$"7$6<$'("9(%$"&+($'6)"/<$0"6'"'&3+%$"%-46*("4@*'U$0(*&')2"4*3*'6/'("/*')*",$)"0&|()"$(",$)"%*)56$)"/))&0*-)"/6>"*'U$0(*&')I"E$"Y/'*+*h63/+")$3+,$"(&6($;&*)"7,6)"$;;*0/0$"56$",$"P$</0*h63/+I"
Type de présentation :"R(64*/'($".",/"3/B(%*)$Nom du directeur de la recherche :"Cr"D/%0"M-+$%("
19Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
9 h 00
Décompression latérale et médiane pour la neuropathie optique compres-sive dans l’orbitopathie dysthyroïdienne
Catherine Baril1,22"T<&''$"D&,8/(\2_2c"$("C$'*)"=&6,*&(c2l
1"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I2"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI3"Mi7*(/,"4$",@]';/'(NX-)6)2"AMFI4"C-7/%($3$'("4@&(&%1*'&,/%?'8&,&8*$2"O/06,(-"4$"D-4$0*'$2"H'*<$%)*(-"E/</,I
Contexte et objectifs :"E@&%+*(&7/(1*$"4?)(1?%&}4*$''$"$)("6'$"3/,/4*$"*';,/3N3/(&*%$"/6(&*336'$"4&'(",$)"3-0/'*)3$)"71?)*&7/(1&,&8*56$)"*37,*56$'("6'$"/683$'(/(*&'"46"<&,63$"4$)" (*))6)"&%+*(/*%$)I"E$)"0&37,*0/(*&')"&06,/*%$)"4$"0$(($"7/(1&,&8*$"</%*$'("4$")?37(i3$)",-8$%)"U6)56@."4$)"0&'4*(*&')"3$'/V/'(",/"<*)*&'"($,,$",/"'$6%&7/(1*$"&7(*56$"0&37%$))*<$I"P*$'"56$",$)"0&%(*0&)(-%&}4$)"$(",/"%/4*&(1-%/7*$",&0/,$"76*))$'("9(%$"$37,&?-)"7&6%"3/B(%*)$%",/"'$6%&7/(1*$2",/"01*%6%8*$"4$"4-0&37%$))*&'"&%+*(/*%$"4$3$6%$"6'$"/,($%'/(*<$"7&6%"%$)(/6%$%",/"7&)*(*&'"'&%3/,$"46"8,&+$2")&6,/8$%",/"4&6,$6%"$("7$%3$((%$"6'$"3$*,,$6%$"7$%;6N)*&'"46"'$%;"&7(*56$I"A$(($"01*%6%8*$"'@$)("(&6($;&*)"7/)")/')"%*)56$I"E$"+6("4$",/"7%-)$'($"-(64$"$)("4@/'/,?)$%",$)"%-)6,(/()"0,*'*56$)"4$)"4-0&37%$))*&')",/(-N%/,$)"$("3-4*/'$)"7%/(*56-$)"7/%",$"C%"=&6,*&("emYEg"$(",/"C%$"D&,8/("e&71(/,3&N,&8*$g"4$76*)"\ppn"7&6%",/"'$6%&7/(1*$"&7(*56$"0&37%$))*<$"4/')",@&%+*(&7/(1*$"4?)(1?%&}4*$''$I"]'<*%&'"qr"7/(*$'()"&'("-(-"&7-%-)"$(",$)"%-)6,(/()"3-%*($%/*$'("4@9(%$"0&,,*8-)"$("7%-)$'(-)u76+,*-)I""
Méthodes :" E/"06$*,,$(($"4$)"4&''-$)")$" ;$%/" <*/"6'$" %$<6$" %-(%&)7$0(*<$"4$"4&))*$%)"4$)"7/(*$'()"/?/'(")6+*"6'$"01*%6%8*$"4$"4-0&37%$))*&'"&%+*(/*%$"$'"%/*)&'"4@6'$"'$6%&7/(1*$"&7(*56$"0&37%$))*<$"$'(%$",$"\$%"U/'<*$%"\ppn"$(",$"c\"4-0$3+%$"_r\rI
76#,3)0)#' 0))"&2,#' Y' E$)" 01$%01$6%)" $)7`%$'(" &+($'*%" 4$" ,@*';&%3/(*&'" )6%",@/3-,*&%/(*&'"4$" ,@/06*(-"<*)6$,,$"$'"7&)(N&7-%/(&*%$"$("7&))*+,$3$'("4@/6(%$)"7/%/3`(%$)"($,)",$)"/,(-%/(*&')"46"01/37"<*)6$,2",/"<*)*&'"4$)"0&6,$6%)2",$)"/'&N3/,*$)"767*,,/*%$)2"",/"7$%)*)(/'0$"&6",/"%-0*4*<$"4$",/"'$6%&7/(1*$2",$)"3$)6%$)"4$" ,@$>&71(/,3&3-(%*$" $(" 4$" ,/" ($')*&'" *'(%/&06,/*%$" $'" 7&)(N&7-%/(&*%$2" ,/"'-0$))*(-"4@/<&*%" %$0&6%)"."4@/6(%$)"3&4/,*(-)"4$"(%/*($3$'(" e0&%(*0&)(-%&}4$)2"%/4*&(1-%/7*$g2",@*'0*4$'0$"4$")(%/+&%$>*$"0&')-06(*<$".",/"01*%6%8*$"$(u&6",@*'0*N4$'0$"4$"7%&+,`3$)"4$)")*'6)"$'",*$'"/<$0"0$(($"01*%6%8*$I Type de présentation :"Y-)*4$'($"N"=%&+,-3/(*56$"4$"%$01$%01$Nom du directeur de la recherche :"Cre"T<&''$"D&,8/(
20Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
9 h 15
La suppression de l’expression du gène de la sous-unité !5 est intimement reliée aux propriétés tumorigènes de lignées cellulaires du mélanome uvéal
Marjorie Bergeron1,22"#&,/'8$"E/'4%$<*,,$32"O%/'V&*)"J*8'$/6,(42"#($$<$"E$0,$%0\2_2" D/'&'"Q/64%$/6,(\2_2"D&1*+"D&%0&)52" O%-4-%*0"D&6%*/6>\2_2"A1%*)(*/'"#/,$))$\2_ $("#?,</*'"Q6-%*'\2_ 1"Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI2"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I3"o/)1*'8(&'"H'*<$%)*(?"#01&&,"&;"D$4*0*'$2"C$7/%(3$'()"&;"m71(1/,3&,&8?"~"J*)6/," " #0*$'0$)2"H#FI4"M/%</%4"D$4*0/,"#01&&,2"Q$'$(*0)"C$7/%(3$'(2"P&)(&'2"H#FI5"C-7/%($3$'("4$"=/(1&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI
Introduction :"E$)"7%&7%*-(-)"*'</)*<$)"4$"(&6($"0$,,6,$"0/'0-%$6)$")&'("*'(*3$N3$'("%$,*-$)".")&'"1/+*,*(-".")$"4-7/%(*%"4$")&'"/'0%/8$".",/"3/(%*0$"$>(%/0$,,6,/*%$" eD]AgI"E@*'(-8%*'$"a!ba""\"0&'(%*+6$"."0$"7%&0$))6)"7/%")/",*/*)&'".")&'",*8/'4"4$",/"D]A2" ,/" ;*+%&'$0(*'$I"C/')"0$(($"-(64$2"'&6)"/<&')"0/%/0(-%*)-" ,@$>7%$))*&'"46"8`'$"4$",/")&6)N6'*(-"! ab"4/')"4$)",*8'-$)"0$,,6,/*%$)"46"3-,/'&3$"6<-/,"163/*'"/<$0"4$)"7%&7%*-(-)"(63&%*8`'$)"4*)(*'0($)"$("/<&')"4-($%3*'-"0$%(/*')"4$)"3-0/'*)3$)"56*" 7&6%%/*$'(" $>7,*56$%" ,$)" </%*/'0$)"4/')" ,$6%" /8%$))*<*(-I"DRSMmC]#" G" E@$>7%$))*&'" 4@a!b" /" -(-" -</,6-$" 4/')" ,$)" ,*8'-$)" 0$,,6,/*%$)" 46"3-,/'&3$"6<-/,"7/%"0?(&3-(%*$"4$";,6>I"E$)"7%&7%*-(-)"(63&%*8`'$)"4$)",*8'-$)"4$"3-,/'&3$"6<-/,"&'("-(-"-</,6-$)"7/%" ,$6%" *'U$0(*&'"4/')"4$)")&6%*)"/(1?N3*56$)I"E/",*/*)&'"4$)";/0($6%)"4$"(%/')0%*7(*&'"/6"7%&3&($6%"46"8`'$"a!b"/"-(-"-</,6-$2"*'"<*(%&2"7/%"%$(/%4)")6%"8$,"e]D#Fg"$("*'"<*<&"7/%"*336'&7%-0*7*(/(*&'"4$" ,/"01%&3/(*'$"eA1d=gI"E@$>7%$))*&'"4$)";/0($6%)"4$"(%/')0%*7(*&'"eOS)g"/"-(-"-</,6-$"7/%"+6</%4/8$)"o$)($%'"$(",$6%"*';,6$'0$"%-86,/(%*0$"7/%"(%/');$0(*&'"4$"7,/)3*4$)"%$0&3+*'/'()"7&%(/'("4*;;-%$'()")$83$'()"46"7%&3&($6%"ab";6)*&''-)"/6"8`'$"AFSI"f&6)"/<&')"-8/,$3$'("0%--"6'"</%*/'("4$",/",*8'-$"/8%$))*<$"Spn"e'-8/(*<$"7&6%" a!b" G"SpnNabNg"56*" )6%N$>7%*3$" ,/" )&6)N6'*(-" a!b" eSpnNab�g"$("/<&')"-(64*-")&'"7&($'(*$,"(63&%*8`'$"01$h",$)")&6%*)"/(1?3*56$)I"
76#,3)0)#'Y"H'$";&%($"$>7%$))*&'"4$",/")&6)N6'*(-" a!b"/"-(-"&+)$%<-$"4/')",$)",*8'-$)"4$"3-,/'&3$"6<-/,"'$"7%-)$'(/'("/606'"e&6"6'";/*+,$g"7&($'(*$,"(63&%*N8`'$"eS\r^"$("S\\bg"/,&%)"56$",@$>7%$))*&'"4@a!b"$)("*'4-($0(/+,$"e&6"(%`)";/*+,$g"4/')",$)",*8'-$)"/8%$))*<$)"eSpn"$("Sp^gI"E@$>7%$))*&'"$(",/",*/*)&'".",@FCf"4$)"OS)"#7\2"fOd"$("F=N\"/6"7%&3&($6%"ab"&'("-(-"4-3&'(%-$)"4/')"(&6($)",$)",*8'-$)"4$"3-,/'&3$"6<-/,I"S/'4*)"56$"F=N\"$("#7\"/0(*<$'(",@$>7%$))*&'"46"7%&3&($6%"a!b2"fOd")$3+,$"$>$%0$%"6'"76*))/'("$;;$("%-7%$))$6%")6%",/"(%/')0%*7(*&'"4$"0$"8`'$I"C$"7,6)2",/")6%$>7%$))*&'"4@a!b"4/')",/",*8'-$"Spn"7%&<&56$"6'$"/+&,*(*&'"0&37,`($"4$")&'"7&($'(*$,"(63&%*8`'$"01$h",$)")&6%*)"/(1?3*56$)I
21Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
9 h 15
Conclusion : f&)"%-)6,(/()")688`%$'("56$" ,@$>7%$))*&'"46"8`'$" ab"$)("4-7$'N4/'($"4@6'";%/8*,$"-56*,*+%$"4/')",$"%/(*&"4$)"OS)"56*"%-7%*3$'("efOdg"&6"/0(*<$'("e#7\"$("F=N\g",/"(%/')0%*7(*&'"4@ab"4/')",$)"0$,,6,$)"46"3-,/'&3$"6<-/,I"C$"7,6)2",@$>7%$))*&'"4$",/")&6)N6'*(-" ab"7&6%%/*("9(%$"%$)7&')/+,$"46"71-'&(?7$"3&*')"/8%$))*;"4$)",*8'-$)"0$,,6,/*%$)"46"3-,/'&3$"6<-/,I"A$)",*8'-$)"0$,,6,/*%$)"7&6%N%/*$'("%$7%-)$'($%"6'"7%-0*$6>"3&4`,$"/;*'"4@-(64*$%",/";&'0(*&'"4$",@*'(-8%*'$"aba\2"$("4$)"OS)"e($,)"56$"#7\2"#7c2"F=N\"$("fOdg"56*"$'"3&46,$'(",@$>7%$))*&'2"4/')",$"7%&0$))6)"4$"(%/');&%3/(*&'"4$)"3-,/'&0?($)"'&'N'-&7,/)*56$)"$'"3-,/'&3$"6<-/,"3-(/)(/(*56$I
Type de présentation :"R(64*/'($".",/"3/B(%*)$Nom du directeur de la recherche :"Cr"#?,</*'"Q6-%*'Nom du codirecteur :"Cr"A1%*)(*/'"#/,$))$"
22Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
9 h 30
Trabéculectomie et fermeture conjonctivale au limbe : résultats à long terme de la technique de Peng Khaw. Étude descriptive rétrospective. Pierre Lepage-Létourneau"$("P-/(%*0$"C$)"D/%01/*)"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMF"$("C-7/%($3$'("4@&71(/,3&N,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Contexte et objectifs : E/"(%/+-06,$0(&3*$"4$3$6%$"$'"_r\\",$"8&,4")(/'4/%4"$'"3/(*`%$"4$"(%/*($3$'("01*%6%8*0/,"4$"7%$3*`%$"*'($'(*&'"46"8,/60&3$I"d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�64)" $(" 7&6%%/*(" 7&($'(*$,,$3$'("4*3*'6$%" ,@*'0*4$'0$" 4$" 0&37,*0/(*&')" 7&)(N&7-%/(&*%$)I" A$(($" -(64$" /" 7&6%"+6("4@-</,6$%",$)"%-)6,(/()"4@6'$"'&6<$,,$"($01'*56$"4$";$%3$(6%$"0&'U&'0(*</,$" 7%/(*56-$"7/%"6'$"393$"01*%6%8*$''$2"'&(/33$'("$'" ($%3$)"4$" ;6*($)"7&)(N&7-%/(&*%$)"$("4$"($')*&'"*'(%/N&06,/*%$I"
Matériel et Méthodes :" f&6)" 7%&0-4$%&')" ." 6'$" -(64$" 4$)0%*7(*<$" 4$" (?7$" %-(%&)7$0(*<$" 3&'&0$'(%*56$I" E$)" 7/(*$'()" 7%&<*$'4%&'(" (&6)" 4$" ,/" +/)$" 4$" 4&''-$)"4$)"7/(*$'()"&7-%-)"." ,@1i7*(/,"46"#(N#/0%$3$'(I"E/"7&76,/(*&'"-(6N4*-$")$%/"0&37&)-$"4$"(&6)",$)"7/(*$'()"/?/'("$6"6'$"(%/+-06,$0(&3*$"/6"+,&0" &7-%/(&*%$"7/%",/"01*%6%8*$''$"C%$"P-/(%*0$"C$)"D/%01/*)"$'(%$",$"\er"U6*,,$("_rrp"$(",$"\er"/&|("_r\rI""
76#,3)0)#'0&)$($/6#'Y'f&6)"7%-<&?&')"56$",/"'&6<$,,$"($01'*56$"/6%/"7&6%"$;;$("4$"4*3*'6$%",$"'&3+%$"4$";6*($)"7&)(N&7-%/(&*%$)I Type de présentation :"Y-)*4$'($"N"=%&+,-3/(*56$"4$"%$01$%01$Nom du directeur de la recherche :"Cre"P-/(%*0$"C$)"D/%01/*)
23Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
g'C'_f
Fréquence d’apparition de la délétion commune de l’ADN mitochondrial dans les yeux humains.!680#)$"&'S"&21%&"$("=/(%*0W"XI"Y&01$(($Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMF"$("C-7/%($N3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Hypothèse :"A&33$",/"4-,-(*&'"0&336'$"4$",@FCf3("$)("0/(/,?)-$"7/%",$)"HJ2")&'"/77/%*(*&'"4/')",@�*,"163/*'"4$<%/*("0&%%-,$%"/<$0",/"7-'-(%/'0$"4$)"HJI"
Objectifs : E@&+U$0(*;" 8,&+/," 4$" 0$" 7%&U$(" $)(" 4@/'/,?)$%" ,$" %i,$" 4$)" HJ" 4/')" ,@/77/%*(*&'"4$",/"4-,-(*&'"0&336'$"4/')",@FCf3("4$)"0$,,6,$)"&06,/*%$)"$("4$"0&37%$'4%$" ,$)" 0&')-56$'0$)" 4$" ,@/00636,/(*&'" 4$" 0$(($" 4-,-(*&'" )6%" ,@�*," 163/*'I"C/')"0$(($"7/%(*$"4$"7%&U$(2"'&(%$"&+U$0(*;"<*)/*("."56/'(*;*$%",@/77/%*(*&'"4$",/"4-,-(*&'"0&336'$"$("4$",/"0&%%-,$%"/<$0",/"7-'-(%/'0$"4$)"HJ")&,/*%$)I"
Méthodes :"E/";%-56$'0$"4@/77/%*(*&'"4$",/"4-,-(*&'"0&336'$"4$",@FCf3("4/')",$)"4*;;-%$'($)")(%60(6%$)"&06,/*%$)"163/*'$)";6("/'/,?)-$"7/%"6'$"($01'*56$"4$"=AY"56/'(*(/(*;"$'"6(*,*)/'("4@6'$"7/*%$"4@/3&%0$)"0*+,/'("4$"7/%("$("4@/6(%$"4$",/"4-,-(*&'I"H'$"/6(%$"7/*%$"4@/3&%0$)"0*+,/'("6'$"%-8*&'"46"8-'&3$"3*(&01&'4%*/,"&�"/606'$"36(/(*&'"'@/"-(-"%$0$')-$"/")$%<*"4$"0&'(%i,$I"
76#,3)0)#' Y" f&6)" 4-3&'(%&')" 56$" ,/" 4-,-(*&'" 0&336'$" 4$" ,@FCf3(" 0&%%`,$"/<$0",/"7-'-(%/'0$"4$)"HJ"4/')",@�*,"/<$0"6'$"7%-4&3*'/'0$"4/')",/"0&%'-$I" =/%" 0&'(%$2" 0$" '@$)(" 7/)" ,@-7*(1-,*63"0&%'-$'"56*" 0&'(*$'(" ,$" 7,6)" 4$" 4-,-(*&'"0&336'$2"3/*)"+*$'",$")(%&3/"56*"$)("7&)(-%*$6%".",@-7*(1-,*63I"
Conclusion :" E$" ;/*(" 56$" ,/" 4-,-(*&'" 0&336'$" )$" %$(%&6<$" $'" ;&%($" 56/'(*(-"4/')" ,$")(%&3/"7,6(i("56$"4/')" ,@-7*(1-,*63"0&%'-$'")688`%$" ,@$>*)($'0$"4@6'" 3-0/'*)3$"4$"7%&($0(*&'"4$)"0$,,6,$)"4$",@-7*(1-,*63"0&%'-$'"0&'(%$",/"4-,-(*&'"0&336'$"4$",@FCf3(I
Type de présentation :"R(64*/'(".",/"3/B(%*)$Nom du directeur de la recherche :"Cr"=/(%*0W"XI"Y&01$(($
24Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
10 h 00
Mosaïcisme pigmentaire cutané et d’autres tissus: présentation oculaire atypique avec pressions intra-oculaires élevéesKarolina Chmielewska1,22"=/(%*0W"M/3$,3"$("C/'*$,,$"D/%0&6>4
1"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI"2"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I"3"#$%<*0$"4@&71(/,3&,&8*$2"C-7/%($3$'("4$"=-4*/(%*$2"AMH"4$"#/*'($NX6)(*'$2"O/06,(-"4$" " 3-4$0*'$2"H'*<$%)*(-"4$"D&'(%-/,I4"#$%<*0$"4$"C$%3/(&,&8*$2"C-7/%($3$'("4$"=-4*/(%*$2"AMH"4$"#/*'($NX6)(*'$2"O/06,(-"4$" " 3-4$0*'$2"H'*<$%)*(-"4$"D&'(%-/,I
Présentation du cas :"H'"+-+-"3/)06,*'"4$"c"3&*)"$("4$3*")@$)("7%-)$'(-".",/"0,*'*56$"4@&71(/,3&,&8*$"46"AMH"#($NX6)(*'$"7&6%"-</,6/(*&'I"z"0$"3&3$'(2"*,"-(/*(" 0&''6"7&6%" 4$" '&3+%$6)$)"3/,;&%3/(*&')" 4&'(" 6'" %$(/%4" )(/(6%&N7&'N4-%/,2" 6'$" 0%/'*&)?'&)(&)$2" 6'$" 1-3*1?7&7,/)*$" 4$" ,@1-3*0&%7)" 8/601$2" 6'$"1?7&(&'*$"/>*/,$"$("6'$"0,*'&4/0(?,*$I"F6"7%$3*$%"$>/3$'"&71(/,3&,&8*56$2",$)"7%$))*&')"*'(%/N&06,/*%$)"e7%*)$)"/6"S&'&7$'�g"-(/*$'("4$"cb"33M8"."4%&*($"$("cn"33M8"."8/601$I"m'"'&(/*("-8/,$3$'("6'$"8%*)/*,,$"0&%'-$''$2"6'$"3*0%&71N(/,3*$"4%&*($2"4$)" ,-)*&')"7L,$)"/6" ;&'4"4@�*,2" 6'$"1?7&7,/)*$"4$)"4$6>"'$%;)"&7(*56$)2"4$)"0/(/%/0($)"+*,/(-%/,$)"$("6'"'?)(/836)I"H'"$>/3$'")&6)"/'$)N(1-)*$"8-'-%/,$"/"7,6)"(/%4"4-3&'(%-"6'$"4?)8-'-)*$"46")$83$'("/'(-%*$6%"$("/"0&';*%3-",/"7%-)$'0$"4@1?7$%(&'*$"&06,/*%$"$("4$"7/7*,,$)"1?7&7,/)*56$)"/6";&'4"4@�*,I"E$)"+*,/')"8-'-(*56$)")$")&'("/<-%-)"'&%3/6>I"z"6'"/'"$("4$3*"4$"<*$2",$"7/(*$'(" /" 0&')6,(-" $'" 4$%3/(&,&8*$" &�" ,$" 4*/8'&)(*0" 0,*'*56$" 4@1?7&3-,/'&)$"4@d(&"/"-(-"7&%(-I"f$6;"3&*)"7,6)"(/%42",@$';/'("/"$6"6'$"7%$3*`%$"0&'<6,)*&'"$(")$")&'(")600-4-$)"4$)"%-0*4*<$)"-7*,$7(*56$)2"6'$"4$)"3/'*;$)(/(*&')"0,/))*56$)"4@1?7&3-,/'&)$"4@d(&I
Discussion :"m'"(%&6<$"7/%;&*)"4$)"3/,;&%3/(*&')")?)(-3*56$)"/))&0*-$)"."4$)"h&'$)" 4@1?7&7*83$'(/(*&'" )6*</'(" ,$)" ,*8'$)" 4$" P,/)01W&" e3&)/}0*)3$" 7*8N3$'(/*%$gI"A$(($"/))&0*/(*&'"$)(")&6<$'("'&33-$"1?7&3-,/'&)$"4@d(&"4/')" ,/",*((-%/(6%$" e0&'(%/*%$3$'(" ." ,/" 4$)0%*7(*&'" 4@d(&" &�" *," '@?" /</*(" 7/)" 4@/))&0*/N(*&'")?)(-3*56$�gI"E/"3/'*;$)(/(*&'"'$6%&,&8*56$",/"7,6)";%-56$'($"$)(",@-7*,$7N)*$2"7%-)$'($"4/')"br"."pr{"4$)"0/)I"E$)"/(($*'($)"36)06,&N)56$,$((*56$)",$)"7,6)" 0&6%/'($)" )&'(" ,@1-3*1?7$%(%&71*$" 46" 0&%7)" $(" ,$)" /'&3/,*$)" 4$)" 4&*8()"0&33$" ,/" 0,*'&4/0(?,*$I" X6)56@." _r{"4$)" 7/(*$'()" /6%&'(" 4$)"3/'*;$)(/(*&')"&71(/,3&,&8*56$)I"E$)"/'&3/,*$)",$)"7,6)")&6<$'("%$'0&'(%-$)"/6"'*<$/6"4$",@�*,")&'(",$)"h&'$)"4@1?7&7*83$'(/(*&'"/6";6'46)2",/"0/(/%/0($2",@1-(-%&01%&3*$"&6",$"4-0&,,$3$'("4$" ,/" %-(*'$I"E@/(%&71*$"&7(*56$2" ,@&7/0*;*0/(*&'"0&%'-$''$"$(" ,/"3*0%&71(/,3*$"($,,$)"56$"'&(-$)"01$h"'&(%$"7/(*$'(")&'("/6))*"4$)"3/'*;$)(/(*&')"4-0%*($)I"E@/'&3/,*$"4@F>$';$,4"e)/')"7%-)$'0$"4$"8,/60&3$g"/"-(-"4-0%*($"01$h"6'")$6,"7/(*$'("4/')",/",*((-%/(6%$I"
25Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
10 h 00
Conclusion :" E$" 3&)/}0*)3$" 7*83$'(/*%$" 06(/'-" 7$6(" 9(%$" /))&0*-$" ." 4$)"/(($*'($)")?)(-3*56$)"$(")$"3/'*;$)($"7/%;&*)"/6"'*<$/6"&06,/*%$I" d,"7$6("/,&%)"(&601$%"7%/(*56$3$'("(&6($)",$)")(%60(6%$)"4$",@&$*,I"f&(%$"7/(*$'("7%-)$'($"7,6N)*$6%)"4$)"3/'*;$)(/(*&')"0,*'*56$)"(?7*56$)"4$"0$(($"3/,/4*$2"(/'("/6"'*<$/6"4$",@�*,"56$"46")?)(`3$"4$%3/(&,&8*56$2"'$6%&,&8*56$"$("36)06,&N)56$,$((*56$I"z"'&(%$"0&''/*))/'0$2"*,")@/8*("46"7%$3*$%"0/)"&�"*,"?"/"4$"7,6)"7%-)$'0$"4$"8,/6N0&3$"&6"4@1?7$%(&'*$"&06,/*%$"7%*3/*%$"01$h"6'"7/(*$'("/(($*'("4$"3&)/}0*)3$"7*83$'(/*%$"$("4@/6(%$)"(*))6)2"/'0*$''$3$'("/77$,-"1?7&3-,/'&)$"4@d(&I
Type de présentation :"Y-)*4$'($"v"-(64$"4$"0/)Nom du directeur de la recherche :"Cr"=/(%*0W"M/3$,
26Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
10 h 35
Intérêt de la thermothérapie transpupillaire (TTT) isolée dans le traitement des naevi choroïdiens suspects Sébastien Turcotte1,22"C/'"P$%8$%&'\2_2"F,/*'"Y&6))$/6\2_2c"$("O%-4-%*0" D&6%*/6>\2_2c2l"
1"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI2"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"D-4$0*'$2"H'*<$%)*(-"E/</,I3"Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI4"C-7/%($3$'("4@&71(/,3&,&8*$2"A$'(%$"1&)7*(/,*$%"6'*<$%)*(/*%$"4$"A/$'2"O%/'0$I
Contexte et objectifs :"F67/%/</'(2",$)"'/$<*"4$"7$(*($"(/*,,$"-(/*$'(")6%<$*,,-)I"d,"?"/"\rN\b"/')"$)("/77/%6$",/"'&(*&'"4$";/0($6%)"4$"%*)56$"/))&0*-)"/6"'/$<6)I"F0(6$,,$3$'("4$)"0,*'*0*$')"7%&7&)$'("4$"(%/*($%",$)"'/$<*"/<$0";/0($6%)"4$"%*)56$"7/%",/"(1$%3&(1-%/7*$"(%/')767*,,/*%$"eSSSgI"E$"+6("$)("4$"j"+%|,$%"k",/"(63$6%"$("/*')*"4$"4-(%6*%$"6'"'/$<6)"7&6</'("-<&,6$%"<$%)"6'"3-,/'&3$I"E$)"0&37,*0/N(*&')"*'0,6$'(",/"7&))*+*,*(-"4$"%-0*4*<$"$(",$"%*)56$"4@/(($*'($"4$",@/06*(-"<*)6$,,$",&%)56$",/"(63$6%"$)(",&0/,*)-$"7%`)"4$",/";&<-/"&6"46"'$%;"&7(*56$I"C$)"-(64$)"&'("4-U."/'/,?)-",@*'(-%9("4$",/"(1$%3&(1-%/7*$"4/')",$"3-,/'&3$I"E$)"(/6>"4$"%-0*4*<$"-(/*$'("4$"^{"."bq{I"E$)"0%*(`%$)"4@*'0,6)*&'"$(",/"46%-$"4$")6*<*"-(/*$'("</%*/+,$)2"$>7,*56/'("0$(($"</%*/+*,*(-"46"(/6>"4$"%-0*4*<$)I"C$"7,6)2"0$)"-(64$)"*'0,6/*$'("4$)"7/(*$'()"/?/'("%$V6"6'"'&3+%$"</%*/+,$"4$"(%/*($3$'()"7/%"SSSI"]';*'2"$,,$)"'@/'/,?)/*$'("7/)",$)")&6)N8%&67$)"4$"7/(*$'()2"'&(/33$'(",$)"7/N(*$'()"/?/'("6'"'/$<6)")6)7$0("'&'"-<&,6(*;I"f&(%$"-(64$"<*)$"."4-0%*%$",$)"%-)6,N(/()"46"(%/*($3$'("7/%"SSS")6%",$)"'/$<*"01&%&}4*$')")6)7$0()"'&'"-<&,6(*;)I"F*')*2",$)"0&37,*0/(*&')2",$"4$<$'*%"<*)6$,2",$)"%-0*4*<$)"$(",@/77/%*(*&'"4$"3-(/)(/)$)")$%&'("-(64*-)I"C/')"6'"4$6>*`3$"($37)2"6'$"-(64$"0&37/%/(*<$")$%/"0&'46*($"$'"/'/,?)/'("/6))*",$)"7/(*$'()"/?/'("6'"'/$<6)")6)7$0("6'*56$3$'(")6%<$*,,-I" Matériel et méthodes :"f&(%$"-(64$"$)("6'$"%-(%&)7$0(*<$I"E$"8%&67$"j"(%/*(-"k"0&37&%($%/"(&6)",$)"7/(*$'()"(%/*(-)"7/%"c")-/'0$)"4$"SSS"4$"3/%)"_rr_".")$7N($3+%$"_r\\"7&6%"6'"'/$<6)")6)7$0(I"E$"8%&67$"j"0&'(%i,$"k"0&37&%($%/"(&6)",$)"7/(*$'()"/(($*'()"4@6'"'/$<6)")6)7$0("4$"U/'<*$%"\ppr"."U6*'"_rr^I"E$)"0&3N7,*0/(*&')2" ,$"4$<$'*%"<*)6$,2" ,$)" %-0*4*<$)"$(" ,@/77/%*(*&'"4$"3-(/)(/)$)")$%&'("-(64*-)I""
76#,3)0)#'0&)$($/6#'Y"f&6)"7%-<&?&')"6'"(/6>"4$"%-0*4*<$"/7%`)"SSS"7,6)";/*+,$"56$"0$6>"%$(%&6<-)"4/')",/",*((-%/(6%$"7&6%",$"(%/*($3$'("4@6'"3-,/'&3$"-<&,6(*;I"f&6)"7%-<&?&')"/6))*"6'" (/6>"4$" %-0*4*<$"/7%`)"SSS"7,6)" ;/*+,$"56$"01$h" ,$)"7/(*$'()"/?/'("+-'-;*0*-)"4@6'$")6%<$*,,/'0$I
Type de présentation :"Y-)*4$'("N"=%&+,-3/(*56$"4$"%$01$%01$Nom du directeur de la recherche :"Cr"O%-4-%*0"D&6%*/6>
27Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
10 h 50
Analyse des dommages induits par les rayons UVB à l’ADN des cellules du segment antérieur de l’œilJustin D. Mallet $("=/(%*0W"XI"Y&01$(($"Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMF"$("C-7/%($N3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Contexte et objectifs :" AmfS]tS]" ]S" mPX]ASdO#" G" E$" 0&%7)" 163/*'" $)("0&')(/33$'("$>7&)-"."4*<$%)"/8$'()"8-'&(&>*56$)"$'<*%&''$3$'(/6>"($,)" ,$)"%/?&')"6,(%/<*&,$()"46")&,$*," eHJgI"m'"7$')$")&6<$'(".",/"7$/6"0&33$"7%$3*$%"&%8/'$" /;;$0(-2" 0&')-56$33$'(" ,$)" $;;$()" 4$" %/?&')" HJ" )6%" 0$(" &%8/'$" )&'("3/*'($'/'("+*$'"4&063$'(-)I"P*$'"56$",$)"?$6>")&*$'("-8/,$3$'("4*%$0($3$'("$>7&)-)"/6>" %/?&')"46" )&,$*," $(" 56$"7,6)*$6%)"-<*4$'0$)" )688`%$'("6'$"0&%N%-,/(*&'"$'(%$",@$>7&)*(*&'")&,/*%$"$("7,6)*$6%)"7/(1&,&8*$)"&06,/*%$)"e$I8I"0/(/N%/0($)"0&%(*0/,$)2"0&'U&'0(*<*($)"/0(*'*56$)2"7(?8-%*63g2"7$6"4$"%$01$%01$)"&'("-(-"0&'46*($)"/;*'"4$"0&37%$'4%$",@$;;$("8-'&(&>*56$"4$)"HJ")6%",@�*,I"C/')"6'"&+U$0(*;"8,&+/,"4$"3*$6>"0&37%$'4%$",$)"$;;$()"4$)"HJ")6%",$)"?$6>2"0$"7%&U$("<*)$"."-</,6$%",/"7-'-(%/'0$"4$)"HJ"4/')",@�*,"$("."56/'(*;*$%",$)"4&33/8$)"*'46*()"7/%"0$)"%/?&')"4/')",$)"0$,,6,$)"4$)"4*;;-%$'($)")(%60(6%$)"&06,/*%$)I"
Matériel et méthodes :"E$)"?$6>"4$",/7*')"e/?/'("6'$"7%&7%*-(-"4$"7-'-(%/'0$"0&37/%/+,$"/6>"?$6>"163/*')g"&'("-(-"*%%/4*-)"/6>"%/?&')"HJP"$("4$)"0&67$)"4$)"4*;;-%$'($)")(%60(6%$)"&'("-(-"7%&46*($)I"E$)"4&33/8$)"*'46*()".",@FCf"&'("$')6*($"-(-"/'/,?)-)".",@/*4$"4@6'$"($01'*56$"4@*336'&1*)(&;,6&%$)0$'0$")6%",$)"4*;;-%$'($)"0&67$)"4$"(*))6)I"C$"0$(($";/V&'2"'&6)"/<&')"76"-(/+,*%",/"7-'-(%/'0$"4$)" HJ" $(" ,@-($'46$" 4$)" 4&33/8$)" 56@*,)" 0/6)$'(" /6>" 4*;;-%$'($)" )(%60(6%$)"&06,/*%$)I"
76#,3)0)#' Y"E$)"HJP" *'46*)$'("4$)"'*<$/6>"4-($0(/+,$)"4$"4&33/8$)"4*%$0()"/6")$83$'("/'(-%*$6%"4$",@�*,"e*I$I"0&%'-$2"*%*)"$("0%*)(/,,*'gI"E/"7%$3*`%$"0&601$"(&601-$2",@-7*(1-,*63"0&%'-$'2"$)(",/"7,6)"/;;$0(-$"7/%",@*%%/4*/(*&'I"=/%",/")6*($2",$"(/6>"4$"4&33/8$)"4*3*'6$"8%/46$,,$3$'("4/')",$)"0$,,6,$)"4$",/"0&%'-$"$("4$",@*%*)"U6)56@."4$<$'*%"*'4-($0(/+,$)"4/')",$)"0&601$)"7&)(-%*$6%$)"4$",@*%*)I"E$"0%*)(/,,*'"56/'(".",6*"7%-)$'($"4$)"4&33/8$)"6'*56$3$'("/6"'*<$/6"4$",/"767*,,$"4$",@�*,"e*I$I"'&'"7%&(-8-$"7/%",@*%*)gI"
28Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
10 h 50
Conclusions :"E$)")(%60(6%$)"&06,/*%$)"/'(-%*$6%$)"U&6$'("$;;*0/0$3$'(",$6%"%i,$"4$"+/%%*`%$"71?)*56$"." ,/"7-'-(%/'0$"4$)"HJP2"7%&(-8$/'("/*')*" ,$)")(%60(6%$)"7&)(-%*$6%$)"4$)"$;;$()"(&>*56$)"4$)"HJI"D/,8%-",@$'4&33/8$3$'("*37&%(/'("4$",@-7*(1-,*63"0&%'-$'2"/606'"0/'0$%"4$"0$(($")(%60(6%$"'@/"-(-"%$,*-".",@$>7&)*(*&'")&,/*%$I
Type de présentation :"R(64*/'(".",/"3/B(%*)$Nom du directeur de la recherche :"Cr"=/(%*0W"XI"Y&01$(($
29Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
11 h 05
D"%.$&EF'"#)B$3'0,)0&)'"5*(0("'+,"'3"':%)%@E'/%,1'3"')10$)"."&)'2,'836-pharospasme essentiel bénin?Julien Saad"$("F,/*'"Q&6%4$/6C-7/%($3$'(" 4@&71(/,3&,&8*$2" Mi7*(/," 4$" ,@]';/'(NX-)6)2" AMF:" A$'(%$" 6'*<$%)*(/*%$" 4@&71(/,N3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMF"$("C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"D-4$0*'$2" H'*<$%)*(-"E/</,I
Contexte et objectifs :"E$"+,-71/%&)7/)3$"$))$'(*$,"+-'*'"eP]Pg"$)("0/%/0(-%*)-"7/%"4$)"0&'(%/0(*&')"*'<&,&'(/*%$)"7%&8%$))*<$)"7-%*&%+*(/*%$)2"7&6</'("3$'$%"."6'$"&00,6)*&'"&06,/*%$"0&37,`($I"E$)"(%/*($3$'()"&'("0&33$"+6("4$"%-46*%$"&6"$)(&37$%",$)"0&'(%/0(*&')"*'<&,&'(/*%$)I""C$"(&6($)",$)"3&4/,*(-)"(1-%/7$6(*56$)"7&6%" ,$"P]P2" ,$)" *'U$0(*&')"4$"'$6%&(&>*'$"+&(6,*56$"4$3$6%$'(" ,/"7,6)"0&3N36'$I""E$"P&(&>�"eJ*)(/+$,�2"&'/+&(6,*'63(&>*'F:"F,,$%8/'"d'0g2",@/8$'(",$"7,6)"6(*,*)-"$'"F3-%*56$"46"f&%4"7&6%"(%/*($%"0$(($"3/,/4*$2"0&'(*$'("4$)"0&37,$>$)"7%&(-*'*56$)"/))&0*-)".",/"'$6%&(&>*'$I""A$)"0&37,$>$)"7%&(-*'*56$)"'@/;;$0($'("7/)",/"4*;;6)*&'"4$",/"'$6%&(&>*'$"$("'@/3-,*&%$'("7/)",/")(/+*,*(-"46"7%&46*("$'")(&0W/8$I""A$7$'4/'(2"56$,56$)"-(64$)"&'("4-3&'(%-",$"4-<$,&77$3$'("4@/'N(*0&%7)" '$6(%/,*)/'(" ,/" '$6%&(&>*'$" /<$0" 0$)" 0&37,$>$)" 7%&(-*'*56$)2" 0/6)/'("6'$"%-)*)(/'0$")$0&'4/*%$"/6"(%/*($3$'("7/%"*'U$0(*&'"46"P&(&>�I""E$"t$&3*'�" eP&0&6(6%$�2" *'0&+&(6,*'63(&>*'F:"D$%h" =1/%3/0$6(*0/,)" Q3+Mg" $)(" ,/" 7%$N3*`%$"7%-7/%/(*&'"4$"'$6%&(&>*'$")/')"0&37,$>$)"7%&(-*'*56$)2"56*"$)(")(/+,$".",/"($37-%/(6%$"/3+*/'($"7&6%"l"/')"$("56*"7&))`4$",$"393$"7%&;*,"4$"4*;;6N)*&'"56$",$)"7%-7/%/(*&')"/<$0",$)"0&37,$>$)"7%&(-*'*56$)I""f&(%$"7%&U$("<*)$"."0&37/%$%",@$;;*0/0*(-"46"t$&3*'�"."0$,,$"46"P&(&>�"4$";/V&'"4*%$0($2"01$h",$)"7/(*$'()")&6;;%/'("46"P]P"+*,/(-%/,"$(")?3-(%*56$I""
Matériel et méthodes :"E@$>7-%*3$'(/(*&'")$"4-%&6,$%/"." ,/"0,*'*56$"4$"'$6N%&N&71(/,3&,&8*$"4$" ,@Mi7*(/," 4$" ,@]';/'(NX-)6)I" " E$)"lb"7/(*$'()" )$%&'("4$)"7/(*$'()")6*<*)"7/%",$"C%I"Q&6%4$/6"7&6%"6'"P]P"+*,/(-%/,"$(")?3-(%*56$I""A1/06'"4$)"7/(*$'()"%$0$<%/"4$)"*'U$0(*&')"4$"P&(&>�"4@6'"0&(-"4$",$6%"<*)/8$"$("4$)"*'U$0(*&')"4$"t$&3*'�"4$",@/6(%$"0i(-"46"<*)/8$I""E$)"7/(*$'()")$%&'("%/'4&3*N)-)"7&6%"56$",/"3&*(*-"%$V&*<$",$"t$&3*'�")6%",$"0i(-"4%&*(2"$(",@/6(%$"3&*(*-")6%",$"0i(-"8/601$I""A$0*")$%/";/*("4$";/V&'"."4&6+,$"*')62"8%L0$".",@/*4$"4@6'"3$3+%$"46"7$%)&''$,"4$"%$01$%01$I""E$)"7/(*$'()")$%&'(")6*<*)"7&6%"56/(%$"(%/*($3$'()"0&')-06(*;)2"$(",$)")?37(i3$)")$%&'("-</,6-)"&+U$0(*<$3$'("7/%"C%I"Q&6%4$/62"/*')*"56$")6+U$0(*<$3$'("7/%",$)"7/(*$'()"."01/56$"<*)*($")$,&'",$"56$)(*&''/*%$")(/'4/%4*)-"4$"X/'W&<*0I
30Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
11 h 05
76#,3)0)#' 0&)$($/6#' Y" E$" %$0%6($3$'(" 4-+6($%/" $'" -(-" _r\\" $(" ,$)" 4&''-$)")$%&'(" 4*)7&'*+,$"7/%" 4-0$3+%$"_r\_I" "f&(%$"1?7&(1`)$"4$" (%/</*," $)(" 56$" ,$"t$&3*'�"$)("/6(/'("$;;*0/0$"56$",$"P&(&>�"7&6%",$"(%/*($3$'("46"P]PI
Type de présentation :"Y-)*4$'("v"7%&+,-3/(*56$"4$"%$01$%01$Nom du directeur de la recherche :"Cr"F,/*'"Q&6%4$/6
31Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
13 h 50
-01)%G10/C$"'2"#'GH&"#'.%2$*(0)",1#'2"'30'#6;61$)6'2,'G30,(%."'h'0&G3"'ouvertPascal Belleau12"#(-71/'$"C6+&*)12"Z/%*'$"E$+$,12"Y&)$"F%)$'$/6,(12"X$/'NE&6*)"F'0(*,_2c2"R%*0"#1*'W12"Q*,,$)"Ai($_2c2"D/%0$,"F3?&(42"Y-)$/6"Q,/60&3$"K6-+$0"$("J*'0$'("Y/?3&'4\2_
1 P*&,&8*$"4$)")?)(`3$)")$')&%*$,)2"AY]DmQ2"AYAMHE2"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"D-4$0*'$2"H'*<$%)*(-"E/</,I3"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI4"C-7/%($3$'("4@&71(/,3&,&8*$2"H'*<$%)*(-"4$"D&'(%-/,I
Contexte et objectifs : E$"8,/60&3$"7%*3/*%$"."/'8,$"&6<$%(" eQ=Fmg"$)("6'$"3/,/4*$"8-'-(*56$"0&37,$>$"0/6)-$"7/%"4$)"8`'$)"*'($%/8*))/'(")&6<$'("/<$0"4$)" ;/0($6%)" $'<*%&''$3$'(/6>I" ],,$" )$" 0/%/0(-%*)$" 7/%" 6'$" 4-8-'-%$)0$'0$" (?7*56$" 46" '$%;" &7(*56$I" =,6)" 4$" lb" 3*,,*&')" 4$" 7$%)&''$)" $'" )&6;;%$'(I" E/" 3/,/4*$" 7$6(" /6))*" )-8%-86$%" )$,&'" 6'"3&4$" /6(&)&3/," 4&3*'/'(I" =,6)*$6%)"8`'$)"/,(-%$'(",/")-<-%*(-"4$",/"36(/(*&'"7%*3/*%$"0/6)/,$I"A$)"8`'$)2"4*()"8`'$)"3&4*;*0/($6%)2" /00-,`%$'(" &6" %/,$'(*))$'(" ,/" 7%&8%$))*&'" 4$" ,/" 3/,/4*$I" f&6)"/<&')"%/77&%(-"56$",/"36(/(*&'"3?&0*,*'$2"DTmA"Zl_c]2"0/6)/*(",$"Q=Fm"4/')",/";/3*,,$"0/'/4*$''$N;%/'V/*)$"AFI"E$)"7&%($6%)"4$"0$(($"36(/(*&'"4-3&'(%/*$'("6'$"(%`)"8%/'4$"</%*/+*,*(-"4$",@L8$"/6"4*/8'&)(*0"eFFCgI"F7%`)"/<&*%"4-<$,&77-",/"3-(1&4$" 4$" j0,6)($%*'8" k"D]mf2" '&6)" /<&')" &+)$%<-" 56$" 0$(($" </%*/+*,*(-" 7&))-4/*("6'$"0&37&)/'($"8-'-(*56$I"E$"+6("4$"'&(%$"%$01$%01$"$)("4@*4$'(*;*$%",$"e&6",$)g"8`'$"3&4*;*0/($6%"56*"/00-,`%$"&6"%$(/%4$",@/77/%*(*&'"46"Q=FmI"
Matériel et méthodes :"=&6%",&0/,*)$%",$"8`'$"3&4*;*0/($6%2"'&6)"/<&')"%-/,*)-"6'" (&6%"4$"8-'&3$"$'"8-'&(?7/'("lrr"3/%56$6%)"3*0%&)/($,,*($)" %-7/%(*)")6%"(&6(",$"8-'&3$I"E$)"4&))*$%)"&71(/,3&,&8*56$)"4$"7,6)"4$"\nr"3$3+%$)"4$",/";/3*,,$"AF";6%$'(")0%6(-)"\I"/;*'"4$"4-($%3*'$%",$"4*/8'&)(*0"$(",/";*/+*,*(-"4$",@FFC"01$h",$)"3/,/4$)"$("_I"/;*'"4@?")-,$0(*&''$%"\^l"3$3+%$)I"=/%3*",$)\cc"1-(-%&Nh?8&($)"DTmA"Zl_c]")-,$0(*&''-)2"\rn")&6;;%/*$'("4@1?7$%($')*&'"*'(%/&06,/*%$"&6"4$"Q=Fm2"l"-(/*$'("1&3&h?8&($)"36(-)"/)?37(&3/(*56$)"$(" ,$)"ln"/6(%$)"-(/*$'("1&3&h?8&($)")/6</8$)"e*I$I"'$"7&%(/*$'("7/)",/"36(/(*&'gI"=&6%",&0/,*)$%",/"%-8*&'",*-$"."</%*/+*,*(-"4$",@L8$"/6"4*/8'&)(*02"n_"rrr"8-'&(?7$)";6%$'("-(6N4*-)"7/%"6'$"/'/,?)$"4$"(%/*("56/'(*(/(*;"&,*8&8-'*56$"4$",*/*)&'"$("4$")-8%-8/N(*&'"6(*,*)/'(",/"3-(1&4$"4$"D&'($NA/%,&"7/%"01/B'$)"4$"D/%W&<"*37,-3$'(-$"4/')"E&W*"A$(($"3-(1&4$"0/,06,$"6'"j"E")0&%$"k",$56$,"-</,6$",$"%/77&%("$'(%$",/"7%&+/+*,*(-"."7&)(-%*&%*"$(",/"7%&+/+*,*(-"/"7%*&%*"4@&+($'*%"6'$",*/*)&'I"E$")$6*,"4$")*8'*;*0/(*<*(-"01&*)*";6("4$"b{"7&6%"6'"j"E")0&%$"k"4$"nIcI"
32Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
13 h 50
76#,3)0)#'Y"H'",&06)"4$"\r"0D"/?/'("6'"j"E")0&%$"k")67-%*$6%"."̂ 2"4&'0")*8'*;*0/(*;2" ;6("0/%(&8%/71*-")6%",@6'$"4$)"__"7/*%$)"4@/6(&)&3$)I"E/"</,$6%"46"j"E")0&%$"k ;6("0/,06,-$"."nIl2"393$",&%)56$"'&6)"$>0,6*&')",$)"\\"*'4*<*46)"56*"7%-)$'(/*$'("4-U." 6'$" 4-8-'-%$)0$'0$" &7(*56$" /</'0-$" ,&%)" 46" 7%$3*$%" $>/3$'" &06,/*%$I" E@$37,/0$3$'("46",&06)")$%/"4-<&*,-"56/'4"'&6)"/6%&')"*4$'(*;*-",$"3&4*;*0/N($6%I"f&6)"/<&')"4$"7,6)2",&0/,*)-"c"/6(%$)",&0*"7&($'(*$,)"/?/'("4$)"</,$6%)"4$"j"E")0&%$"k"</%*/'("$'(%$"b"$("n"0$"56*")688`%$"6'$"+&''$"7%&+/+*,*(-"4$",*/*)&'"/<$0",@FFCI"
Conclusion :"f&6)"/<&')"0/%(&8%/71*-"6'$"%-8*&'"01%&3&)&3*56$",*-$"."6'"L8$"/6"4*/8'&)(*0"7,6)"U$6'$"7&6%",$"8,/60&3$I"E$",&06)"DmQ\"e3&4*;*0/($6%"8,/6N0&3$"\g"0&'(*$'("6'"8`'$"3&4*;*0/($6%"7&6%",/"3/,/4*$I"f&6)")&33$)"."0&';*'$%"0$",&06)"$("."0&';*%3$%",$)"c"/6(%$)",&0*I"E/"4-0&6<$%($"4$"8`'$"3&4*;*0/($6%"j"7%&($0($6%"k"7$%3$((%/"4$"4-<$,&77$%"4$"'&6<$,,$)";&%3$)"4$"(%/*($3$'("7&6%",/"0-0*(-I
Type de présentation :"R(64*/'("/6"4&0(&%/(Nom du directeur de la recherche :"Cr"J*'0$'("Y/?3&'4Nom du codirecteur :"Cr"R%*0"#1*'W
33Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'if
762,()$%&' 2"' 30' +,0&)$)6' 2"' (%1)$(%#)61%I2"' )%/$+,"' &6("##0$1"' 20&#' 3"' traitement de l’uvéite antérieure aiguë par l’adjonction d’un anti- $&K0..0)%$1"'&%&'#)61%I2$"&')%/$+,"`0361$"'S1%&2$&1,2 $("=*$%%$"C686/?\2_2c
1"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"#(N#/0%$3$'(2"AMFI2"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"D-4$0*'$2"H'*<$%)*(-"E/</,I3"C-7/%($3$'("4@&71(/,3&,&8*$2"Mi($,NC*$6"4$"E-<*)2"E-<*)I
Contexte et objectifs : E@6<-*($" /'(-%*$6%$" /*86�" $)(" 6'$" 0/6)$" 0&6%/'($" 4$"0&')6,(/(*&'"$'"&71(/,3&,&8*$I"E$" (%/*($3$'("/0(6$,"4$"0$(($"0&'4*(*&'" %$7&)$"3/U&%*(/*%$3$'(" )6%" ,@/77,*0/(*&'" (&7*56$" 4$" 0&%(*0&)(-%&}4$)I" d," )@/8*(" 4@6'" (%/*($3$'("$;;*0/0$2"3/*)"56*"'@$)("7/)"4-'6-"4@$;;$()")$0&'4/*%$)"'&0*;)"7&6%" ,/")/'(-"&06,/*%$I"E$)"0&%(*0&)(-%&}4$)"7$6<$'("7%-0*7*($%"4$)"7%&+,`3$)"($,)"56$",$"8,/60&3$"&6",/"0/(/%/0($I"=/%"/*,,$6%)2",$)"/'(*N*';,/33/(&*%$)"'&'N)(-%&}4*$')" (&7*56$)" )&'(" 0&6%/33$'(" 6(*,*)-)" 4/')" ,$" (%/*($3$'(" 4$" 0$%(/*'$)" /;;$0(*&')"*';,/33/(&*%$)"&06,/*%$)"$(",/"3&%+*4*(-"56*",$6%"$)("/))&0*-$"$)(";/*+,$I"E$"7%&NU$("4$"%$01$%01$"3*)"$'"+%/',$"/"7&6%"&+U$0(*;"4@-</,6$%",@$;;*0/0*(-"4@6'"/'(*N *';,/33/(&*%$"'&'")(-%&}4*$'"7&6%"%-46*%$",$"'&3+%$"(&(/,"4$"8&6(($)"4$"0&%(*N0&)(-%&}4$"'-0$))/*%$"4/')",$"(%/*($3$'("4@6'"-7*)&4$"/*86"4@6<-*($"/'(-%*$6%$I"
Méthode :" E$" %$0%6($3$'("7&6%" ,$" 7%&U$(" 4$" %$01$%01$" )$"4-%&6,$"7%-)$'($N3$'("/6"4-7/%($3$'("4@&71(/,3&,&8*$"46"A$'(%$"6'*<$%)*(/*%$"4$",@�*,2".",@1i7*(/,"#/*'(N#/0%$3$'("/*')*"56@.",@Mi($,NC*$6"4$"E-<*)I"f&)")6U$()"4@-(64$")&'("4$)"7/(*$'()" /46,($)" /?/'(" %$V6" 6'" 4*/8'&)(*0" 4$" 7%$3*$%" -7*)&4$" &6" 4$" %-0*4*<$"4@6<-*($" /'(-%*$6%$" /*86�I" f&6)" '@/<&')" 7&6%" ,$"3&3$'(" %-6))*" 56@." %$0%6($%"6'$"4*h/*'$"4$"7/(*$'()"(&6("/6"7,6)I"C/')",$"0/4%$"4$",@$))/*"0,*'*56$"%/'4&N3*)-"."4&6+,$" *')62" ,$)"7/(*$'()" )&'(" %-7/%(*)"$'"4$6>"8%&67$):" ,@6'" (%/*(-"4$"3/'*`%$"0&'<$'(*&''$,,$"/<$0"6'"0&%(*0&)(-%&}4$"(&7*56$"$("6'"7,/0$+&2"$(",@/6(%$"(%/*(-"/<$0"6'$"0&3+*'/*)&'"4@6'"0&%(*0&)(-%&}4$"$("4@6'"/'(*N*';,/33/(&*%$"'&'" )(-%&}4*$'"(&7*56$I
76#,3)0)#'")'0&03N#"#'Y"E@1?7&(1`)$"56$"'&6)"<&6,&')"0&';*%3$%"$)("56$",@/77,*N0/(*&'"4@6'"/'(*N*';,/33/(&*%$"'&'")(-%&}4*$'"(&7*56$"(%&*)";&*)"7/%"U&6%"4/')",@�*,"/(($*'("4@6<-*($"/'(-%*$6%$"/*86�"7&6%%/*("%-46*%$"4$"_b{",$"'&3+%$"4$"8&6(($)"4$"0&%(*0&)(-%&}4$"6(*,*)-$)"4/')" ,$"(%/*($3$'("4$"0$("-7*)&4$I"=&6%"4-3&'(%$%"0$(($" 1?7&(1`)$2" '&6)" 0&37(&')" /<&*%" %$0&6%)" /6" 0/,06," 4$" ,/" 4*;;-%$'0$" 4$"3&?$''$)"$'(%$",$)"4$6>"8%&67$)I"f&6)"7&6%%&')"-8/,$3$'("/'/,?)$%",@$;;$("4$",@/'(*N*';,/33/(&*%$"'&'N)(-%&}4*$'"$'";&'0(*&'"4$",/")-<-%*(-"4$",@*';,/33/(*&'" *'(%/&06,/*%$"($,,$"56$"4-($%3*'-$".",@$'(%-$"4/')",@-(64$I""""
34Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'if
Discussion :"f&6)"/<&')"-7%&6<-"+$/60&67"4$"4*;;*06,(-)"."%$0%6($%",$"'&3+%$"'-0$))/*%$"4$")6U$()".",@-(64$"$'"($37)"<&6,6I"f&6)"7$')&')"/<&*%"(%&6<-"0$%N(/*'$)"$>7,*0/(*&')"$("7*)($)"4$")&,6(*&'"."0$"7%&+,`3$I"f&6)"4$3$6%&')"0$7$'N4/'("0&'</*'06)"4$",/"7$%(*'$'0$"4$"7&6%)6*<%$"0$"7%&U$("4$"%$01$%01$I".
Type de présentation : Y-)*4$'($"N"=%&U$("($%3*'-Nom du directeur de la recherche :"Cr"=*$%%$"C686/?
35Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'[i
Faut-il continuer à demander un bilan hépatique pour détecter les métas-tases hépatiques dans le mélanome de la choroïde ? Frédéric MouriauxTF[FjF_2"A/%&,*'$"C&%*&52"C/'"P$%8$%&'c2l2"D/%(1$"D$%0*$%32"F,/*'"Y&6))$/6\2c2l 1"Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI2"C-7/%($3$'("4@&71(/,3&,&8*$2"A$'(%$"1&)7*(/,*$%"6'*<$%)*(/*%$"4$"A/$'2"O%/'0$I3"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI4"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I5"HY]=#2"A$'(%$"4$"%$01$%01$"OY#K"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI
Introduction :"E$)"-(64$)")&'("0&'(%/4*0(&*%$)"$'"0$"56*"0&'0$%'$",@*'(-%9("4$",/"+*&,&8*$"1-7/(*56$"4/')",$"4*/8'&)(*0"7%-0&0$"4$)"3-(/)(/)$)"1-7/(*56$)"4/')",$"3-,/'&3$" 4$" ,/" 01&%&}4$I" E$)" 0$'(%$)" f&%4"F3-%*0/*')" 6(*,*)$'(" ,/" +*&,&N8*$"1-7/(*56$"<&*%$",@-01&8%/71*$"1-7/(*56$"4/')",$")6*<*"4$)"3-,/'&3$)"4$",/"01&%&}4$I"F",@*'<$%)$2"$'"]6%&7$",$")6*<*"7/%"+*&,&8*$"1-7/(*56$"$)("%/%$"$("6'$")6%<$*,,/'0$"-01&8%/71*$"1-7/(*56$" (&6)" ,$)"q"3&*)"$)("7%&7&)-$2"'&(/33$'("$'"O%/'0$I"F6"0$'(%$"&'0&,&8*56$"&71(/,3&,&8*56$"4$",@1i7*(/,"#/*'("#/0%$3$'("4$"K6-+$02",$)"7/(*$'()"+-'-;*0*$'("4@6'$")6%<$*,,/'0$"+*&,&8*56$"1-7/(*56$"(&6)",$)"q"3&*)"$("4/')"0$%(/*')"0/)"4@6'$"-01&8%/71*$"1-7/(*56$"/''6$,,$"4/')",$")6*<*"4@6'"3-,/'&3$"4$",/"01&%&}4$"(%/*(-I"E&%)56$"56@6'$"/'&3/,*$")6%",$"+*,/'"+*&,&8*56$"1-7/(*56$"$)("&+)$%<-$2"6'"+*,/'"4@*3/8$%*$"1-7/(*56$"$)("7%&7&)-"/;*'"4@&+U$0(*<$%"&6"'&'",/"7%-)$'0$"4$"3-(/)(/)$)"1-7/(*56$)I"
Buts de l’étude :"\g"R(64*$%",/"+*&,&8*$"1-7/(*56$"$'"(/'("56$";/0($6%"7%&'&)(*0"4/')",$"4-7*)(/8$"7%-0&0$"4$)"3-(/)(/)$)"1-7/(*56$)I""_g"A%-/(*&'"4@6'"3&4`,$"4$"%-8%$))*&'"4$"A&>"-</,6/'(" ,@*37/0("4$"0$)"3/%56$6%)"1-7/(*56$)"/))&0*-"/6>";/0($6%)"1*)(&N7%&'&)(*56$)"4/')",@/77/%*(*&'"4$)"3-(/)(/)$)"1-7/(*56$)I"cg"R,/+&%$%"6'"3&4`,$"-0&'&3*56$"4$"(?7$"j"*37/0("+648-(/*%$"k"-</,6/'("$'"($%3$";*'/'0*$%",$)"0&|()"4$",@6(*,*)/(*&'"46"+*,/'"1-7/(*56$"4/')",$"4-7*)(/8$"7%-0&0$"4$)"3-(/)(/)$)
Matériels et méthodes : "F"7/%(*%"4$" ,/"+/'56$"4$"3-,/'&3$"4$" ,/"01&%&}4$"'&6)" *4$'(*;*$%&')" ,$)"7/(*$'()"/?/'("4-<$,&77-)"4$)"3-(/)(/)$)")$0&'4/*%$N3$'("$("/?/'("-(-")6*<*)"4$";/V&'"+*/''6$,,$"7/%"6'"+*,/'"+*&,&8*56$"1-7/(*56$"e,/)7/%(/($N/3*'&(%/');$%/)$"eF#Sg2"/,/'*'$N/3*'&(%/');$%/)$"eFESg2"8/33/N86(/3?,N(%/');$%/)$" eaQSg2" ,/0(&4$)1?4%&8/'/)$" eECMg2" 71&)71/(/)$" /,W/,*'$"e=FgI"f&6)"-(64*$%&')" ,/")$')*+*,*(-2" ,/")7-0*;*0*(-2" ,/"</,$6%"7%-4*0(*<$"7&)*(*<$2",/"</,$6%"7%-4*0(*<$"'-8/(*<$"$(",$"%/77&%("4$"<%/*)$3+,/'0$"4$)"0$)"3/%56$6%)"
36Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'[i
1-7/(*56$)I" " A$)" 4*;;-%$'()" 3/%56$6%)" 1-7/(*56$)" )$%&'(" -(64*-)" 4$" ;/V&'"*)&,-)" $(" 4$" ;/V&'" 0&3+*'-)I" E$"3&4`,$" 4$" %-8%$))*&'" ,&8*)(*56$" 7%$'4%/" $'"0&37($",@L8$2",$")$>$2",$"4*/3`(%$"$(",@-7/*))$6%"4$",/"(63$6%2",/"7*83$'(/(*&'2",/" ,&0/,*)/(*&'"$(",$)"4*;;-%$'()"3/%56$6%)"1-7/(*56$)"/'/,?)-)"4$";/V&'"*)&,-$"&6" 0&3+*'-)I" E$" 3&4`,$" -0&'&3*56$" 4@*37/0(" +648-(/*%$" 7%$'4%/" $'" 0&37($",$)";%/*)"4*%$0()"$(",$)";%/*)"*'4*%$0()",*-)"."/6>"$>/3$')"+*&,&8*56$)"e$>/3$')"4@*3/8$%*$2"+*&7)*$2" %-7$%06))*&'")6%" ,$)"$>/3$')"4@*3/8$%*$2"+*&7)*$2" %-7$%N06))*&'")6%",@/0(*<*(-"7%&;$))*&''$,,$g
37Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'jf
M./0()' 2"' 2$5561"&)#' )N/"#' 2"' )10$)"."&)' 0&)$B$&K0..0)%$1"' /%#)B)1086-(,3%/30#)$"'0,'30#"1'#63"()$5'#,1'30')"&#$%&'$&)10%(,30$1"'(C"9'3"#'/0)$"&)#'atteints de glaucome primaire à angle ouvertIsabelle Aucoin1,22"#&71*$"A1/37/8'$\2_2"m,*<*$%"E/)'*$%_2c2"X$/'NE&6*)"F'0(*,\2_2l2" F''*$" Q&?$(($\2_2" A/%&,*'$" E/U&*$\2_2" D/%*$NX&)-$" O%$4$(($\2_2l" $(" P-/(%*0$" C$)"D/%01/*)\2_2l
1"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI2"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I3"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"4$"#1$%+%&&W$I4"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"K6-+$0I
Contexte et objectifs : E/"(%/+-06,&7,/)(*$"7/%",/)$%")-,$0(*;"eSE#g"$)("4$<$'6$"6'" (%/*($3$'(" ,/)$%"4$"01&*>"7&6%" ,$" (%/*($3$'("46"8,/60&3$I"C/')" ,/"7-%*&4$"7&)(NSE#2",$"01&*>"4@6'$"3-4*0/(*&'"7,6(i("56@6'$"/6(%$"$)("7%-)$'($3$'(";&'4-")6%" ,$)" &7*'*&')" 4$)" &71(/,3&,&8*)($)" $;;$0(6/'(" ,$" (%/*($3$'(" 7,6(i(" 56$" )6%"4$)"-<*4$'0$)")0*$'(*;*56$)I"A$(($"-(64$"/"7&6%"+6("4$"4-($%3*'$%")@*,"?"/"6'$"4*;;-%$'0$")*8'*;*0/(*<$"$'(%$",@6'"&6",@/6(%$"4$)"(%/*($3$'()";%-56$33$'("6(*,*)-)"$'"7&)(NSE#2")&*(",@/0-(/($"4$"7%$4'*)&'$"\{"e6'"0&%(*0&)(-%&*4$g2",$"4*0,&;-'/0"rI\{"e6'"Fdf#g"&6"6'"7,/0-+&2"/;*'"4@&+($'*%"6'$"3$*,,$6%$"$;;*0/0*(-"4$",/"SE#"."3&?$'"($%3$"eq"3&*)gI"
Matériel et méthodes :"d,")@/8*("4@6'$"-(64$"7%&)7$0(*<$2"%/'4&3*)-$"."4&6+,$"*')62"/<$0"8%&67$"0&'(%i,$I"E/"4&''-$"7%*'0*7/,$"$)(",/"($')*&'"*'(%/&06,/*%$"."q"3&*)"7&)("SE#I"bc"?$6>"&'("7/%(*0*7-".",@-(64$".",@Mi7*(/,"#(N#/0%$3$'("4$"K6-N+$0"$'(%$"3/%)"_rr^"$(";-<%*$%"_rrpI"H'$"7%&0-46%$"&7-%/(&*%$")(/'4/%4"/"-(-"/77,*56-$".",@$')$3+,$"4$)"7/(*$'()"7/%(*0*7/'("."0$(($"-(64$I"E$)"7/(*$'()"&'("-(-"/,-/(&*%$3$'("4*)(%*+6-)"$'"(%&*)"8%&67$)"4*;;-%$'()"G",@/0-(/($"4$"7%$4'*)&'$"\{2",$"4*0,&;-'/0"rI\{"$("6'"7,/0-+&I"E$)"(%&*)"(%/*($3$'()"&'("-(-"/43*'*)(%-)"."%/*)&'"4$"56/(%$"8&6(($)"7/%"U&6%"e3/(*'2"3*4*2")&*%"$("/6"0&601$%g"7$'4/'("0*'5"U&6%)I"E$)"($')*&')"*'(%/&06,/*%$)"&'("-(-"7%*)$)"."7,6)*$6%)"3&3$'()"7%-N4-N;*'*)"/6"0&6%)"4$",/"7-%*&4$"4$")6*<*"4$"q"3&*)I"E$)"$;;$()")$0&'4/*%$)"4$)"(%&*)"3&4/,*(-)"4$"(%/*($3$'("7&)(NSE#"&'("/6))*"-(-"-</,6-)".",@/*4$"4@6'"56$)(*&'N'/*%$"$("4$",@$>/3$'"&06,/*%$I"
76#,3)0)#' Y" F606'$" 4*;;-%$'0$" )(/(*)(*56$3$'(" )*8'*;*0/(*<$" '@/" -(-" &+)$%<-$"$'(%$",/"Sdm"."q"3&*)"7&)("SE#"7&6%",$)"(%&*)"8%&67$)"e8%&67$")(-%&}4$"G"+/*))$"4$"Sdm"_2b"33M8:"8%&67$"Fdf#"G"+/*))$"4$"l2\"33M8:"8%&67$"7,/0$+&"G"+/*))$"4$"\2p"33M8:"7"x"r2qcgI"F606'$"4*;;-%$'0$")*8'*;*0/(*<$"'@/"-(-"&+)$%<-$"$'(%$",@*';,/33/(*&'"4$",/"01/3+%$"/'(-%*$6%$",&%)56$",@&'"0&37/%$",$"8%&67$"7,/0$+&"/6>"8%&67$)")(-%&}4$)"$("Fdf#"46"8%&67$"."\")$3/*'$"e7"x"r2l\g"&6"."\"3&*)"/7%`)"SE#"e7"x"r2c\gI"E$"8%&67$"7,/0$+&"'@/"7/)"4-0,/%-"7,6)"4$"4&6,$6%"56$",$)"8%&67$)")(-%&}4$)"$("Fdf#"e7"x"r2^_gI"
38Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'jf
Conclusion :"f&(%$"-(64$"0&';*%3$"56@*,"?"/"$6"6'$"+/*))$")(/(*)(*56$3$'(")*8'*N;*0/(*<$"4$",/"Sdm"7&)("SE#"4/')",$)"(%&*)"8%&67$)I"E$"01&*>"46"(%/*($3$'("7&)(N&7-%/(&*%$"'@/"7/)"$6"4@$;;$(")*8'*;*0/(*;")6%",$"7&6%0$'(/8$"4$"%-460(*&'"4$"Sdm"4/')",$)"4*;;-%$'()"8%&67$)I"E$)"8&6(($)"/'(*N*';,/33/(&*%$)"e)(-%&}4*$''$)"&6"'&'g")&'(")&6<$'("7%$)0%*($)"$'"7&)(NSE#"4/')",@$)7&*%"4$"%-46*%$",@*';,/33/(*&'"*'(%/&06,/*%$"$("4$")&6,/8$%",$"7/(*$'("4$",@*'0&';&%("7&)(N&7-%/(&*%$I"d,"$)("*'(-N%$))/'("4$"'&($%"56$"'&6)"'@/<&')"4-3&'(%-"/606'$"4*;;-%$'0$")(/(*)(*56$3$'(")*8'*;*0/(*<$"'*")6%",@*';,/33/(*&'"*'(%/&06,/*%$2"'*",$"'*<$/6"4$"4&6,$6%"%$))$'(*"7/%" ,$" 7/(*$'(" 4/')" ,/" 7%$3*`%$" )$3/*'$" 7&)(N&7-%/(&*%$I"S&6($;&*)2" ,/" 7$(*($"(/*,,$"4$",@-01/'(*,,&'"$(",$"3/'56$"4$"76*))/'0$")(/(*)(*56$"7$6("/<&*%",*3*(-",/"7&))*+*,*(-"4$"4-0$,$%"6'$"4*;;-%$'0$"$'(%$",$)"(%/*($3$'()I"E/"%-7,*0/(*&'"4$"0$(($"-(64$"/<$0"6'"-01/'(*,,&'"7,6)"*37&%(/'("$)("*'4*56-$"$("$)("$'"0&6%)I
Type de présentation :"Y-)*4$'($"N"=%&U$("($%3*'-Nom du directeur de la recherche :"Cre"P-/(%*0$"C$)"D/%01/*)Nom du codirecteur :"Cre"D/%*$NX&)-$"O%$4$(($
39Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'fi
O@$#)"B)B$3',&"'P'-03($,.B.N1$#)%N3'#Q$)(C'R'(C"9'30'S-?ABTU'AC$3$//"'-03;"9"$("A1%*)(*/'"#/,$))$Em]t" u" AHmv%$01$%01$2" A$'(%$" 4$" %$01$%01$" 46" AMF2" Mi7*(/," 46" #(N#/0%$3$'(2" AMF" $(" C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Introduction : E$)"'$6%&7%&(-*'$)")$')*+,$)"/6"0/,0*63"efA#g";&%3$'("6'$";/N3*,,$"4$"\l"7$(*($)"7%&(-*'$)"$>7%*3-$)"4/')",$")?)(`3$"'$%<$6>"0$'(%/,I"],,$)")&'(2"7&6%",/"7,67/%(2"/0?,-$)"/6"'*<$/6"fN($%3*'/,"7/%"6'"8%&67$3$'("3?%*)(&?,"4$"\l"0/%+&'$)I"E$)"fA#"7&))`4$'("-8/,$3$'("l"3&(*;)"]ONM/'4"7$%3$((/'(",/" ,*/*)&'"46" 0/,0*63I" E/" %$0&<$%*'$" /*')*" 56$" ,$)" 7%&(-*'$)" /0(*</(%*0$)" 4$" ,/"86/'?,/($" 0?0,/)$" eQAF=)g" %$7%-)$'($'(" ,$)" )$6,$)" fA#" $>7%*3-$)" /6" '*<$/6"4$)"71&(&%-0$7($6%)I"],,$)"3&46,$'(",/"0&'0$'(%/(*&'"46"QD=0"*'(%/0$,,6,/*%$2",$"7%*'0*7/,"3$))/8$%"4$",/"71&(&(%/')460(*&'I"E@/0(*<*(-"4$",/"%$0&<$%*'$"$)(" ,*-$".",@$>(%6)*&'"4$")&'"8%&67$3$'("3?%*)(&?,I"]'"$;;$(2"$'"/+)$'0$"4$"0/,0*632",/"%$0&<$%*'$"/4&7($"6'$")(%60(6%$"8,&+6,/*%$"4/')",/56$,,$"0$"3?%*)(&?,"$)("$';&6*"4/')",$"0�6%"4$",/"7%&(-*'$"$("3/*'($'6"4/')"6'$"7&01$"1?4%&71&+$I"E/",*/*)&'"46"0/,0*63"7/%",$)"3&(*;)"j"]ONM/'4"k"7$%3$(",/",*+-%/(*&'"4$"0$"8%&67$3$'("3?%*)(&?,I"A$"3-0/'*)3$"$)("/77$,-"0/,0*63"3?%*)(&?,")[*0(1I"d,"7$%3$(".",/"%$N0&<$%*'$"4$",*$%",$)"3$3+%/'$)"4$)"71&(&%-0$7($6%)"$("4$"0&37,$>$%",/"%1&4&7N)*'$"W*'/)$2")&'"$;;$0($6%I"=/%"0&'(%$2",@$>*)($'0$"4@6'$"($,,$"0/,0*63"3?%*)(&?,")[*0(1"7&6%",/"QAF=N\"$)("3&*')"0,/*%$"$(";/*("*0*",@&+U$("4@6'$"/'/,?)$"4-(/*,,-$"4$",@-(/("4$)"0&''/*))/'0$)I"
Analyse bibliographique :"R(/'("4&''-",$)"0/%/0(-%*)(*56$)")(%60(6%/,$)"0&3N36'$)"4$)"fA#2" *," /" ,&'8($37)"-(-"7%-)63-"56$" (&6($)"0$)"7%&(-*'$)"0&3N7&%(/*$'("6'$"j"0/,0*63"3?%*)(&?,")[*(01"kI"S&6($;&*)2")/"3*)$"$'"-<*4$'0$")@$)("%-<-,-$"0&37,*56-$I"]'"$;;$(2"7/%3*",$)"'&3+%$6)$)")(%60(6%$)"4$"fA#"0&''6$)"."1/6($"%-)&,6(*&'2")$6,$)",$)")(%60(6%$)"4$",/"QAF=N\"$("4$",/"%$0&<$%*'$"3?%*)N(&?,-$)"&'("-(-"4-($%3*'-$)"$'"7%-)$'0$"4$"0/,0*63I"A$)"4&''-$)"&'("3&'(%-",@$>(%6)*&'"46"3?%*)(&?,"4$",/"%$0&<$%*'$"/,&%)"56$",$"3?%*)(&?,"4$",/"QAF=N\"$)("%$)(-"$';&6*"4/')")/"7&01$"1?4%&71&+$I"A$7$'4/'(2"0$(($")(%60(6%$"4$",/"%$0&N<$%*'$"/"-(-"%-/,*)-$"/<$0"6'"\cN&>&N3?%*)(&?,I"d,"$)("7&))*+,$"56$",/"7%-)$'0$"4$"0$("&>?8`'$"4/')",/"01/B'$"0/%+&'-$"/*(";/<&%*)-",@$>(%6)*&'"4$"0$("/0*4$"8%/)"$'" 4*3*'6/'(" )&'" 1?4%&71&+*0*(-I" C$" 0$" ;/*(2" *," $)(" <%/*)$3+,/+,$3$'(" $%%&'-"4@6(*,*)$%"0$(($")(%60(6%$"7&6%"/;;*%3$%"56$",/"QAF=N\"'$"7&))`4$"7/)"4$"0/,0*63"3?%*)(&?," )[*(01I" =/%" /*,,$6%)2" 0$%(/*'$)" fA#" 7&6%" ,$)56$,,$)" ,@/+)$'0$" 4@6'$"0/,0*63"3?%*)(&?,")[*(01"/</*("-(-"3*)$"$'"-<*4$'0$2")&'("3/*'($'/'("*4$'(*;*-$)"0&33$"7&))-4/'("6'"3-0/'*)3$";&'0(*&''$,I"]'"$;;$(2",@6(*,*)/(*&'"4@/77%&01$)"+*&71?)*56$)" /" %-0$33$'(" 7$%3*)" 4$"3$((%$" $'" -<*4$'0$" 4$" ;/V&'" *'4*%$0($"6'$"0/,0*63"3?%*)(&?,")[*(01"01$h" ,/"QAF=N_2" ,/" ;%-56$'*'$2" ,/"'$6%&0/,0*'$2",@1*77&0/,0*'$"$(",/"JdEd=N\I
40Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
T_'C'fi
Objectifs :"E@$')$3+,$"4$)"(%/</6>"0&'0$%'/'(",@-(64$"4$"0$"3-0/'*)3$"01$h",$)"fA#" )688`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d," ;/64%/*("0&';*%3$%"0$)"4&''-$)"$'"4-($%3*'/'(",/")(%60(6%$"4$",/"QAF=N\"'&'"/0?,-$"$'"7%-)$'0$"$("$'"/+)$'0$"4$"0/,0*63"7/%"0%*)(/,,&8%/71*$I
Type de présentation :"R(64*/'("/6"4&0(&%/(Nom du directeur de la recherche :"Cr"A1%*)(*/'"#/,$))$
41Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
Tf'C'_f
Les facteurs de risque d’une fuite de bleb après une trabéculectomie : une étude descriptive rétrospective de type cas-témoins.Karolina Chmielewska $("P-/(%*0$"C$)"D/%01/*)A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMF"$("C-7/%($3$'("4@&71(/,3&N,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Contexte et objectifs : E/" ;6*($"4$"7,/*$")6*($"."6'$" (%/+-06,$0(&3*$"$)("6'$"0&37,*0/(*&'"8%/<$"7&6</'(")6%<$'*%"4/')",$)"U&6%)2",$)"3&*)2"<&*%$",$)"/''-$)")6*</'(" ,@*'($%<$'(*&'I"F<$0" ,@6(*,*)/(*&'" 0&6%/'($" 4$)" /8$'()" /'(*N3-(/+&,*($)"7&6%"/683$'($%",/")6%<*$"4$)"(%/+-06,$0(&3*$)2"&'"'&($"/6))*"6'$"/683$'(/(*&'"4$",/";%/8*,*(-"4$)"(*))6)"$(2"0&')-56$33$'(2"4$)";6*($)I"E$)"&+U$0(*;)"4$",@-(64$"-(/*$'("4$"0&37/%$%",$)"7/(*$'()"/?/'("$6"6'$";6*($")-<`%$"4$",$6%"+,$+"."6'$"7&76,/(*&'"&7-%-$"(-3&*'2"/;*'"4$"3$((%$"$'"-<*4$'0$"0$%(/*')";/0($6%)"4$"%*)56$"4$";6*($I"d,")@/8*("4@6'$"-(64$"%-(%&)7$0(*<$"4$"(?7$"0/)N(-3&*')I"
Matériel et méthodes : f&6)"/<&')"-(64*-"(&6)",$)"7/(*$'()"/?/'("$6"6'$"%-<*N)*&'"01*%6%8*0/,$"/6"+,&0"&7-%/(&*%$"$'(%$" ,$"\$%" U/'<*$%"$(" ,$"cr" U6*'"_rr^" e$("7%-)$'(/'("7/%",$";/*("393$"6'$";6*($")-<`%$gI"A1/56$"0/)"/"-(-"/77/%*-"."(%&*)"(-3&*')"$(",@/77/%*$3$'("/"-(-"7%/(*56-"7&6%",/"4/($"4$"01*%6%8*$"*'*(*/,$"46"0/)"e7,6)"&6"3&*')"_"3&*)gI"f&6)"/<&')"$')6*($"/'/,?)-"4*;;-%$'()";/0($6%)"%$,*-)"/6"7/(*$'(2".",@*'($%<$'(*&'2"&6"$'0&%$"/6")6*<*"$("3/'*76,/(*&')"7&)(N&7-%/(&*%$)I"YR#HESFS#"G"E@L8$"3&*')"/</'0-"$)("6'";/0($6%"4$"%*)56$"4$";6*($")-<`%$")(/(*)N(*56$3$'(")*8'*;*0/(*;"e7xrIrrq\g"4/')"'&(%$"-(64$I"]'";/*(2",$)"8$')"4$"3&*')"4$"bb"/')"&'("6'"%*)56$"+$/60&67"7,6)"8%/'4"56$",$)"7,6)"4$"nb"/')"4$"4-<$,&77$%"6'$";6*($"emYx_\g2"$("0$"%*)56$"4*3*'6$"4$";/V&'",*'-/*%$"$'")6*</'(",@L8$"01$h",$)"bbNnl"/')"e7xrIrr_pgI"E$"8,/60&3$"U6<-'*,$2"56*"/6%/*("76"9(%$"6'";/0($6%"0&';&'4/'(2"'@/683$'($"7/)",$"%*)56$"4$";6*($I"E/"46%-$"4@/77,*0/(*&'"4$"3*(&N3?0*'"A"e,@/8$'("/'(*N3-(/+&,*($"6(*,*)-"4/')"'&(%$"3*,*$6"$'"7$%"&7-%/(&*%$g"'@/"7/)"4-3&'(%-"6'$"/683$'(/(*&'"46"%*)56$I"E$"(?7$"4$"01*%6%8*$2",$"'&3+%$"4$"01*%6%8*$)"/'(-%*$6%$)2",$"'&3+%$"4$"3-4*0/(*&')"(&7*56$)"/'(-%*$6%$)2",/",&0/,*N)/(*&'"4$",/"7,/*$"01*%6%8*0/,$"'@&'("76"4-3&'(%-"4$"4*;;-%$'0$")*8'*;*0/(*<$"$'(%$"'&)"_"8%&67$)"-(64*-)I"
Conclusions :"E@L8$"3&*')"/</'0-",&%)"4@6'$"(%/+-06,$0(&3*$2"7/%(*06,*`%$3$'(",@L8$"*';-%*$6%"."bb"/')2"$)("6'";/0($6%"4$"%*)56$"7&6%",$"4-<$,&77$3$'("4@6'$";6*($")-<`%$"01$h",$)"7/(*$'()")6+*))/'(",@*'($%<$'(*&'I"A$)"7/(*$'()"4$<%/*$'("9(%$")6*<*)"4$"7,6)"7%`)")6*($".",/"01*%6%8*$I"
Type de présentation : Y-)*4$'($"v"7%&U$("($%3*'-Nom du directeur de la recherche :"Cre"P-/(%*0$"C$)"D/%01/*)
42Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
16 h 00
L’utilisation de lentilles intraoculaires (LIO) pliables suturées à la sclère en (0#'2408#"&("'2"'#,//%1)'(0/#,30$1"'")'9%&,30$1"'026+,0)Z'/C0#"'[Maxime Laroche1,22"D/%*$"]<$"E-8/%-\2_"$("Y$'-"C*'1\2_2c
1"A$'(%$"6'*<$%)*(/*%$"4@&71(/,3&,&8*$2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI2"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"D-4$0*'$2"H'*<$%)*(-"E/</,I3"C-7/%($3$'("4@&71(/,3&,&8*$2"AMHE2"A$'(%$"1&)7*(/,*$%"H'*<$%)*(/*%$"4$"K6-+$0"eAMHKgI
Contexte et objectifs : D/,8%-",$";/*("56@*,"?"/*("7,6)*$6%)"/77%&01$)"01*%6%8*0/,$)"7&6%")6(6%$%"6'$",$'(*,,$"*'(%/N&06,/*%$".",/")0,`%$2"*,"'@?"/"7/)"4$"0&')$')6)")6%",/"($01'*56$"&7(*3/,$I"C/')"0$(($"-(64$2"'&6)"-</,6&')",/")-06%*(-"$(",@$;;*0/0*(-"4$)" ,$'(*,,$)"7,*/+,$)";*>-$)"." ,/")0,`%$"6(*,*)/'("6'$"($01'*56$"/+" *'($%'&"/<$0"3*0%&N*'0*)*&')"$'"0&%'-$"0,/*%$"$("4$)")6(6%$)"4$"7&,?7%&7?,`'$"pIr"4&6+,$N3$'("3&'(-$)I"
Matériel et méthodes :" R(64$" %-(%&)7$0(*<$" 4$)" 7/(*$'()" 46"C%"C*'1" 56*" &'(")6+*"6'$"*37,/'(/(*&'"4$",$'(*,,$"*'(%/N&06,/*%$"7,*/+,$";*>-$".",/")0,`%$"4$";/V&'"7%*3/*%$"&6")$0&'4/*%$"7&6%"/71/W*$2")6+,6>/(*&'"46"0%*)(/,,*'2"-01/'8$"4$",$'N(*,,$" &6" /7%`)"6'" (%/63/"&06,/*%$" $'(%$" /<%*," _rrl"$(" U/'<*$%" _rrpI"A$'(" 0*'N56/'($N4$6>"7/(*$'()"&'("-(-"*4$'(*;*-)I"#&*>/'($N4&6h$"7/(*$'()"7&6%"6'"(&(/,"4$")&*>/'($N)$*h$"?$6>"-(/*$'("/43*))*+,$)"7&6%",$)"0%*(`%$)"4@*'0,6)*&'")6*</'()"G"H(*,*)/(*&'"4@6'$",$'(*,,$"7,*/+,$"DFbrPD"/<$0",$)"4$6>"1/7(*56$)")6(6%-$)".",/")0,`%$"/<$0"46"7&,?7%&7?,`'$"pIr"$("6'")6*<*"3*'*363"4$"4$6>"3&*)I"E@/06*(-"<*)6$,,$"0&%%$)7&'4".",/"3$*,,$6%$"/06*(-"<*)6$,,$"0&%%*8-$"ePAJFg"4/')",$"4&))*$%"/<$0",/"'&(/(*&'"4$")'$,,$'I"f&6)"/<&')"6(*,*)-",$"($)("4$")(64$'("7&6%",@/'/,?)$")(/(*)(*56$"$'(%$",@/06*(-"<*)6$,,$"7%-"$("7&)(&7-%/(&*%$I"S&6($)",$)"0&37,*0/(*&')"&'("-(-"%$,$<-$)"/6"0&6%)"4$",/"7-%*&4$"4$")6*<*I"
76#,3)0)#' Y"H'" (&(/,"4$"nq"?$6>"&'("-(-" *4$'(*;*-)"/<$0"6'")6*<*"3&?$'"4$"\b"3&*)" e_" ."b_"3&*)gI" ]'"7&)(&7-%/(&*%$2" ^\Iq"{"4$)"7/(*$'()" &'("3/*'($'6"&6"/3-,*&%-" ,$6%"/06*(-"<*)6$,,$"4$" ;/V&'")(/(*)(*56$3$'(")*8'*;*0/(*<$"7/))/'("4$"rIpb"E&8DFY"equqrg"."rIbc"equ\pgI"C$)"0&37,*0/(*&')")$")&'("7%&46*($)"4/')"cc"?$6>"elcIl"{gI"E/"3/U&%*(-"4@$'(%$"$,,$)"-(/*$'("(%/')*(&*%$)I"F606'$"1-3&%%/N8*$")67%/N01&%&}4*$''$"&6"4@$'4&71(/,3*$"'$")@$)("7%&46*($I" E/"0&37,*0/(*&'",/"7,6)" ;%-56$'($"/"-(-" ,@1?7$%(&'*$"&06,/*%$" (%/')*(&*%$I"S%&*)"?$6>" ec2p"{g"&'("7%-)$'(-"6'$")6(6%$"4$"7%&,`'$"$>7&)-$"."\"3&*)2"p"3&*)"$("cl"3&*)"%$)7$0N(*<$3$'("46%/'(",$")6*<*I"S%&*)"?$6>"ecIp{g"&'("7%-)$'(-"6'"7%&+,`3$"4$",$'(*,,$"*'0,*'-$"&6"4-0$'(%-$I"
43Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
16 h 00
Conclusion :"E@6(*,*)/(*&'"4$",/"($01'*56$"/+"*'($%'&"/<$0",$'(*,,$"*'(%/N&06,/*%$" 7,*/+,$" )6(6%-$" ." ,/" )0,`%$" 4/')" 0$(($" -(64$" )@$)(" /<-%-$" $;;*0/0$" $'" %$8/%4"4$" ,@/3-,*&%/(*&'" 4$" ,@/06*(-" <*)6$,,$" $(" )-06%*(/*%$" /<$0" %$,/(*<$3$'(" 7$6" 4$" 0&37,*0/(*&')")-%*$6)$)I"E@6(*,*)/(*&'"4$",/",$'(*,,$"7,*/+,$"$)("3&*')"*'</)*<$"$("7$%3$(" 6'$"86-%*)&'" 7,6)" %/7*4$I" E@/77%&01$" /+" *'($%'&" /77&%($" 6'$" )(/+*,*(-"*'(-%$))/'($"46%/'(",/"7%&0-46%$2"0$"56*"7$6("9(%$"6(*,$"4/')"0$%(/*'$)")*(6/(*&')"7/%(*06,*`%$)I
Type de présentation : Y-)*4$'("N"=%&U$("($%3*'-Nom du directeur de la recherche :"Cr"Y$'-"C*'1
44Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
?5*(C"'T
O@/1"##$%&F'/,1$*(0)$%&'")'3$0$#%&'.".810&0$1"'2"#'16)$&%3#'26#CN21%B génases 8 et 11Élodie Boisselier2"D/%*$NE&6"F64$(2"D/%*&"D-(1&(2"E*'$"A/'(*'"$(" A1%*)(*/'"#/,$))$
Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMF"$(" C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Contexte et objectifs : E@/+)&%7(*&'"4$",/",63*`%$"7/%",$"7*83$'("<*)6$,2",/"%1&N4&7)*'$2"3`'$".",@*)&3-%*)/(*&'"46"\\N0*)"%-(*'/,"$'"(&6(N(%/')"%-(*'/,"$(".")/"%-460(*&'"$'" (&6(N(%/')" %-(*'&,I"A$"4$%'*$%" 0&37&)-"$)("$')6*($" *)&3-%*)-"$'"\\N0*)"%-(*'&,"76*)"&>?4-"$'"\\N0*)"%-(*'/,"/;*'"4$"%-8-'-%$%",/"%1&4&7)*'$I"E$)"%-(*'&,)"4-)1?4%&8-'/)$)"eYCMg"56*")&'("(%`)"7$6"0/%/0(-%*)-$)"$;;$0(6$'("0$(($"*'($%0&'<$%)*&'"$'(%$" ,$)" ;&%3$)" %-(*'/," $(" %-(*'&,I"m'")/*(" 0$7$'4/'("56$"4$)"36(/(*&')"4$",/"YCMb"$("4$",/"YCM\_")&'("%$)7&')/+,$)"4$"4?)(%&71*$)"4$",/"%-(*'$I"E@&+U$0(*;"4$"0$)"(%/</6>"0&')*)($".")6%$>7%*3$%2"76%*;*$%2"3$)6%$%",@*'($N%/0(*&'"3$3+%/'/*%$"$("."4-($%3*'$%",/")(%60(6%$"4$",/"YCM^"$("4$",/"YCM\\I
Méthodes :"E/"YCM\\"0&'(*$'("6'"7$7(*4$"(%/')3$3+%/'/*%$"$'"fN($%3*'/,I"A$"7$7(*4$"4$"_q"/0*4$)"/3*'-)"/"-(-"&+($'6"0&33$%0*/,$3$'(I"E/"YCM\\"/*')*"56$",/"fN4$,"YCM\\"e6'"4-,-(/'("4$)"_q"7%$3*$%)"/0*4$)"/3*'-)"$'"fN($%3*'/,g"&'("-(-"0,&'-)2")6%$>7%*3-)"01$h"]I0&,*2"76%*;*-)"7/%"01%&3/(&8%/71*$"4@/;;*'*(-2"76*)"0&'0$'(%-)"7/%"6,(%/;*,(%/(*&'I"E@/0(*<*(-"4$",/"fN4$,"YCM\\"/"-(-"3$)6%-$"$'"7%-)$'0$"4$")&'")6+)(%/(2",$"(&6(N(%/')"%-(*'/,:",/"%-/0(*&'";6("*'*(*-$"7/%",@/U&6("4$" )&'"0&;/0($6%2" ,$"fFC=MI" E$)"7%&46*()" 4$" ,/" %-/0(*&'"&'(" -(-" /'/,?)-)"7/%"M=EAI"C$)"3$)6%$)"4$" ,*/*)&'"3$3+%/'/*%$"&'("-(-"$;;$0(6-$)"$'" *'U$0(/'(" ,/"YCM\\2",/"fN4$,"YCM\\"&6",$"7$7(*4$"$'"fN($%3*'/,"4/')",/")&6)N71/)$"4@6'$"3&'&0&601$"4$"71&)71&,*7*4$)".",@*'($%;/0$"/*%N$/6I"E$6%")(%60(6%$")$0&'4/*%$"$(",$6%"&%*$'(/(*&'"&'("-(-"4-($%3*'-$)"7/%")7$0(%&)0&7*$"*';%/%&68$I"E/"YCM^"/"-(-"0,&'-$"4/')"7,6)*$6%)"<$0($6%)"4@$>7%$))*&'"+/0(-%*$')")&*("$'";6)*&'"/<$0",/" 8,6(/(1*&'N#N(%/');-%/)$" eQ#Sg" &6" /<$0" ,/" 7%&(-*'$" 4$" ,*/*)&'" 46"3/,(&)$"eDP=g2")&*(")6%$>7%*3-$"/<$0"6'$"56$6$"7&,?N1*)(*4*'$"e7&,?NM*)g"/;*'"4@*4$'N(*;*$%",$)"0&'4*(*&')"&7(*3/,$)"4$"76%*;*0/(*&'I"C*;;-%$'()"($)()"4$"76%*;*0/(*&'"&'("-(-"$;;$0(6-)"$'"7%-)$'0$"4$"4*<$%)"4-($%8$'()"7&6%"/3-,*&%$%" ,/")&,6+*,*(-"4$" ,/"7%&(-*'$I
45Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
?5*(C"'T
76#,3)0)#'")'(%&(3,#$%&'Y'E$)"%-)6,(/()"&+($'6)"$'"M=EA"4-3&'(%$'("6'$"/0(*<*(-" (%`)"-,$<-$"4$",/"fN4$,"YCMN\\I"E/"0*'-(*56$"4$",*/*)&'"3$3+%/'/*%$"$'"3&'&N0&601$"</%*$"0&33$")6*(" G"7$7(*4$"$'"fN($%3*'/,"y"YCM\\"y"fN4$,"YCM\\2"0$"56*"$)("0&1-%$'("/<$0",$6%")(%60(6%$I"C$"7,6)2",$)"3$)6%$)"4$")7$0(%&)0&7*$"*';%/%&68$"&'("7$%3*)"4$"0&';*%3$%" ,/")(%60(6%$"$'"1-,*0$"/,71/"46"7$7(*4$"$'"fN($%3*'/,"$("4$"4-($%3*'$%")&'"&%*$'(/(*&'2"/*')*"56$"4$"0&37/%$%",/")(%60(6%$"$(",@&%*$'(/(*&'"4$",/"YCM\\"$("4$",/"fN4$,"YCM\\I"=&6%",/"YCM^2",$)"%-)6,(/()"&+($'6)"/<$0"0$)"3-(1&4$)")$%&'("-8/,$3$'("7%-)$'(-)IS?7$"4$"7%-)$'(/(*&'"G"#(/8*/*%$"7&)(N4&0(&%/,$
Nom du directeur de la recherche : Cr"A1%*)(*/'"#/,$))$
46Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
?5*(C"'[
76G,30)$%&'2"'340()$;$)6'2,'/1%.%)",1'2,'GH&"'!5 de l’intégrine !5 "1 par le collagène dans les cellules épithéliales de la cornéeJennifer Lake12"#($$<$"E$0,$%012"=/(%*0W"A/%%*$%12"E60*$"Q$%3/*'\2_2c2l2" A1%*)(*/'"#/,$))$\2l"$("#?,</*'"Q6-%*'\2l
1"Em]tuAHm"%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI2"E/+&%/(&*%$"4@&%8/'&8$'`)$"$>7-%*3$'(/,$"eEm]tg2"A$'(%$"4$"%$01$%01$"46"AMFI3"C-7/%($3$'("4$"01*%6%8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I4"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Contexte et objectifs : E/";*+%&'$0(*'$" eOfg2" ,*8/'4"4$" ,@*'(-8%*'$" a!ba""\2" U&6$ 6'" %i,$"3/U$6%" 4/')" ,/" 0*0/(%*)/(*&'" 0&%'-$''$" $'" ;/<&%*)/'(" ,@/41-)*&'" $(" ,/"3*8%/(*&'"4$)"0$,,6,$)"-7*(1-,*/,$)")6%",/"3/(%*0$"($37&%/*%$"4$"Of"56*"%$0&6<%$",/" ,-)*&'I" f&6)" /<&')" 4-3&'(%-" 56$" ,@/0(*<*(-" 46" 7%&3&($6%" 46" 8`'$" a!b" $)(" /683$'(-$" 7/%" ,/" Of2"3/*)" 4*3*'6-$" 7/%" ,/" ,/3*'*'$" eEDg" 4/')" 4$)" 0$,,6,$)"-7*(1-,*/,$)"4$"0&%'-$"4$",/7*')"eA]AE)gI"=6*)56$",/")-0%-(*&'"46"0&,,/8`'$"$("4$",/"ED"</%*$"4$";/V&'"&77&)-$"."0$,,$"4$",/"Of",&%)"4$",/"0*0/(%*)/(*&'"0&%'-$''$2"'&6)"/<&')"-</,6-"4/')"0$(($"-(64$",$)"*';,6$'0$)"4$)"8$,)"4$"0&,,/8`'$"eAd2"AdJg"&6" 4$" ,/" 0&3+*'/*)&'"4$"7,6)*$6%)" 0&37&)/'($)" 4$" ,/"3/(%*0$" $>(%/0$,,6,/*%$"eD]Ag")6%",@/0(*<*(-"46"7%&3&($6%"a!bI"
DFSRYd]E" ]S" DRSMmC]#G" C$)" 7,/)3*4$)" 7&%(/'(" 4*;;-%$'()" )$83$'()" 46"7%&3&($6%" ! ab" ;6)*&''-)" /6" 8`'$" AFS" &'(" -(-" (%/');$0(-)" 4/')" 4$)" A]AE)" 06,(*<-$)")6%"8$,)"4$"Ad"&6"AdJ2"&6")6%"4$)"3/(%*0$)"0&37,$>$)"eDOANcbUg2"4-<*N(/,*)-$)"$("7%&46*($)"$'"06,(*</'("4$)";*+%&+,/)($)"4$"0&%'-$"$'"7%-)$'0$"4@/0*4$"/)0&%+*56$" 7$'4/'(" cb" U&6%)I" E/" 0&37&)*(*&'" 4$" 0$(($"3/(%*0$" $>(%/0$,,6,/*%$"0&37,$>$"/"-(-"/'/,?)-$"7/%"*336'&;,6&%$)0$'0$"*'4*%$0($"$(")7$0(%&3-(%*$"4$"3/))$I"C$)"/'/,?)$)"$'"+6</%4/8$"o$)($%'"$("4$)"/'/,?)$)"4$"%$(/%4")6%"8$,"e]D#Fg"&'("-(-"%-/,*)-)"7&6%"-</,6$%",@$>7%$))*&'"$(",@/0(*<*(-"4$",*/*)&'"4$)";/0N($6%)"4$"(%/')0%*7(*&')"eOS)g"#7\2"F=N\"$("fOd"56*"7/%(*0*7$'(".",/"(%/')0%*7(*&'"46"8`'$"a!bI"YR#HESFS#G"E/"3/(%*0$"0&37,$>$"$)("0&37&)-$"4$)"0&,,/8`'$)"d2"J2"Jd2"tdd"$("tdJ2"4$"Of2"4$"(-'/)0*'$2"4$"<*3$'(*'$"$("4$"7%&(-&8,?0/')I"E/"(%/');$0(*&'"4$)"7,/)3*4$)" abuAFS"/"7$%3*)"4$"4-3&'(%$%"56$" ,$)"0&,,/8`'$)"$>$%0$'("6'$";&%($"*';,6$'0$"'-8/(*<$")6%",@/0(*<*(-"46"7%&3&($6%"a!bI"E$)"/'/,?)$)"o$)($%'"$("]D#F)"&'("4-3&'(%-"6'$";&%($"%-460(*&'"4$",@$>7%$))*&'"$("4$",@/0(*<*(-"4$",*/*)&'".",@FCf"4$"F=N\"e6'"/0(*</($6%"76*))/'("46"8`'$"a!bg"4/')",$)"A]AE)"06,(*<-$)")6%" 8$,)" Ad" $("DOANcbU2" /,&%)" 56$" 0$)"3/(%*0$)" '@/;;$0($'(" 7/)" e&6" 7$6g" 0$)"7%&7%*-(-)"7&6%"#7\"e;/*+,$"/0(*</($6%g"$("fOd"e76*))/'("%-7%$))$6%"46"8`'$"a!bgI"
47Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
?5*(C"'[
Conclusion :"A&'(%/*%$3$'(".",/"Of2",$)"0&,,/8`'$)"$>$%0$'("6'$";&%($"*';,6$'0$"'-8/(*<$")6%",@/0(*<*(-"46"7%&3&($6%"! ab"$'"3&4*;*/'(",$"%/(*&"'60,-/*%$"4$)"OS)"F=N\u#7\NfOd"4$"3/'*`%$".";/<&%*)$%",@*';,6$'0$"'-8/(*<$"4$"fOdI"E$)"4*;;-%$'()"-,-3$'()" 4$" ,/"D]A" $>$%0$'(" /*')*" 4$)" /0(*&')" 4*)(*'0($)" )6%" ,@$>7%$))*&'" $(",@/0(*<*(-"46"7%&3&($6%"a!bI
Type de présentation : R(64*/'($"/6"4&0(&%/(Nom du directeur de la recherche : #?,</*'"Q6-%*'Nom du codirecteur :"Cr"A1%*)(*/'"#/,$))$"
48Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
?5*(C"'j
Interaction membranaire d’une neuroprotéine sensible au calcium (NCS), la recoverine : étude par spectroscopie de résonance magnétique nucléaire c7=Xd'")'$&5101%,G"'ckWBM7dS"&";$H;"'`03%$#BA0$330121,22"=1*,*77$"A/,<$h_2c2"A1%*)(*/'"#/,$))$_2c"$("D*01`,$"F68$%1
1"C-7/%($3$'("4$"01*3*$2"O/06,(-"4$")0*$'0$)"$("4$"8-'*$2"H'*<$%)*(-"E/</,I2"Em]t"u"AHmv%$01$%01$2"A$'(%$"4$"%$01$%01$"46"AMF2"Mi7*(/,"46"#(N#/0%$3$'(2"AMFI3"C-7/%($3$'("4@&71(/,3&,&8*$2"O/06,(-"4$"3-4$0*'$2"H'*<$%)*(-"E/</,I
Contexte et objectifs : E$)"fA#")&'("4$)"7%&(-*'$)"56*"7&))`4$'("l"4&3/*'$)"]ONM/'4"0&37&)-)"4$"_"1-,*0$)" a"%$,*-$)"7/%"6'$"+&60,$"4&'(",/")-56$'0$"$)("(%`)"0&')$%<-$I"E/"7,67/%("4$)"fA#"7&))`4$'("-8/,$3$'("6'$")-56$'0$"fN($%N3*'/,$"%$0&''6$"7/%",/"fND?%*)(&?,"(%/');-%/)$"56*"$)("%$)7&')/+,$"4$",@/0?,/N(*&'"4$"0$)"7%&(-*'$)I"z";/*+,$"0&'0$'(%/(*&'"$'"0/,0*632",$"8%&67$3$'("3?%*)(&?,"$)("$';&6*"." ,@*'(-%*$6%"4@6'$"7&01$"1?4%&71&+$"(/'4*)"56$" ,/" ,*/*)&'"4$"\"."l"*&')"0/,0*63"*'46*("4@*37&%(/'()"01/'8$3$'()"0&';&%3/(*&''$,)"/6")$*'"4$" ,/"7%&(-*'$"$("0&'46*)$'(".",@$>(%6)*&'"4$"0$"8%&67$3$'("e3-0/'*)3$"0&''6")&6)",$"'&3"4$"A/,0*63ND?%*)(&?,"#[*(01gI"A$(($"0/%/0(-%*)(*56$"7$%3$(".",/"7%&(-*'$"4$"7/))$%"4@6'$";&%3$"0?(&)&,*56$"."6'$";&%3$",*-$".",/"3$3+%/'$"56*"U&6$"6'"%i,$" *37&%(/'("4/')" ,/"0/)0/4$"4$"71&(&(%/')460(*&'"4$)"71&(&%-0$7($6%)I"]'"$;;$(2",@/+)&%7(*&'"4@6'"71&(&'"7/%",/"%1&4&7)*'$"$'(%/B'$"6'$"*37&%(/'($"016($"4$",/"0&'0$'(%/(*&'"*'(%/0$,,6,/*%$"$'"0/,0*63"56*"3`'$".",/"4*))&0*)(*&'"3$3N+%/'/*%$"4$",/"%$0&<$%*'$"$(",/",$<-$"4$",@*'1*+*(*&'"4$",/"%1&4&7)*'$"W*'/)$I"H'$"4?);&'0(*&'"4/')",@$>7%$))*&'"4$",/"%$0&<$%*'$"$)("4@/*,,$6%)"0&''6$"7&6%"0/6)$%"6'$";&%3$"4$"%-(*'&7/(1*$"/))&0*-$"/6"0/'0$%I"C@/6(%$"7/%(2"*,"$)("0&''6"56$",/"0&37&)*(*&'"3$3+%/'/*%$"4$)")$83$'()"$>($%'$)"4$)"71&(&%-0$7($6%)"$)("7/%N(*06,*`%$"/<$0"7,6)"4$"qr{"4$"71&)71&,*7*4$)"7&,?*')/(6%-)"e<$%)6)"!\r{"4/')",$)"/6(%$)"3$3+%/'$)"+*&,&8*56$)gI"E/"7%-)$'($"-(64$"<*)$"4&'0"."0&37%$'4%$"0&33$'(",/"7%-)$'0$"4$"0$)",*7*4$)"/;;$0($",/",*/*)&'"%-<$%)*+,$"4$",/"%$0&<$%*'$I"
Matériel et méthodes :"E/"YDf")&,*4$"46"c\="$("46"_M"&'("-(-"%$)7$0(*<$3$'("6(*,*)-$)"7&6%"&+($'*%"4$",@*';&%3/(*&'")6%",/"(9($"7&,/*%$"4$)",*7*4$)"/*')*"56$",$)"01/B'$)"/0?,$)"4$)",*7*4$)"$("4$",/"%$0&<$%*'$I"C$",@*';&%3/(*&'")6%",/"0&';&%3/N(*&'"4$",/"%$0&<$%*'$"$(" ,$)"(%/')*(*&')"4$"71/)$"4$)",*7*4$)"/"-(-"&+($'6$"7/%")7$0(%&)0&7*$"OSNdYI"
49Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
?5*(C"'j
76#,3)0)#' /163$.$&0$1"#' Y" E/" %$0&<$%*'$" /" -(-" )6%$>7%*3-$" 4/')" ]I0&,*" $(" 76%*;*-$"/<$0"6'"(%`)"1/6("%$'4$3$'(I"E/")7$0(%&)0&7*$"*';%/%&68$")688`%$"56$",/"7%-)$'0$"4$",*7*4$)"*'46*(",@/8%-8/(*&'"4$",/"%$0&<$%*'$")/6;"7&6%",/"%$0&<$%*'$"3?%*)(&?,-$"$'"7%-)$'0$"4$"0/,0*63I"E$)"4&''-$)"$'"YDf"46"c\=")688`%$'("56$",/"%$0&<$%*'$"3?%*)(&?,-$"/"6'"$;;$("7,6)"*37&%(/'("56$",/";&%3$"'&'N3?%*)(&?,-$")6%",$)",*7*4$)"$("56$"0$("$;;$("4-7$'4"46",*7*4$"-(64*-I"
Conclusion :"E/"0&37&)*(*&'"4$",/"3$3+%/'$",*7*4*56$"e'/(6%$"4$)"(9($)"7&,/*%$)2" ,&'86$6%"$("7%-)$'0$"4@*')/(6%/(*&'")6%",$)"01/B'$)"/0?,$)g"*';,6$'0$",/")(%60(6%$"$(",/",*/*)&'"4$",/"%$0&<$%*'$I
Type de présentation :"R(64*/'($".",/"3/B(%*)$Nom du directeur de la recherche :"Cre"D*01`,$"F68$%Nom du codirecteur :"Cr"A1%*)(*/'"#/,$))$
50Programme de la 27e journée annuelle de la recherche en opthalmologie 2011
Notes
Cette activité a été rendue possible grâce à une subvention sans restriction à l’éducation médicale continue.
Partenaires :
Pour information :cuo.recherche@fmed.ulaval.ca418 682-7663
Comité organisateur 2011 :Christian Salesse, PhD, PrésidentPhilippe Calvez, MScÉmmanuelle Chalifoux, R4 Béatrice Des Marchais, MD
Marcelle Giasson, BScPatricia-Ann Laughrea, MDAlain Rousseau, MD